subject area of
- 3,4,5-trisubstituted isoxazoles as novel PPAR delta agonists. Part 1 Academic Article
- A cdk-independent function of mammalian cks1: Targeting of scfskp2 to the cdk inhibitor p27(kip1) Academic Article
- A cell-free biochemical complementation assay reveals complex and redundant cytosolic requirements for lrp endocytosis Academic Article
- A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis Academic Article
- A conserved motif in the itk ph-domain is required for phosphoinositide binding and tcr signaling but dispensable for adaptor protein interactions Academic Article
- A five-amino-acid motif in the undefined region of the tlr8 ectodomain is required for species-specific ligand recognition Academic Article
- A free terminal carboxylate group is required for phra pentapeptide inhibition of rapa phosphatase Academic Article
- A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2g12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120 Academic Article
- A highly conserved arginine in gp120 governs HIV-1 binding to both syndecans and CCR5 via sulfated motifs Academic Article
- A method for defining binding sites involved in protein-protein interactions: analysis of the binding of plasminogen activator inhibitor 1 to the somatomedin domain of vitronectin Academic Article
- A new family of aspartyl phosphate phosphatases targeting the sporulation transcription factor spo0a of bacillus subtilis Academic Article
- A new functional domain of guanine nucleotide dissociation inhibitor (alpha-gdi) involved in rab recycling Academic Article
- A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase Academic Article
- A novel loop-loop recognition motif in the yeast ribosomal protein L30 autoregulatory RNA complex Academic Article
- A peptide core motif for binding to heterotrimeric G protein α subunits Academic Article
- A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin Academic Article
- A role for peroxisomes in photomorphogenesis and development of Arabidopsis Academic Article
- A structural framework for deciphering the link between I-A(g7) and autoimmune diabetes Academic Article
- ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1 Academic Article
- Aak1-mediated mu 2 phosphorylation is stimulated by assembled clathrin Academic Article
- Adenovirus serotype 5 fiber shaft influences in vivo gene transfer in mice Academic Article
- Alanyl-tRNA synthetase crystal structure and design for acceptor-stem recognition Academic Article
- Alternative chemistries for the synthesis of thrombospondin-1 type 1 repeats Academic Article
- Alternative splicing of a beta4 subunit proline-rich motif regulates voltage-dependent gating and toxin block of Ca(v)2.1 Ca2+ channels Academic Article
- An EB1-binding motif acts as a microtubule tip localization signal Academic Article
- An evolutionary perspective on eukaryotic membrane trafficking Academic Article
- Anti-Gag cytolytic T lymphocytes specific for an alternative translational reading frame-derived epitope and resistance versus susceptibility to retrovirus-induced murine AIDS in F(1) mice Academic Article
- Antigen recognition by variable lymphocyte receptors Academic Article
- Apparent loss-of-function mutant GPCRs revealed as constitutively desensitized receptors Academic Article
- Aromatic amino acids providing characteristic motifs in the Raman and SERS spectroscopy of peptides Academic Article
- Association of p130(cas) with phosphatidylinositol-3-oh kinase mediates adenovirus cell entry Academic Article
- Biarsenical-tetracysteine motif as a fluorescent tag for detection in capillary electrophoresis Academic Article
- Biochemistry. Ubiquitination - more than two to tango Academic Article
- Blmiii and bimiv nonribosornal peptide synthetase-catalyzed biosynthesis of the bleomycin bithiazole moiety involving both in cis and in trans aminoacylation Academic Article
- Broadly neutralizing anti-hiv antibody 4e10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41 Academic Article
- Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41 Academic Article
- CPSF30 and Wdr33 directly bind to AAUAAA in mammalian mRNA 3 ' processing Academic Article
- Casein kinase-2 mediates cell survival through phosphorylation and degradation of inositol hexakisphosphate kinase-2 Academic Article
- Cataracts and microphthalmia caused by a Gja8 mutation in extracellular loop 2 Academic Article
- Changes in active site histidine hydrogen bonding trigger cryptochrome activation Academic Article
- Characterization of the iron-sulfur cluster n7 (n1c) in the subunit nuog of the proton-translocating nadh-quinone oxidoreductase from escherichia coli Academic Article
