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• 3,4,5-trisubstituted isoxazoles as novel PPAR delta agonists. Part 1  Academic Article
• A cdk-independent function of mammalian cks1: Targeting of scfskp2 to the cdk inhibitor p27(kip1)  Academic Article
• A cell-free biochemical complementation assay reveals complex and redundant cytosolic requirements for lrp endocytosis  Academic Article
• A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis  Academic Article
• A conserved motif in the itk ph-domain is required for phosphoinositide binding and tcr signaling but dispensable for adaptor protein interactions  Academic Article
• A five-amino-acid motif in the undefined region of the tlr8 ectodomain is required for species-specific ligand recognition  Academic Article
• A free terminal carboxylate group is required for phra pentapeptide inhibition of rapa phosphatase  Academic Article
• A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2g12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120  Academic Article
• A highly conserved arginine in gp120 governs HIV-1 binding to both syndecans and CCR5 via sulfated motifs  Academic Article
• A method for defining binding sites involved in protein-protein interactions: analysis of the binding of plasminogen activator inhibitor 1 to the somatomedin domain of vitronectin  Academic Article
• A new family of aspartyl phosphate phosphatases targeting the sporulation transcription factor spo0a of bacillus subtilis  Academic Article
• A new functional domain of guanine nucleotide dissociation inhibitor (alpha-gdi) involved in rab recycling  Academic Article
• A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase  Academic Article
• A novel loop-loop recognition motif in the yeast ribosomal protein L30 autoregulatory RNA complex  Academic Article
• A peptide core motif for binding to heterotrimeric G protein α subunits  Academic Article
• A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin  Academic Article
• A role for peroxisomes in photomorphogenesis and development of Arabidopsis  Academic Article
• A structural framework for deciphering the link between I-A(g7) and autoimmune diabetes  Academic Article
• ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1  Academic Article
• Aak1-mediated mu 2 phosphorylation is stimulated by assembled clathrin  Academic Article
• Adenovirus serotype 5 fiber shaft influences in vivo gene transfer in mice  Academic Article
• Alanyl-tRNA synthetase crystal structure and design for acceptor-stem recognition  Academic Article
• Alternative chemistries for the synthesis of thrombospondin-1 type 1 repeats  Academic Article
• Alternative splicing of a beta4 subunit proline-rich motif regulates voltage-dependent gating and toxin block of Ca(v)2.1 Ca2+ channels  Academic Article
• An EB1-binding motif acts as a microtubule tip localization signal  Academic Article
• An evolutionary perspective on eukaryotic membrane trafficking  Academic Article
• Anti-Gag cytolytic T lymphocytes specific for an alternative translational reading frame-derived epitope and resistance versus susceptibility to retrovirus-induced murine AIDS in F(1) mice  Academic Article
• Antigen recognition by variable lymphocyte receptors  Academic Article
• Apparent loss-of-function mutant GPCRs revealed as constitutively desensitized receptors  Academic Article
• Aromatic amino acids providing characteristic motifs in the Raman and SERS spectroscopy of peptides  Academic Article
• Association of p130(cas) with phosphatidylinositol-3-oh kinase mediates adenovirus cell entry  Academic Article
• Biarsenical-tetracysteine motif as a fluorescent tag for detection in capillary electrophoresis  Academic Article
• Biochemistry. Ubiquitination - more than two to tango  Academic Article
• Blmiii and bimiv nonribosornal peptide synthetase-catalyzed biosynthesis of the bleomycin bithiazole moiety involving both in cis and in trans aminoacylation  Academic Article
• Broadly neutralizing anti-hiv antibody 4e10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41  Academic Article
• Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41  Academic Article
• CPSF30 and Wdr33 directly bind to AAUAAA in mammalian mRNA 3 ' processing  Academic Article
• Casein kinase-2 mediates cell survival through phosphorylation and degradation of inositol hexakisphosphate kinase-2  Academic Article
• Cataracts and microphthalmia caused by a Gja8 mutation in extracellular loop 2  Academic Article
• Changes in active site histidine hydrogen bonding trigger cryptochrome activation  Academic Article
• Characterization of the iron-sulfur cluster n7 (n1c) in the subunit nuog of the proton-translocating nadh-quinone oxidoreductase from escherichia coli  Academic Article
