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Nicotinamide Phosphoribosyltransferase

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  • Discovery of potent and efficacious cyanoguanidine-containing nicotinamide phosphoribosyltransferase (Nampt) inhibitors  Academic Article
  • Fragment-based design of 3-aminopyridine-derived amides as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)  Academic Article
  • Fragment-based identification of amides derived from trans-2-(pyridin-3-yl)cyclopropanecarboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)  Academic Article
  • Identification of 2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-derived ureas as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)  Academic Article
  • Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)  Academic Article
  • Identification of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with no evidence of CYP3A4 time-dependent inhibition and improved aqueous solubility  Academic Article
  • Involvement of the clock gene Rev-erb alpha in the regulation of glucagon secretion in pancreatic alpha-cells  Academic Article
  • Minimizing CYP2C9 inhibition of exposed-pyridine NAMPT (nicotinamide phosphoribosyltransferase) inhibitors  Academic Article
  • Mitochondrial complex i activity and nad(+)/nadh balance regulate breast cancer progression  Academic Article
  • Nicotinamide phosphoribosyltransferase can affect metastatic activity and cell adhesive functions by regulating integrins in breast cancer  Academic Article
  • Retinal Toxicity, in vivo and in vitro, Associated with Inhibition of Nicotinamide Phosphoribosyltransferase  Academic Article
  • Structural and biochemical analyses of the catalysis and potency impact of inhibitor phosphoribosylation by human nicotinamide phosphoribosyltransferase  Academic Article
  • Structure-based discovery of novel amide-containing nicotinamide phosphoribosyltransferase (nampt) inhibitors.  Academic Article
  • Structure-based identification of ureas as novel nicotinamide phosphoribosyltransferase (Nampt) inhibitors  Academic Article

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