- Cip1 and Cip2 are novel RNA-recognition-motif proteins that counteract Csx1 function during oxidative stress Academic Article
- Circadian clock activity of cryptochrome relies on tryptophan-mediated photoreduction Academic Article
- Cloning of the Arabidopsis clock cone TOC1, an autoregulatory response regulator homolog Academic Article
- Co-folding of a FliF-FliG split domain forms the basis of the MS:C ring interface within the bacterial flagellar motor Academic Article
- Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold Academic Article
- Computational design of high-affinity epitope scaffolds by backbone grafting of a linear epitope Academic Article
- Conformational flexibility in crystal structures of human 11 β-hydroxysteroid dehydrogenase type I provide insights into glucocorticoid interconversion and enzyme regulation Academic Article
- Conserved cysteines in the sialyltransferase sialylmotifs form an essential disulfide bond Academic Article
- Conserved xpb core structure and motifs for DNA unwinding: Implications for pathway selection of transcription or excision repair Academic Article
- Constitutive nadph oxidase 4 activity resides in the composition of the b-loop and the penultimate c terminus Academic Article
- Contribution of glycine 146 to a conserved folding module affecting stability and refolding of human glutathione transferase P1-1 Academic Article
- Crystal structure and novel recognition motif of rho adp-ribosylating c3 exoenzyme from clostridium botulinum: Structural insights for recognition specificity and catalysis Academic Article
- Crystal structure of NMA 1982 from Neisseria meningiddis at 1.5 Å resolution provides a structural scaffold for nonclassical, eukaryotic-like phosphatases Academic Article
- Crystal structure of a human aminoacyl-tRNA synthetase cytokine Academic Article
- Crystal structure of botulinum neurotoxin type g light chain: Serotype divergence in substrate recognition Academic Article
- Crystal structure of full-length Zika virus NS5 protein reveals a conformation similar to Japanese encephalitis virus NS5 Academic Article
- Crystal structure of human toll-like receptor 3 (tlr3) ectodomain Academic Article
- Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain Academic Article
- Crystal structure of the Fic (Filamentation induced by cAMP) family protein SO4266 (gi|24375750) from Shewanella oneidensis MR-1 at 1.6 A resolution Academic Article
- Crystal structures of two novel dye-decolorizing peroxidases reveal a β-barrel fold with a conserved heme-binding motif Academic Article
- CtIP protein dimerization is critical for its recruitment to chromosomal DNA double-stranded breaks Academic Article
- Cystinosin, the protein defective in cystinosis, is a h+-driven lysosomal cystine transporter Academic Article
- DNA binding and nucleotide flipping by the human DNA repair protein agt Academic Article
- DNA binding domain in the replication checkpoint protein Mrc1 of Schizosaccharomyces pombe Academic Article
- Deciphering the role of histidine 252 in mycobacterial adenosine 5'-phosphosulfate (APS) reductase catalysis Academic Article
- Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors Academic Article
- Design, synthesis, and biological evaluation of hiv/fiv protease inhibitors incorporating a conformationally constrained macrocycle with a small p3 ' residue Academic Article
- Detailed characterization of the peptide binding specificity of five common Patr class I MHC molecules Academic Article
- Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis Academic Article
- Determinants of the heme-CO vibrational modes in the H-NOX family Academic Article
- Di-acidic motifs in the membrane-distal C termini modulate the transport of angiotensin II receptors from the endoplasmic reticulum to the cell surface Academic Article
- Dissociating quaternary structure regulates cell-signaling functions of a secreted human tRNA synthetase Academic Article
- Distinct domains of tRNA synthetase recognize the same base pair Academic Article
- Distinct mechanisms control the stability of the related s-phase cyclins clb5 and clb6 Academic Article
- Distinct protein classes including novel merozoite surface antigens in Raft-like membranes of Plasmodium falciparum Academic Article
- Disulfide-bond formation by a single cysteine mutation in adenovirus protein vi impairs capsid release and membrane lysis Academic Article
- Drosophila TRF2 is a preferential core promoter regulator Academic Article
- Dual recruitment of Cdc48 (p97)-Ufd1-Npl4 ubiquitin-selective segregase by small ubiquitin-like modifier protein (SUMO) and ubiquitin in SUMO-targeted ubiquitin ligase-mediated genome stability functions Academic Article
