publication_uri | type | publication_title | year | doi | pmid | journal_uri |
http://vivo.scripps.edu/individual/e2n227157 | AcademicArticle | Telomere length heterogeneity in ALT cells is maintained by PML-dependent localization of the BTR complex to telomeres | 2020 | 10.1101/gad.333963.119 | 32217664 | http://vivo.scripps.edu/individual/endnote235793 |
http://vivo.scripps.edu/individual/e2n144690 | AcademicArticle | New codons for efficient production of unnatural proteins in a semisynthetic organism | 2020 | 10.1038/s41589-020-0507-z | 32251411 | http://vivo.scripps.edu/individual/endnote16708 |
http://vivo.scripps.edu/individual/e2n373482 | AcademicArticle | Mapping RNAPII CTD phosphorylation reveals that the identity and modification of seventh heptad residues direct Tyr1 phosphorylation | 2019 | 10.1021/acschembio.9b00610 | 31553563 | http://vivo.scripps.edu/individual/endnote153903 |
http://vivo.scripps.edu/individual/e2n210636 | AcademicArticle | Tyr1 phosphorylation promotes phosphorylation of Ser2 on the C-terminal domain of eukaryotic RNA polymerase II by P-TEFb | 2019 | 10.7554/eLife.48725 | 31385803 | http://vivo.scripps.edu/individual/e2n358763 |
http://vivo.scripps.edu/individual/e2n14148 | AcademicArticle | Identification of the Formycin A biosynthetic gene cluster from streptomyces kaniharaensis illustrates the interplay between biological pyrazolopyrimidine formation and de novo purine biosynthesis | 2019 | 10.1021/jacs.9b00241 | 30942582 | http://vivo.scripps.edu/individual/endnote181842 |
http://vivo.scripps.edu/individual/e2n354391 | AcademicArticle | Structural, kinetic, and mechanistic analysis of an asymmetric 4-oxalocrotonate tautomerase trimer | 2019 | 10.1021/acs.biochem.9b00303 | 31074977 | http://vivo.scripps.edu/individual/endnote165634 |
http://vivo.scripps.edu/individual/e2n260536 | AcademicArticle | Structural determinants for accurate dephosphorylation of RNA polymerase II by its cognate C-terminal domain (CTD) phosphatase during eukaryotic transcription | 2019 | 10.1074/jbc.RA119.007697 | 30971428 | http://vivo.scripps.edu/individual/endnote308813 |
http://vivo.scripps.edu/individual/e2n323807 | AcademicArticle | Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST) | 2018 | 10.1074/jbc.RA118.004722 | 30217818 | http://vivo.scripps.edu/individual/endnote308813 |
http://vivo.scripps.edu/individual/e2n210438 | AcademicArticle | Chemical tools for studying the impact of cis/trans prolyl isomerization on signaling: a case study on RNA polymerase II phosphatase activity and specificity | 2018 | 10.1016/bs.mie.2018.04.020 | 30149861 | http://vivo.scripps.edu/individual/endnote139079 |
http://vivo.scripps.edu/individual/e2n158332 | AcademicArticle | Structural characterization of the hydratase-aldolases, NahE and PhdJ: implications for the specificity, catalysis, and N-acetylneuraminate lyase subgroup of the aldolase superfamily | 2018 | 10.1021/acs.biochem.8b00532 | 29856600 | http://vivo.scripps.edu/individual/endnote165634 |
http://vivo.scripps.edu/individual/e2n293951 | AcademicArticle | Inactivation of 4-oxalocrotonate tautomerase by 5-Halo-2-hydroxy-2,4-pentadienoates | 2018 | 10.1021/acs.biochem.7600899 | 29303557 | http://vivo.scripps.edu/individual/endnote165634 |
http://vivo.scripps.edu/individual/e2n274877 | AcademicArticle | A global view of structure-function relationships in the tautomerase superfamily | 2018 | 10.1074/jbc.M117.815340 | 29184004 | http://vivo.scripps.edu/individual/endnote308813 |
http://vivo.scripps.edu/individual/e2n128436 | AcademicArticle | Snapshots of C-S cleavage in Egt2 reveals substrate specificity and reaction mechanism | 2018 | 10.1016/j.chembiol.2018.02.002 | 29503207 | http://vivo.scripps.edu/individual/e2n73778 |
http://vivo.scripps.edu/individual/e2n10604 | AcademicArticle | Phosphorylation induces sequence-specific conformational switches in the RNA polymerase II C-terminal domain | 2017 | 10.1038/ncomms15233 | 28497798 | http://vivo.scripps.edu/individual/endnote367622 |