• Cip1 and Cip2 are novel RNA-recognition-motif proteins that counteract Csx1 function during oxidative stress  Academic Article
• Circadian clock activity of cryptochrome relies on tryptophan-mediated photoreduction  Academic Article
• Cloning of the Arabidopsis clock cone TOC1, an autoregulatory response regulator homolog  Academic Article
• Co-folding of a FliF-FliG split domain forms the basis of the MS:C ring interface within the bacterial flagellar motor  Academic Article
• Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold  Academic Article
• Computational design of high-affinity epitope scaffolds by backbone grafting of a linear epitope  Academic Article
• Conformational flexibility in crystal structures of human 11 β-hydroxysteroid dehydrogenase type I provide insights into glucocorticoid interconversion and enzyme regulation  Academic Article
• Conserved cysteines in the sialyltransferase sialylmotifs form an essential disulfide bond  Academic Article
• Conserved xpb core structure and motifs for DNA unwinding: Implications for pathway selection of transcription or excision repair  Academic Article
• Constitutive nadph oxidase 4 activity resides in the composition of the b-loop and the penultimate c terminus  Academic Article
• Contribution of glycine 146 to a conserved folding module affecting stability and refolding of human glutathione transferase P1-1  Academic Article
• Crystal structure and novel recognition motif of rho adp-ribosylating c3 exoenzyme from clostridium botulinum: Structural insights for recognition specificity and catalysis  Academic Article
• Crystal structure of NMA 1982 from Neisseria meningiddis at 1.5 Å resolution provides a structural scaffold for nonclassical, eukaryotic-like phosphatases  Academic Article
• Crystal structure of a human aminoacyl-tRNA synthetase cytokine  Academic Article
• Crystal structure of botulinum neurotoxin type g light chain: Serotype divergence in substrate recognition  Academic Article
• Crystal structure of full-length Zika virus NS5 protein reveals a conformation similar to Japanese encephalitis virus NS5  Academic Article
• Crystal structure of human toll-like receptor 3 (tlr3) ectodomain  Academic Article
• Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain  Academic Article
• Crystal structure of the Fic (Filamentation induced by cAMP) family protein SO4266 (gi|24375750) from Shewanella oneidensis MR-1 at 1.6 A resolution  Academic Article
• Crystal structures of two novel dye-decolorizing peroxidases reveal a β-barrel fold with a conserved heme-binding motif  Academic Article
• CtIP protein dimerization is critical for its recruitment to chromosomal DNA double-stranded breaks  Academic Article
• Cystinosin, the protein defective in cystinosis, is a h+-driven lysosomal cystine transporter  Academic Article
• DNA binding and nucleotide flipping by the human DNA repair protein agt  Academic Article
• DNA binding domain in the replication checkpoint protein Mrc1 of Schizosaccharomyces pombe  Academic Article
• Deciphering the role of histidine 252 in mycobacterial adenosine 5'-phosphosulfate (APS) reductase catalysis  Academic Article
• Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors  Academic Article
• Design, synthesis, and biological evaluation of hiv/fiv protease inhibitors incorporating a conformationally constrained macrocycle with a small p3 ' residue  Academic Article
• Detailed characterization of the peptide binding specificity of five common Patr class I MHC molecules  Academic Article
• Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis  Academic Article
• Determinants of the heme-CO vibrational modes in the H-NOX family  Academic Article
• Di-acidic motifs in the membrane-distal C termini modulate the transport of angiotensin II receptors from the endoplasmic reticulum to the cell surface  Academic Article
• Dissociating quaternary structure regulates cell-signaling functions of a secreted human tRNA synthetase  Academic Article
• Distinct domains of tRNA synthetase recognize the same base pair  Academic Article
• Distinct mechanisms control the stability of the related s-phase cyclins clb5 and clb6  Academic Article
• Distinct protein classes including novel merozoite surface antigens in Raft-like membranes of Plasmodium falciparum  Academic Article
• Disulfide-bond formation by a single cysteine mutation in adenovirus protein vi impairs capsid release and membrane lysis  Academic Article
• Drosophila TRF2 is a preferential core promoter regulator  Academic Article
• Dual recruitment of Cdc48 (p97)-Ufd1-Npl4 ubiquitin-selective segregase by small ubiquitin-like modifier protein (SUMO) and ubiquitin in SUMO-targeted ubiquitin ligase-mediated genome stability functions  Academic Article