- Dual roles for an arginine-rich motif in specific genome recognition and localization of viral coat protein to rna replication sites in flock house virus-infected cells Academic Article
- E3 ubiquitin-protein ligase activity of Parkin is dependent on cooperative interaction of RING finger (TRIAD) elements Academic Article
- Engineered mutations change the structure and stability of a virus-like particle Academic Article
- Envelope diversity, characteristics of V3 region and predicted co-receptor usage of human immunodeficiency viruses infecting north Indians Academic Article
- Eukaryotic class II cyclobutane pyrimidine dimer photolyase structure reveals basis for improved ultraviolet tolerance in plants Academic Article
- Evidence that YycJ is a novel 5 '-3 ' double-stranded DNA exonuclease acting in Bacillus anthracis mismatch repair Academic Article
- Evolution of the hemagglutinin protein of the new pandemic H1N1 influenza virus: maintaining optimal receptor binding by compensatory substitutions Academic Article
- Evolutionary and taxonomic implications of conserved structural motifs between picornaviruses and insect picorna-like viruses Academic Article
- Exploring the repeat protein universe through computational protein design Academic Article
- Fast dynamics of HP35 for folded and urea-unfolded conditions Academic Article
- Fine mapping of murine antibody responses to immunization with a novel soluble form of hepatitis C virus envelope glycoprotein complex Academic Article
- From benchmarking HITS-CLIP peak detection programs to a new method for identification of miRNA-binding sites from Ago2-CLIP data Academic Article
- Functional advantages of dynamic protein disorder Academic Article
- GC-GAP, a Rho family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2 Academic Article
- GIPC is recruited by APPL to peripheral TrkA endosomes and regulates TrkA trafficking and signaling Academic Article
- GSK3beta phosphorylation modulates CLASP-microtubule association and lamella microtubule attachment Academic Article
- Gain-of-function mutational activation of human tRNA synthetase procytokine Academic Article
- Genetic and biochemical evidence for an oligomeric structure of the functional L polymerase of the prototypic arenavirus lymphocytic choriomeningitis virus Academic Article
- Genetically encoded fragment-based discovery of glycopeptide ligands for carbohydrate-binding proteins Academic Article
- Genomic-scale comparison of sequence- and structure-based methods of function prediction: Does structure provide additional insight? Academic Article
- Genomics, evolution, and crystal structure of a new family of bacterial spore kinases Academic Article
- Glycation of the amyloid beta-protein by a nicotine metabolite: A fortuitous chemical dynamic between smoking and Alzheimer's disease Academic Article
- HSP90 regulates cell survival via inositol hexakisphosphate kinase-2 Academic Article
- Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger Academic Article
- Helical domain and kinase domain mutations in p110 alpha of phosphatidylinositol 3-kinase induce gain of function by different mechanisms Academic Article
- Heparin antagonism by polyvalent display of cationic motifs on virus-like particles Academic Article
- Highly selective cyclic peptide ligands for NeutrAvidin and avidin identified by phage display Academic Article
- Homo-oligomerization is the essential function of the tandem BRCT domains in the checkpoint protein Crb2 Academic Article
- Human abh3 structure and key residues for oxidative demethylation to reverse DNA/rna damage Academic Article
- Human/chicken urokinase chimeras demonstrate sequences outside the serine protease domain that dictate autoactivation Academic Article
- Hypoxia enhances S-nitrosylation-mediated NMDA receptor inhibition via a thiol oxygen sensor motif Academic Article
- Identification and characterization of a novel RNA binding protein that associates with the 5 '-untranslated region of the chloroplast psbA mRNA Academic Article
- Identification and characterization of small molecule antagonists of pRb inactivation by viral oncoproteins Academic Article
- Identification of Gal4 activation domain-binding proteins in the 26S proteasome by periodate-triggered cross-linking Academic Article
- Identification of a motif in the carboxyl terminus of β-arrestin2 responsible for activation of JNK3 Academic Article
- Identification of a novel Mcl-1 protein binding motif Academic Article
- Identification of adenovirus serotype 5 hexon regions that interact with scavenger receptors Academic Article
- Identification of five different Patr class I molecules that bind HLA supertype peptides and definition of their peptide binding motifs Academic Article