http://vivo.scripps.edu/individual/e2n85559 | AcademicArticle | Kinetic and structural characterization of a cis-3-Chloroacrylic acid dehalogenase homologue in Pseudomonas sp UW4: A potential step between subgroups in the tautomerase superfamily | 2017 | 10.1016/j.abb.2017.10.018 | 29111295 | http://vivo.scripps.edu/individual/endnote220293 |
http://vivo.scripps.edu/individual/e2n347502 | AcademicArticle | Mapping the phosphorylation pattern of Drosophila melanogaster RNA polymerase II carboxyl-terminal domain using ultraviolet photodissociation mass spectrometry | 2017 | 10.1021/acschembio.6b00729 | 28103682 | http://vivo.scripps.edu/individual/endnote153903 |
http://vivo.scripps.edu/individual/e2n258943 | AcademicArticle | Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth | 2017 | 10.1038/nm.4232 https://www.nature.com/articles/nm.4232#supplementary-information | 27869804 | http://vivo.scripps.edu/individual/endnote267122 |
http://vivo.scripps.edu/individual/e2n358871 | AcademicArticle | IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions | 2017 | 10.1038/ni.3770 | 28604720 | http://vivo.scripps.edu/individual/endnote396893 |
http://vivo.scripps.edu/individual/e2n396351 | AcademicArticle | Structural snapshots of an engineered cystathionine-γ-lyase reveal the critical role of electrostatic interactions in the active site | 2017 | 10.1021/acs.biochem.6b01172 | 28106980 | http://vivo.scripps.edu/individual/endnote165634 |
http://vivo.scripps.edu/individual/e2n313237 | AcademicArticle | Structural heterogeneity in the intrinsically disordered RNA polymerase II C-terminal domain | 2017 | 10.1038/ncomms15231 | 28497792 | http://vivo.scripps.edu/individual/endnote367622 |
http://vivo.scripps.edu/individual/e2n39208 | AcademicArticle | The bacterial catabolism of polycyclic aromatic hydrocarbons: Characterization of three hydratase-aldolase-catalyzed reactions | 2016 | https://doi.org/10.1016/j.pisc.2016.03.025 | http://vivo.scripps.edu/individual/e2n239461 | |
http://vivo.scripps.edu/individual/e2n185506 | AcademicArticle | Intramolecular cleavage of the hASRGL1 homodimer occurs in two stages | 2016 | 10.1021/acs.biochem.5b01157 | 26780688 | http://vivo.scripps.edu/individual/endnote165634 |
http://vivo.scripps.edu/individual/e2n356688 | AcademicArticle | Structure of Saccharomyces cerevisiae Rtr1 reveals an active site for an atypical phosphatase | 2016 | 10.1126/scisignal.aad4805 | 26933063 | http://vivo.scripps.edu/individual/endnote337317 |
http://vivo.scripps.edu/individual/e2n36042 | AcademicArticle | Dephosphorylating eukaryotic RNA polymerase II | 2016 | 10.1016/j.bbapap.2016.01.007 | 26779935 | http://vivo.scripps.edu/individual/e2n142586 |
http://vivo.scripps.edu/individual/e2n80502 | AcademicArticle | Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease | 2015 | 10.1016/j.nbd.2014.12.027 | 25576397 | http://vivo.scripps.edu/individual/endnote115958 |
http://vivo.scripps.edu/individual/e2n38618 | AcademicArticle | Chemical tools to decipher regulation of phosphatases by proline isomerization on eukaryotic RNA polymerase II | 2015 | 10.1021/acschembio.5b00296 | 26332362 | http://vivo.scripps.edu/individual/endnote153903 |
http://vivo.scripps.edu/individual/e2n66801 | AcademicArticle | Depletion of fat-resident T-reg cells prevents age-associated insulin resistance | 2015 | 10.1038/nature16151 | 26580014 | http://vivo.scripps.edu/individual/endnote351395 |
http://vivo.scripps.edu/individual/e2n200681 | AcademicArticle | Endoperoxide formation by an α-ketoglutarate-dependent mononuclear non-haem iron enzyme | 2015 | 10.1038/nature15519 | 26524521 | http://vivo.scripps.edu/individual/endnote351395 |
http://vivo.scripps.edu/individual/e2n79063 | AcademicArticle | A potent and selective inhibitor for the UBLCP1 proteasome phosphatase | 2015 | 10.1016/j.bmc.2015.03.066 | 25907364 | http://vivo.scripps.edu/individual/endnote193708 |
http://vivo.scripps.edu/individual/e2n216856 | AcademicArticle | Cross-talk of phosphorylation and prolyl isomerization of the C-terminal domain of RNA Polymerase II | 2014 | 10.3390/molecules19021481 | 24473209 | http://vivo.scripps.edu/individual/endnote281820 |