• Dual roles for an arginine-rich motif in specific genome recognition and localization of viral coat protein to rna replication sites in flock house virus-infected cells  Academic Article
• E3 ubiquitin-protein ligase activity of Parkin is dependent on cooperative interaction of RING finger (TRIAD) elements  Academic Article
• Engineered mutations change the structure and stability of a virus-like particle  Academic Article
• Envelope diversity, characteristics of V3 region and predicted co-receptor usage of human immunodeficiency viruses infecting north Indians  Academic Article
• Eukaryotic class II cyclobutane pyrimidine dimer photolyase structure reveals basis for improved ultraviolet tolerance in plants  Academic Article
• Evidence that YycJ is a novel 5 '-3 ' double-stranded DNA exonuclease acting in Bacillus anthracis mismatch repair  Academic Article
• Evolution of the hemagglutinin protein of the new pandemic H1N1 influenza virus: maintaining optimal receptor binding by compensatory substitutions  Academic Article
• Evolutionary and taxonomic implications of conserved structural motifs between picornaviruses and insect picorna-like viruses  Academic Article
• Exploring the repeat protein universe through computational protein design  Academic Article
• Fast dynamics of HP35 for folded and urea-unfolded conditions  Academic Article
• Fine mapping of murine antibody responses to immunization with a novel soluble form of hepatitis C virus envelope glycoprotein complex  Academic Article
• From benchmarking HITS-CLIP peak detection programs to a new method for identification of miRNA-binding sites from Ago2-CLIP data  Academic Article
• Functional advantages of dynamic protein disorder  Academic Article
• GC-GAP, a Rho family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2  Academic Article
• GIPC is recruited by APPL to peripheral TrkA endosomes and regulates TrkA trafficking and signaling  Academic Article
• GSK3beta phosphorylation modulates CLASP-microtubule association and lamella microtubule attachment  Academic Article
• Gain-of-function mutational activation of human tRNA synthetase procytokine  Academic Article
• Genetic and biochemical evidence for an oligomeric structure of the functional L polymerase of the prototypic arenavirus lymphocytic choriomeningitis virus  Academic Article
• Genetically encoded fragment-based discovery of glycopeptide ligands for carbohydrate-binding proteins  Academic Article
• Genomic-scale comparison of sequence- and structure-based methods of function prediction: Does structure provide additional insight?  Academic Article
• Genomics, evolution, and crystal structure of a new family of bacterial spore kinases  Academic Article
• Glycation of the amyloid beta-protein by a nicotine metabolite: A fortuitous chemical dynamic between smoking and Alzheimer's disease  Academic Article
• HSP90 regulates cell survival via inositol hexakisphosphate kinase-2  Academic Article
• Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger  Academic Article
• Helical domain and kinase domain mutations in p110 alpha of phosphatidylinositol 3-kinase induce gain of function by different mechanisms  Academic Article
• Heparin antagonism by polyvalent display of cationic motifs on virus-like particles  Academic Article
• Highly selective cyclic peptide ligands for NeutrAvidin and avidin identified by phage display  Academic Article
• Homo-oligomerization is the essential function of the tandem BRCT domains in the checkpoint protein Crb2  Academic Article
• Human abh3 structure and key residues for oxidative demethylation to reverse DNA/rna damage  Academic Article
• Human/chicken urokinase chimeras demonstrate sequences outside the serine protease domain that dictate autoactivation  Academic Article
• Hypoxia enhances S-nitrosylation-mediated NMDA receptor inhibition via a thiol oxygen sensor motif  Academic Article
• Identification and characterization of a novel RNA binding protein that associates with the 5 '-untranslated region of the chloroplast psbA mRNA  Academic Article
• Identification and characterization of small molecule antagonists of pRb inactivation by viral oncoproteins  Academic Article
• Identification of Gal4 activation domain-binding proteins in the 26S proteasome by periodate-triggered cross-linking  Academic Article
• Identification of a motif in the carboxyl terminus of β-arrestin2 responsible for activation of JNK3  Academic Article
• Identification of a novel Mcl-1 protein binding motif  Academic Article
• Identification of adenovirus serotype 5 hexon regions that interact with scavenger receptors  Academic Article
• Identification of five different Patr class I molecules that bind HLA supertype peptides and definition of their peptide binding motifs  Academic Article