- Identification of novel binding elements and gene targets for the homeodomain protein BARX2 Academic Article
- Increasing the receptor tyrosine kinase EphB2 prevents amyloid-β-induced depletion of cell surface glutamate receptors by a mechanism that requires the PDZ-binding motif of EphB2 and neuronal activity Academic Article
- Induction of positive cooperativity by amino acid replacements within the C-terminal domain of penicillium chrysogenum ATP sulfurylase Academic Article
- Insights into substrate specificity of geranylgeranyl reductases revealed by the structure of digeranylgeranylglycerophospholipid reductase, an essential enzyme in the biosynthesis of archaeal membrane lipids Academic Article
- Integrin α(IIb)β(3)-specific synthetic human monoclonal antibodies and HCDR3 peptides that potently inhibit platelet aggregation Academic Article
- Interaction with both ZNRF3 and LGR4 is required for the signalling activity of R-spondin Academic Article
- Interactions between SARS coronavirus and its receptor Academic Article
- Interdependency of brassinosteroid and auxin signaling in Arabidopsis Academic Article
- Interferon-induced transmembrane protein 3 is a type II transmembrane protein Academic Article
- Intrinsically cell-permeable miniature proteins based on a minimal cationic PPII motif Academic Article
- Iron-sulfur cluster engineering provides insight into the evolution of substrate specificity among sulfonucleotide reductases Academic Article
- Iron-sulfur cluster n5 is coordinated by an hxxxcxxcxxxxxc motif in the nuog subunit of escherichia coli nadh : Quinone oxidoreductase (complex i) Academic Article
- Kinetic mechanism of activation of the cdk2/cyclin a complex Academic Article
- Letter to the editor: NMR structure determination of the hypothetical protein TM1290 from Thermotoga maritima using automated NOESY analysis Academic Article
- Ligand access to the active site in thermus thermophilus ba(3) and bovine heart aa(3) cytochrome oxidases Academic Article
- Ligand and coactivator identity determines the requirement of the charge clamp for coactivation of the peroxisome proliferator-activated receptor gamma Academic Article
- Ligand-accelerated Cu-catalyzed azide-alkyne cycloaddition: a mechanistic report Academic Article
- Ligands specify coactivator nuclear receptor (nr) box affinity for estrogen receptor subtypes Academic Article
- Lipidation by the Host Prenyltransferase Machinery Facilitates Membrane Localization of Legionella pneumophila Effector Proteins Academic Article
- Localization of regulatory elements mediating constitutive and cytokine-stimulated plasminogen gene expression Academic Article
- Mechanism of activation of protein kinase JAK2 by the growth hormone receptor Academic Article
- Methylation of the retinoblastoma tumor suppressor by SMYD2 Academic Article
- Minimally cationic cell-permeable miniature proteins via α-helical arginine display Academic Article
- Modulation of allostery by protein intrinsic disorder Academic Article
- Multiple defects in antigen presentation and T cell development by mice expressing cytoplasmic tail-truncated CD1d Academic Article
- Mutational analysis of human eIF4AIII identifies regions necessary for exon junction complex formation and nonsense-mediated mRNA decay Academic Article
- Mutational switching of a yeast tRNA synthetase into a mammalian-like synthetase cytokine Academic Article
- N-(3-oxo-acyl)homoserine lactones signal cell activation through a mechanism distinct from the canonical pathogen-associated molecular pattern recognition receptor pathways Academic Article
- Nascent peptides that block protein synthesis in bacteria Academic Article
- Naturally occurring Phe151Leu substitution near a conserved folding module lowers stability of glutathione transferase P1-1 Academic Article
- Negative regulation of t cell receptor signaling by siglec-7 (p70/airm) and siglec-9 Academic Article
- Neutralizing activity of antibodies to the v3 loop region of hiv-1 gp120 relative to their epitope fine specificity Academic Article
- Nonstimulatory peptides contribute to antigen-induced CD8-T cell receptor interaction at the immunological synapse Academic Article
- Nuclear magnetic resonance structure of a novel globular domain in RBM10 containing OCRE, the octamer repeat sequence motif Academic Article
- On the stability of parainfluenza virus 5 F proteins Academic Article
- Peptoid nanosheets exhibit a new secondary-structure motif Academic Article
- Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST) Academic Article
- Plasmodium circumsporozoite protein promotes the development of the liver stages of the parasite Academic Article
