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Enzyme Assays

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  • 2-Bromopalmitate analogues as activity-based probes to explore palmitoyl acyltransferases  Academic Article
  • A cleavage enzyme-cytometric bead array provides biochemical profiling of resistance mutations in HIV-1 Gag and protease  Academic Article
  • A plate-based high-throughput activity assay for polysialyltransferase from Neisseria meningitidis  Academic Article
  • A simple solid phase, peptide-based fluorescent assay for the efficient and universal screening of hrv 3c protease inhibitors  Academic Article
  • Acoustic deposition with nims as a high-throughput enzyme activity assay  Academic Article
  • An acyloxymethyl ketone-based probe to monitor the activity of glutathionylspermidine amidase in Escherichia coli  Academic Article
  • Application of activity-based protein profiling to study enzyme function in adipocytes  Academic Article
  • Chemical tools for studying the impact of cis/trans prolyl isomerization on signaling: a case study on RNA polymerase II phosphatase activity and specificity  Academic Article
  • Development of Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) inhibitors with potent anti-toxoplasma activity  Academic Article
  • Discovery of potent and selective urea-based ROCK inhibitors: Exploring the inhibitor's potency and ROCK2/PKA selectivity by 3D-QSAR, molecular docking and molecular dynamics simulations  Academic Article
  • Enzyme-catalyzed transfer of a ketone group from an S-adenosylmethionine analogue: a tool for the functional analysis of methyltransferases  Academic Article
  • Functional interrogation of kinases and other nucleotide-binding proteins  Academic Article
  • Glutathione transferases immobilized on nanoporous alumina: Flow system kinetics, screening, and stability  Academic Article
  • High-throughput FRET assay yields allosteric SERCA activators  Academic Article
  • In silico and intuitive predictions of cyp46a1 inhibition by marketed drugs with subsequent enzyme crystallization in complex with fluvoxamine  Academic Article
  • Optimization of a non-radioactive high-throughput assay for decarboxylase enzymes  Academic Article
  • Self-assembly of PNA-encoded peptides into microarrays  Academic Article
  • Structural basis of substrate methylation and inhibition of SMYD2  Academic Article
  • Structures of the human LONP1 protease reveal regulatory steps involved in protease activation  Academic Article
  • Synthesis and evaluation of substrate analogue inhibitors of trypanothione reductase  Academic Article
  • Use of high-throughput mass spectrometry to reduce false positives in protease uHTS screens  Academic Article

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