• Identification of novel binding elements and gene targets for the homeodomain protein BARX2  Academic Article
• Increasing the receptor tyrosine kinase EphB2 prevents amyloid-β-induced depletion of cell surface glutamate receptors by a mechanism that requires the PDZ-binding motif of EphB2 and neuronal activity  Academic Article
• Induction of positive cooperativity by amino acid replacements within the C-terminal domain of penicillium chrysogenum ATP sulfurylase  Academic Article
• Insights into substrate specificity of geranylgeranyl reductases revealed by the structure of digeranylgeranylglycerophospholipid reductase, an essential enzyme in the biosynthesis of archaeal membrane lipids  Academic Article
• Integrin α(IIb)β(3)-specific synthetic human monoclonal antibodies and HCDR3 peptides that potently inhibit platelet aggregation  Academic Article
• Interaction with both ZNRF3 and LGR4 is required for the signalling activity of R-spondin  Academic Article
• Interactions between SARS coronavirus and its receptor  Academic Article
• Interdependency of brassinosteroid and auxin signaling in Arabidopsis  Academic Article
• Interferon-induced transmembrane protein 3 is a type II transmembrane protein  Academic Article
• Intrinsically cell-permeable miniature proteins based on a minimal cationic PPII motif  Academic Article
• Iron-sulfur cluster engineering provides insight into the evolution of substrate specificity among sulfonucleotide reductases  Academic Article
• Iron-sulfur cluster n5 is coordinated by an hxxxcxxcxxxxxc motif in the nuog subunit of escherichia coli nadh : Quinone oxidoreductase (complex i)  Academic Article
• Kinetic mechanism of activation of the cdk2/cyclin a complex  Academic Article
• Letter to the editor: NMR structure determination of the hypothetical protein TM1290 from Thermotoga maritima using automated NOESY analysis  Academic Article
• Ligand access to the active site in thermus thermophilus ba(3) and bovine heart aa(3) cytochrome oxidases  Academic Article
• Ligand and coactivator identity determines the requirement of the charge clamp for coactivation of the peroxisome proliferator-activated receptor gamma  Academic Article
• Ligand-accelerated Cu-catalyzed azide-alkyne cycloaddition: a mechanistic report  Academic Article
• Ligands specify coactivator nuclear receptor (nr) box affinity for estrogen receptor subtypes  Academic Article
• Lipidation by the Host Prenyltransferase Machinery Facilitates Membrane Localization of Legionella pneumophila Effector Proteins  Academic Article
• Localization of regulatory elements mediating constitutive and cytokine-stimulated plasminogen gene expression  Academic Article
• Mechanism of activation of protein kinase JAK2 by the growth hormone receptor  Academic Article
• Methylation of the retinoblastoma tumor suppressor by SMYD2  Academic Article
• Minimally cationic cell-permeable miniature proteins via α-helical arginine display  Academic Article
• Modulation of allostery by protein intrinsic disorder  Academic Article
• Multiple defects in antigen presentation and T cell development by mice expressing cytoplasmic tail-truncated CD1d  Academic Article
• Mutational analysis of human eIF4AIII identifies regions necessary for exon junction complex formation and nonsense-mediated mRNA decay  Academic Article
• Mutational switching of a yeast tRNA synthetase into a mammalian-like synthetase cytokine  Academic Article
• N-(3-oxo-acyl)homoserine lactones signal cell activation through a mechanism distinct from the canonical pathogen-associated molecular pattern recognition receptor pathways  Academic Article
• Nascent peptides that block protein synthesis in bacteria  Academic Article
• Naturally occurring Phe151Leu substitution near a conserved folding module lowers stability of glutathione transferase P1-1  Academic Article
• Negative regulation of t cell receptor signaling by siglec-7 (p70/airm) and siglec-9  Academic Article
• Neutralizing activity of antibodies to the v3 loop region of hiv-1 gp120 relative to their epitope fine specificity  Academic Article
• Nonstimulatory peptides contribute to antigen-induced CD8-T cell receptor interaction at the immunological synapse  Academic Article
• Nuclear magnetic resonance structure of a novel globular domain in RBM10 containing OCRE, the octamer repeat sequence motif  Academic Article
• On the stability of parainfluenza virus 5 F proteins  Academic Article
• Peptoid nanosheets exhibit a new secondary-structure motif  Academic Article
• Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST)  Academic Article
• Plasmodium circumsporozoite protein promotes the development of the liver stages of the parasite  Academic Article