- Plk1- and beta-TrCP-dependent degradation of Bora controls mitotic progression Academic Article
- Positive regulation of ltk ph domain function by soluble ip(4) Academic Article
- Potent inhibitors of lxxll-based protein-protein interactions Academic Article
- Primary infection by a human immunodeficiency virus with atypical coreceptor tropism Academic Article
- Proof of principle for epitope-focused vaccine design Academic Article
- Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins Academic Article
- Proteolytic processing of oligopeptides containing the target sequences by the recombinant tobacco vein mottling virus nia proteinase Academic Article
- Pyrimidone-based series of glucokinase activators with alternative donor-acceptor motif Academic Article
- Quantitative proteomics of the thyroid hormone receptor-coregulator interactions Academic Article
- RAE-1, a novel PHR binding protein, is required for axon termination and synapse formation in Caenorhabditis elegans Academic Article
- RNA recognition by designed peptide fusion creates "artificial" tRNA synthetase Academic Article
- RNF4 interacts with both SUMO and nucleosomes to promote the DNA damage response Academic Article
- Rab-alpha GDI activity is regulated by a Hsp90 chaperone complex Academic Article
- Rad50 zinc hook is important for the Mre11 complex to bind chromosomal DNA double-stranded breaks and initiate various DNA damage responses Academic Article
- Rad50/smc proteins and abc transporters: Unifying concepts from high-resolution structures Academic Article
- Raver1 interactions with vinculin and RNA suggest a feed-forward pathway in directing mRNA to focal adhesions Academic Article
- Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections Academic Article
- Regulation of T cell receptor activation by dynamic membrane binding of the CD3epsilon cytoplasmic tyrosine-based motif Academic Article
- Regulation of the Rhp26(ERCC6/CSB) chromatin remodeler by a novel conserved leucine latch motif Academic Article
- Regulation of the transcriptional coactivator PGC-1 via MAPK-sensitive interaction with a repressor Academic Article
- Relative reactivity of HIV-1 polyclonal plasma antibodies directed to V3 and MPER regions suggests immunodominance of V3 over MPER and dependence of high anti-V3 antibody titers on virus persistence Academic Article
- Requirement of helix 1 and the af-2 domain of the thyroid hormone receptor for coactivation by pgc-1 Academic Article
- Reshaping antibody diversity Academic Article
- Reverse genetics of arenaviruses Academic Article
- Reversible labeling of native and fusion-protein motifs Academic Article
- Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome Academic Article
- S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury Academic Article
- SUMO-binding motifs mediate the Rad60-dependent response to replicative stress and self-association Academic Article
- Selecting improved peptidyl motifs for cytosolic delivery of disparate protein and nanoparticle materials Academic Article
- Selection of silk-binding peptides by phage display Academic Article
- Selective autophagy of BES1 mediated by DSK2 balances plant growth and survival Academic Article
- Self-association of lymphocytic choriomeningitis virus nucleoprotein is mediated by its N-terminal region and is not required for its anti-interferon function Academic Article
- Sequence-specific, nanomolar peptide binding via cucurbit[8]uril-induced folding and inclusion of neighboring side chains Academic Article
- Ser-884 adjacent to the lxxll motif of coactivator trbp defines selectivity for ers and trs Academic Article
- Signals from chloroplasts converge to regulate nuclear gene expression Academic Article
- Single-step inline hydroxyapatite enrichment facilitates identification and quantitation of phosphopeptides from mass-limited proteomes with MudPIT Academic Article
- Site-Specific O-Glycosylation Analysis of SARS-CoV-2 Spike Protein Produced in Insect and Human Cells Academic Article
- Soluble mimetics of human immunodeficiency virus type 1 viral spikes produced by replacement of the native trimerization domain with a heterologous trimerization motif: Characterization and ligand binding analysis Academic Article
- Solution structure of the cysteine-rich domain of the Escherichia coli chaperone protein DnaJ Academic Article
- Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum Academic Article
- Structural and sequence analysis of imelysin-like proteins implicated in bacterial iron uptake Academic Article
- Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16 Academic Article