http://vivo.scripps.edu/individual/e2n35321 | AcademicArticle | Characterization of native protein complexes using ultraviolet photodissociation mass spectrometry | 2014 | 10.1021/ja505217w | 25148649 | http://vivo.scripps.edu/individual/endnote181842 |
http://vivo.scripps.edu/individual/e2n242828 | AcademicArticle | Viewing serine/threonine protein phosphatases through the eyes of drug designers | 2013 | 10.1111/febs.12481 | 23937612 | http://vivo.scripps.edu/individual/endnote203539 |
http://vivo.scripps.edu/individual/e2n219301 | AcademicArticle | Complete protein characterization using top-down mass spectrometry and ultraviolet photodissociation | 2013 | 10.1021/ja4029654 | 23697802 | http://vivo.scripps.edu/individual/endnote181842 |
http://vivo.scripps.edu/individual/e2n172401 | AcademicArticle | Novel modifications on C-terminal domain of RNA polymerase II can fine-tune the phosphatase activity of Ssu72 | 2013 | 10.1021/cb400229c | 23844594 | http://vivo.scripps.edu/individual/endnote153903 |
http://vivo.scripps.edu/individual/e2n109956 | AcademicArticle | Calcium/calmodulin stimulates the autophosphorylation of elongation factor 2 kinase on Thr-348 and Ser-500 to regulate its activity and calcium dependence | 2012 | 10.1021/bi201788e | 22329831 | http://vivo.scripps.edu/individual/endnote165634 |
http://vivo.scripps.edu/individual/e2n133549 | AcademicArticle | Uncoupling intramolecular processing and substrate hydrolysis in the N-terminal nucleophile hydrolase hASRGL1 by circular permutation | 2012 | 10.1021/cb300232n | 22891768 | http://vivo.scripps.edu/individual/endnote153903 |
http://vivo.scripps.edu/individual/e2n244416 | AcademicArticle | Structural and kinetic analysis of prolyl-isomerization/phosphorylation cross-talk in the CTD code | 2012 | 10.1021/cb3000887 | 22670809 | http://vivo.scripps.edu/individual/endnote153903 |
http://vivo.scripps.edu/individual/e2n211482 | AcademicArticle | Selective inactivation of a human neuronal silencing phosphatase by a small molecule inhibitor | 2011 | 10.1021/cb100357t | 21348431 | http://vivo.scripps.edu/individual/endnote153903 |
http://vivo.scripps.edu/individual/e2n98255 | AcademicArticle | Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogue | 2011 | 10.1042/bj20101471 | 21204787 | http://vivo.scripps.edu/individual/endnote277207 |
http://vivo.scripps.edu/individual/e2n204607 | AcademicArticle | Kinetic, crystallographic, and mechanistic characterization of TomN: elucidation of a function for a 4-oxalocrotonate tautomerase homologue in the tomaymycin biosynthetic pathway | 2011 | 10.1021/bi200947w | 21809870 | http://vivo.scripps.edu/individual/endnote165634 |
http://vivo.scripps.edu/individual/e2n61691 | AcademicArticle | A reduced-amide inhibitor of Pin1 binds in a conformation resembling a twisted-amide transition state | 2011 | 10.1021/bi201055c | 21980916 | http://vivo.scripps.edu/individual/endnote165634 |
http://vivo.scripps.edu/individual/e2n261922 | AcademicArticle | Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function | 2011 | 10.1016/j.molcel.2011.03.005 | 21497122 | http://vivo.scripps.edu/individual/endnote331988 |
http://vivo.scripps.edu/individual/e2n289935 | AcademicArticle | Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase, Scp1 | 2010 | 10.1002/pro.375 | 20222012 | http://vivo.scripps.edu/individual/endnote61860 |
http://vivo.scripps.edu/individual/e2n41877 | AcademicArticle | Bio-molecular architects: a scaffold provided by the C-terminal domain of eukaryotic RNA polymerase II | 2010 | 10.3402/nano.v1i0.5502 | 22110856 | http://vivo.scripps.edu/individual/e2n152902 |
http://vivo.scripps.edu/individual/e2n43615 | AcademicArticle | Structural basis for high-affinity peptide inhibition of human Pin1 | 2007 | 10.1021/cb7000044 | 17518432 | http://vivo.scripps.edu/individual/endnote153903 |
http://vivo.scripps.edu/individual/endnote6614 | AcademicArticle | Structure-function-folding relationship in a WW domain | 2006 | 10.1073/pnas.0600511103 | 16807295 | http://vivo.scripps.edu/individual/endnote71945 |
