Academic Article
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5-HT(2C) agonists as therapeutics for the treatment of schizophrenia
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5-HT(6) receptor antagonism potentiates the behavioral and neurochemical effects of amphetamine but not cocaine
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5-HT(7) receptor inhibition and inactivation induce antidepressantlike behavior and sleep pattern
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5-HT1A autoreceptors in the dorsal raphe nucleus convey vulnerability to compulsive cocaine seeking
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5-HT2C receptor structures reveal the structural basis of GPCR polypharmacology
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5-Lipoxygenase-activating protein inhibitors. Part 2: 3-{5-((S)-1-Acetyl-2,3-dihydro-1H-indol-2-ylmethoxy)-3-tert-butylsulfany l-1- 4-(5-methoxy-pyrimidin-2-yl)-benzyl -1H-indol-2-yl}-2,2-dimethyl-pr opionic acid (AM679)-A potent FLAP inhibitor
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5-lipoxygenase-activating protein inhibitors: development of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103)
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5-N,4-O-carbonyl-7,8,9-tri-O-chloroacetyl-protected sialyl donor for the stereoselective synthesis of alpha-(2-->9)-tetrasialic acid
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5S rRNA gene transcription factor IIIA alters the helical configuration of DNA
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6,7-dihydroxyisoquinoline-3-carboxylic acids are potent inhibitors on the binding of insulin-like growth factor (IGF) to IGF-binding proteins: Optimization of the 1-position benzoyl side chain
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6,8-di-C-glycosyl flavonoids from Dendrobium huoshanense
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6,9-pyridazaprostacyclin and derivatives: the first "aromatic" prostacyclins
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6,9-thiaprostacyclin. A stable and biologically potent analogue of prostacyclin (PGI2)
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6-alkynyl fucose is a bioorthogonal analog for O-fucosylation of epidermal growth factor-like repeats and thrombospondin Type-1 repeats by protein O-fucosyltransferases 1 and 2
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6-Deoxyerythronolide B synthase thioesterase-catalyzed macrocyclization is highly stereoselective
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6-endo-hydroxy-3-endo-aminomethylbicyclo[2.2.1]heptane-2-endo-carboxylic acid lactam
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68Ga-PSMA-11 PET imaging of response to androgen receptor inhibition: first human experience
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7-alkylidenecephalosporin esters as inhibitors of human leukocyte elastase
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7-Chlorokynurenate Ameliorates Neuronal Injury Mediated by HIV Envelope Protein gp120 in Rodent Retinal Cultures
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7-Hydroxynaphthalen-1-yl-urea and -amide antagonists of human vanilloid receptor 1
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7-iron ferredoxin revisited
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7-nitroindazole, nitric oxide synthase inhibitor, attenuates physical dependence on butorphanol in rat
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8-Azaguanine reporter of purine ionization states in structured RNAs
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8-Br-cyclic GMP mimics activation of muscarinic autoreceptor and inhibits acetylcholine release from rat hippocampal slices
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8-epi-Salvinorin B: crystal structure and affinity at the kappa opioid receptor
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8-Hydroxyquinoline and hydroxamic acid inhibitors of botulinum neurotoxin BoNT/A
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8-OH-DPAT acts on both 5-HT1A and 5-HT7 receptors to induce hypothermia in rodents
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8-Tetrahydropyran-2-yl chromans: highly selective beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors
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8-triazolylpurines: towards fluorescent inhibitors of the MDM2/p53 interaction
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9-membered carbocycle formation: development of distinct Friedel-Crafts cyclizations and application to a scalable total synthesis of ( +/-)- caraphenol A
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