- Structural basis for hif-1 alpha/cbp recognition in the cellular hypoxic response Academic Article
- Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme cyp11a1 Academic Article
- Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling Academic Article
- Structural basis of substrate methylation and inhibition of SMYD2 Academic Article
- Structural characterization of spo0e-like protein-aspartic acid phosphatases that regulate sporulation in bacilli Academic Article
- Structural features for functional selectivity at serotonin receptors Academic Article
- Structural insights into Nox4 and Nox2: motifs involved in function and cellular localization Academic Article
- Structural mechanism of abscisic acid binding and signaling by dimeric PYR1 Academic Article
- Structural mechanisms of allostery and autoinhibition in JNK family kinases Academic Article
- Structural rationale for the broad neutralization of hiv-1 by human monoclonal antibody 447-52d Academic Article
- Structural switch of lysyl-tRNA synthetase between translation and transcription Academic Article
- Structure and function of a potent agonist for the semi-invariant natural killer T cell receptor Academic Article
- Structure and function of an unusual family of protein phosphatases: the bacterial chemotaxis proteins CheC and CheX Academic Article
- Structure and mechanism of the ruvb holliday junction branch migration motor Academic Article
- Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9 Academic Article
- Structure of Thermotoga maritima TM0439: Implications for the mechanism of bacterial GntR transcription regulators with Zn(2+)-binding FCD domains Academic Article
- Structure of a PE-PPE-EspG complex from Mycobacterium tuberculosis reveals molecular specificity of ESX protein secretion Academic Article
- Structure of a mutant EF-G reveals domain III and possibly the fusidic acid binding site Academic Article
- Structure of botulinurn neurotoxin type d light chain at 1.65 Å resolution: Repercussions for vamp-2 substrate specificity Academic Article
- Structure of full-length Drosophila cryptochrome Academic Article
- Structure of the human smoothened receptor bound to an antitumour agent Academic Article
- Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase Academic Article
- Subclassification and biochemical analysis of plant papain-like cysteine proteases displays subfamily-specific characteristics Academic Article
- Substrate profiling of PRMT1 reveals amino acid sequences that extend beyond the "RGG" paradigm Academic Article
- Substrates of the Arabidopsis thaliana protein isoaspartyl methyltransferase 1 identified using phage display and biopanning Academic Article
- Sulfotransferases: Structure, mechanism, biological activity, inhibition, and synthetic utility Academic Article
- Sumo-targeted ubiquitin ligases in genome stability Academic Article
- Sumoylation regulates nuclear localization of lipin-1 alpha in neuronal cells Academic Article
- Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120 Academic Article
- Survey of immune-related, mannose/fucose-binding c-type lectin receptors reveals widely divergent sugar-binding specificities Academic Article
- Synapse-associated protein-97 isoform-specific regulation of surface AMPA receptors and synaptic function in cultured neurons Academic Article
- Synaptic targeting of n-type calcium channels in hippocampal neurons Academic Article
- Systematic analysis of bacterial effector-postsynaptic density 95/disc large/zonula occludens-1 (PDZ) domain interactions demonstrates Shigella OspE protein promotes protein kinase C activation via PDLIM proteins Academic Article
- Targeted gene knockout by direct delivery of zinc-finger nuclease proteins Academic Article
- Tetrameric architecture of the circadian clock protein KaiB - a novel interface for intermolecular interactions and its impact on the circadian rhythm Academic Article
- The C-Ala domain brings together editing and aminoacylation functions on one tRNA Academic Article
- The I-Ag7 MHC class II molecule linked to murine diabetes is a promiscuous peptide binder Academic Article
- The NS5A protein of hepatitis C virus is a zinc metalloprotein Academic Article
- The PGC-1-related protein PERC is a selective coactivator of estrogen receptor alpha Academic Article
- The RING finger domain of MDM2 is essential for MDM2-mediated TGF-β resistance Academic Article
- The RecQ4 orthologue Hrq1 is critical for DNA interstrand cross-link repair and genome stability in fission yeast Academic Article
- The T cell receptor's α-chain connecting peptide motif promotes close approximation of the CD8 coreceptor allowing efficient signal initiation Academic Article