http://vivo.scripps.edu/individual/endnote240992 | AcademicArticle | Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1 | 2006 | 10.1016/j.molcel.2006.10.027 | 17157258 | http://vivo.scripps.edu/individual/endnote331988 |
http://vivo.scripps.edu/individual/endnote291060 | AcademicArticle | Synthesis and biological evaluation of N-{4- 5-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-2-(2,2,2-trifluoro acetyl)pentyl)benzoyl}-L-glutamic acid as a potential inhibitor of GAR Tfase and the de novo purine biosynthetic pathway | 2005 | 10.1016/j.bme.2004.11.049 | 15848772 | http://vivo.scripps.edu/individual/endnote193708 |
http://vivo.scripps.edu/individual/endnote289349 | AcademicArticle | Synthesis and biological evaluation of α- and γ-carboxamide derivatives of 10-CF3CO-DDACTHF | 2005 | 10.1016/j.bme.2004.11.050 | 15848771 | http://vivo.scripps.edu/individual/endnote193708 |
http://vivo.scripps.edu/individual/endnote287545 | AcademicArticle | Design, synthesis, and biological evaluation of 10-methanesulfonyl-DDACTHF, 10-methanesulfonyl-5-DACTHF, and 10-methylthio-DDACTHF as potent inhibitors of GAR Tfase and the de novo purine biosynthetic pathway | 2005 | 10.1016/j.bmc.2004.12.004 | 15848770 | http://vivo.scripps.edu/individual/endnote193708 |
http://vivo.scripps.edu/individual/endnote213391 | AcademicArticle | Crystal structures of apo wild-type M. jannaschii tyrosyl-tRNA synthetase (TyrRS) and an engineered TyrRS specific for O-methyl-L-tyrosine | 2005 | 10.1110/ps.041239305 | 15840835 | http://vivo.scripps.edu/individual/endnote61860 |
http://vivo.scripps.edu/individual/e2n159186 | AcademicArticle | Bifunctional abletadiene synthase: mutual structural dependence of the active sites for protonation-initiated and ionization-initiated cyclizations | 2003 | 10.1021/bi020492n | 12614165 | http://vivo.scripps.edu/individual/endnote165634 |
http://vivo.scripps.edu/individual/endnote147585 | AcademicArticle | Design, synthesis and biological evaluation of 10-CF3CO-DDACTHF analogues and derivatives as inhibitors of GAR Tfase and the de novo purine biosynthetic pathway | 2003 | 10.1016/s0968-0896(03)00458-9 | 13129587 | http://vivo.scripps.edu/individual/endnote193708 |
http://vivo.scripps.edu/individual/endnote359072 | AcademicArticle | Rational design, synthesis, evaluation, and crystal structure of a potent inhibitor of human GAR Tfase: 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid | 2003 | 10.1021/bi034219c | 12755606 | http://vivo.scripps.edu/individual/endnote165634 |
http://vivo.scripps.edu/individual/endnote172922 | AcademicArticle | Design, synthesis, and biological evaluation of simplified alpha-keto heterocycle, trifluoromethyl ketone, and formyl substituted folate analogues as potential inhibitors of GAR transformylase and AICAR transformylase | 2003 | 10.1016/s0968-0896(03)00456-5 | 13129585 | http://vivo.scripps.edu/individual/endnote193708 |
http://vivo.scripps.edu/individual/endnote62339 | AcademicArticle | 10-(2-benzoxazolcarbonyl)-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid: a potential inhibitor of GAR transformylase and AICAR transformylase | 2003 | 10.1016/s0968-0896(03)00457-7 | 13129586 | http://vivo.scripps.edu/individual/endnote193708 |
http://vivo.scripps.edu/individual/endnote384272 | AcademicArticle | Crystal structures of human GAR Tfase at low and high pH and with substrate β-GAR | 2002 | 10.1021/bi020522m | 12450384 | http://vivo.scripps.edu/individual/endnote165634 |
http://vivo.scripps.edu/individual/endnote34329 | AcademicArticle | 10-formyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid (10-formyl-DDACTHF): a potent cytotoxic agent acting by selective inhibition of human GAR Tfase and the de novo purine biosynthetic pathway | 2002 | 10.1016/s0968-0896(02)00102-5 | 12057663 | http://vivo.scripps.edu/individual/endnote193708 |
http://vivo.scripps.edu/individual/e2n222313 | AcademicArticle | Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues | 1999 | 10.1021/bi991711g | 10555963 | http://vivo.scripps.edu/individual/endnote165634 |