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Proteasome Inhibitors

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  • A novel Rac1 GAP splice variant relays poly-Ub accumulation signals to mediate Rac1 inactivation  Academic Article
  • A reversible and highly selective inhibitor of the proteasomal ubiquitin receptor rpn13 is toxic to multiple myeloma cells  Academic Article
  • Activation of the ubiquitin proteasome pathway in a mouse model of inflammatory myopathy: a potential therapeutic target  Academic Article
  • An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer  Academic Article
  • Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance  Academic Article
  • Antimitotic agents of natural origin  Academic Article
  • Fbw7alpha and fbw7gamma collaborate to shuttle cyclin e1 into the nucleolus for multiubiquitylation  Academic Article
  • Global analysis of posttranslational protein arginylation  Academic Article
  • HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells  Academic Article
  • Hemerythrin-like domain within F-box and leucine-rich repeat protein 5 (FBXL5) communicates cellular iron and oxygen availability by distinct mechanisms  Academic Article
  • Identification of a peptoid inhibitor of the proteasome 19S regulatory particle  Academic Article
  • Palau'amine and related oroidin alkaloids dibromophakellin and dibromophakellstatin inhibit the human 20s proteasome  Academic Article
  • Periodate-triggered cross-linking reveals Sug2/Rpt4 as the molecular target of a peptoid inhibitor of the 19S proteasome regulatory particle  Academic Article
  • Proteasome activity imaging and profiling characterizes bacterial effector syringolin A  Academic Article
  • Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness  Academic Article
  • Proteasome inhibitor drugs on the rise  Academic Article
  • Protein degradation by the proteasome is required for synaptic tagging and the heterosynaptic stabilization of hippocampal late-phase long-term potentiation  Academic Article
  • Proteolytic turnover of the Gal4 transcription factor is not required for function in vivo  Academic Article
  • Pseudomonas syringae pv. syringae uses proteasome inhibitor syringolin A to colonize from wound infection sites  Academic Article
  • Rapid identification of the pharmacophore in a peptoid inhibitor of the proteasome regulatory particle  Academic Article
  • S-Nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration  Academic Article

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