- The amino acid linker between the endonuclease and helicase domains of adeno-associated virus type 5 Rep plays a critical role in DNA-dependent oligomerization Academic Article
- The clustered protocadherin endolysosomal trafficking motif mediates cytoplasmic association Academic Article
- The coactivator lxxll nuclear receptor recognition motif Academic Article
- The folding and stability of human alpha class glutathione transferase A1-1 depend on distinct roles of a conserved N-capping box and hydrophobic staple motif Academic Article
- The internal ribosome entry site (ires) contained within the rna-binding motif protein 3 (rbm3) mrna is composed of functionally distinct elements Academic Article
- The junctional adhesion molecule JAML is a costimulatory receptor for epithelial gamma delta T cell activation Academic Article
- The maternal gene spn-4 encodes a predicted RRM protein required for mitotic spindle orientation and cell fate patterning in early C. elegans embryos Academic Article
- The molecular mechanisms of coactivator utilization in ligand-dependent transactivation by the androgen receptor Academic Article
- The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis Academic Article
- The rad50 signature motif: Essential to atp binding and biological function Academic Article
- The rad50 zinc-hook is a structure joining mre11 complexes in DNA recombination and repair Academic Article
- The rela nuclear localization signal folds upon binding to i kappa b alpha Academic Article
- The role of stat, ap-1, e-box and tieg motifs in the regulation of hepcidin by il-6 and bmp-9: Lessons from human hamp and murine hamp1 and hamp2 gene promoters Academic Article
- The serine-rich domain from Crk-associated substrate (p130cas) is a four-helix bundle Academic Article
- The structure of Mlc titration factor a (MtfA/YeeI) reveals a prototypical zinc metallopeptidase related to anthrax lethal factor Academic Article
- The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability Academic Article
- The structure of YqeH. An AtNOS1/AtNOA1 ortholog that couples GTP hydrolysis to molecular recognition Academic Article
- The structure of the crispr-associated protein csa3 provides insight into the regulation of the crispr/cas system Academic Article
- The type iii effector espf coordinates membrane trafficking by the spatiotemporal activation of two eukaryotic signaling pathways Academic Article
- The ydaO motif is an ATP-sensing riboswitch in Bacillus subtilis Academic Article
- The z protein of the new world arenavirus tacaribe virus has bona fide budding activity that does not depend on known late domain motifs Academic Article
- Thioether side chain cyclization for helical peptide formation: Inhibitors of estrogen receptor-coactivator interactions Academic Article
- Three-dimensional structure of the ephb2 receptor in complex with an antagonistic peptide reveals a novel mode of inhibition Academic Article
- Tpr-mediated interaction of rapc with coma inhibits response regulator-DNA binding for competence development in bacillus subtilis Academic Article
- Transfer of flexibility between ankyrin repeats in i kappa b alpha upon formation of the nf-kappa b complex Academic Article
- Transferable domain in the g(1) cyclin cln2 sufficient to switch degradation of sic1 from the e3 ubiquitin ligase scfcdc4 to scfgrr1 Academic Article
- Transnitrosylation from DJ-1 to PTEN attenuates neuronal cell death in parkinson's disease models Academic Article
- Two bmp responsive elements, stat, and bzip/hnf4/coup motifs of the hepcidin promoter are critical for bmp, smad1, and hjv responsiveness Academic Article
- Tyrosine phosphorylation controls brassinosteroid receptor activation by triggering membrane release of its kinase inhibitor Academic Article
- Ubiquitin-mediated sequestration of normal cellular proteins into polyglutamine aggregates Academic Article
- Understanding and controlling the metal-directed assembly of terpyridine-functionalized coiled-coil peptides Academic Article
- Unfurling of the band 4.1, ezrin, radixin, moesin (FERM) domain of the merlin tumor suppressor Academic Article
- Vibrio cholerae el tor tcpa crystal structure and mechanism for pilus-mediated microcolony formation Academic Article
- Virus maturation involving large subunit rotations and local refolding Academic Article
- Yaba-like disease virus protein Y144R, a member of the complement control protein family, is present on enveloped virions that are associated with virus-induced actin tails Academic Article
- iRGD tumor-penetrating peptide-modified oncolytic adenovirus shows enhanced tumor transduction, intratumoral dissemination and antitumor efficacy Academic Article