• Plk1- and beta-TrCP-dependent degradation of Bora controls mitotic progression  Academic Article
• Positive regulation of ltk ph domain function by soluble ip(4)  Academic Article
• Potent inhibitors of lxxll-based protein-protein interactions  Academic Article
• Primary infection by a human immunodeficiency virus with atypical coreceptor tropism  Academic Article
• Proof of principle for epitope-focused vaccine design  Academic Article
• Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins  Academic Article
• Proteolytic processing of oligopeptides containing the target sequences by the recombinant tobacco vein mottling virus nia proteinase  Academic Article
• Pyrimidone-based series of glucokinase activators with alternative donor-acceptor motif  Academic Article
• Quantitative proteomics of the thyroid hormone receptor-coregulator interactions  Academic Article
• RAE-1, a novel PHR binding protein, is required for axon termination and synapse formation in Caenorhabditis elegans  Academic Article
• RNA recognition by designed peptide fusion creates "artificial" tRNA synthetase  Academic Article
• RNF4 interacts with both SUMO and nucleosomes to promote the DNA damage response  Academic Article
• Rab-alpha GDI activity is regulated by a Hsp90 chaperone complex  Academic Article
• Rad50 zinc hook is important for the Mre11 complex to bind chromosomal DNA double-stranded breaks and initiate various DNA damage responses  Academic Article
• Rad50/smc proteins and abc transporters: Unifying concepts from high-resolution structures  Academic Article
• Raver1 interactions with vinculin and RNA suggest a feed-forward pathway in directing mRNA to focal adhesions  Academic Article
• Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections  Academic Article
• Regulation of T cell receptor activation by dynamic membrane binding of the CD3epsilon cytoplasmic tyrosine-based motif  Academic Article
• Regulation of the Rhp26(ERCC6/CSB) chromatin remodeler by a novel conserved leucine latch motif  Academic Article
• Regulation of the transcriptional coactivator PGC-1 via MAPK-sensitive interaction with a repressor  Academic Article
• Relative reactivity of HIV-1 polyclonal plasma antibodies directed to V3 and MPER regions suggests immunodominance of V3 over MPER and dependence of high anti-V3 antibody titers on virus persistence  Academic Article
• Requirement of helix 1 and the af-2 domain of the thyroid hormone receptor for coactivation by pgc-1  Academic Article
• Reshaping antibody diversity  Academic Article
• Reverse genetics of arenaviruses  Academic Article
• Reversible labeling of native and fusion-protein motifs  Academic Article
• Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome  Academic Article
• S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury  Academic Article
• SUMO-binding motifs mediate the Rad60-dependent response to replicative stress and self-association  Academic Article
• Selecting improved peptidyl motifs for cytosolic delivery of disparate protein and nanoparticle materials  Academic Article
• Selection of silk-binding peptides by phage display  Academic Article
• Selective autophagy of BES1 mediated by DSK2 balances plant growth and survival  Academic Article
• Self-association of lymphocytic choriomeningitis virus nucleoprotein is mediated by its N-terminal region and is not required for its anti-interferon function  Academic Article
• Sequence-specific, nanomolar peptide binding via cucurbit[8]uril-induced folding and inclusion of neighboring side chains  Academic Article
• Ser-884 adjacent to the lxxll motif of coactivator trbp defines selectivity for ers and trs  Academic Article
• Signals from chloroplasts converge to regulate nuclear gene expression  Academic Article
• Single-step inline hydroxyapatite enrichment facilitates identification and quantitation of phosphopeptides from mass-limited proteomes with MudPIT  Academic Article
• Site-Specific O-Glycosylation Analysis of SARS-CoV-2 Spike Protein Produced in Insect and Human Cells  Academic Article
• Soluble mimetics of human immunodeficiency virus type 1 viral spikes produced by replacement of the native trimerization domain with a heterologous trimerization motif: Characterization and ligand binding analysis  Academic Article
• Solution structure of the cysteine-rich domain of the Escherichia coli chaperone protein DnaJ  Academic Article
• Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum  Academic Article
• Structural and sequence analysis of imelysin-like proteins implicated in bacterial iron uptake  Academic Article
• Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16  Academic Article
• Structural basis for hif-1 alpha/cbp recognition in the cellular hypoxic response  Academic Article
• Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme cyp11a1  Academic Article
• Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling  Academic Article
• Structural basis of substrate methylation and inhibition of SMYD2  Academic Article
• Structural characterization of spo0e-like protein-aspartic acid phosphatases that regulate sporulation in bacilli  Academic Article
• Structural features for functional selectivity at serotonin receptors  Academic Article
• Structural insights into Nox4 and Nox2: motifs involved in function and cellular localization  Academic Article
• Structural mechanism of abscisic acid binding and signaling by dimeric PYR1  Academic Article
• Structural mechanisms of allostery and autoinhibition in JNK family kinases  Academic Article
• Structural rationale for the broad neutralization of hiv-1 by human monoclonal antibody 447-52d  Academic Article
• Structural switch of lysyl-tRNA synthetase between translation and transcription  Academic Article
• Structure and function of a potent agonist for the semi-invariant natural killer T cell receptor  Academic Article
• Structure and function of an unusual family of protein phosphatases: the bacterial chemotaxis proteins CheC and CheX  Academic Article
• Structure and mechanism of the ruvb holliday junction branch migration motor  Academic Article
• Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9  Academic Article
• Structure of Thermotoga maritima TM0439: Implications for the mechanism of bacterial GntR transcription regulators with Zn(2+)-binding FCD domains  Academic Article
• Structure of a PE-PPE-EspG complex from Mycobacterium tuberculosis reveals molecular specificity of ESX protein secretion  Academic Article
• Structure of a mutant EF-G reveals domain III and possibly the fusidic acid binding site  Academic Article
• Structure of botulinurn neurotoxin type d light chain at 1.65 Å resolution: Repercussions for vamp-2 substrate specificity  Academic Article
• Structure of full-length Drosophila cryptochrome  Academic Article
• Structure of the human smoothened receptor bound to an antitumour agent  Academic Article
• Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase  Academic Article
• Subclassification and biochemical analysis of plant papain-like cysteine proteases displays subfamily-specific characteristics  Academic Article
• Substrate profiling of PRMT1 reveals amino acid sequences that extend beyond the "RGG" paradigm  Academic Article
• Substrates of the Arabidopsis thaliana protein isoaspartyl methyltransferase 1 identified using phage display and biopanning  Academic Article
• Sulfotransferases: Structure, mechanism, biological activity, inhibition, and synthetic utility  Academic Article
• Sumo-targeted ubiquitin ligases in genome stability  Academic Article
• Sumoylation regulates nuclear localization of lipin-1 alpha in neuronal cells  Academic Article
• Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120  Academic Article
• Survey of immune-related, mannose/fucose-binding c-type lectin receptors reveals widely divergent sugar-binding specificities  Academic Article
• Synapse-associated protein-97 isoform-specific regulation of surface AMPA receptors and synaptic function in cultured neurons  Academic Article
• Synaptic targeting of n-type calcium channels in hippocampal neurons  Academic Article
• Systematic analysis of bacterial effector-postsynaptic density 95/disc large/zonula occludens-1 (PDZ) domain interactions demonstrates Shigella OspE protein promotes protein kinase C activation via PDLIM proteins  Academic Article
• Targeted gene knockout by direct delivery of zinc-finger nuclease proteins  Academic Article
• Tetrameric architecture of the circadian clock protein KaiB - a novel interface for intermolecular interactions and its impact on the circadian rhythm  Academic Article
• The C-Ala domain brings together editing and aminoacylation functions on one tRNA  Academic Article
• The I-Ag7 MHC class II molecule linked to murine diabetes is a promiscuous peptide binder  Academic Article
• The NS5A protein of hepatitis C virus is a zinc metalloprotein  Academic Article
• The PGC-1-related protein PERC is a selective coactivator of estrogen receptor alpha  Academic Article
• The RING finger domain of MDM2 is essential for MDM2-mediated TGF-β resistance  Academic Article
• The RecQ4 orthologue Hrq1 is critical for DNA interstrand cross-link repair and genome stability in fission yeast  Academic Article
• The T cell receptor's α-chain connecting peptide motif promotes close approximation of the CD8 coreceptor allowing efficient signal initiation  Academic Article
• The amino acid linker between the endonuclease and helicase domains of adeno-associated virus type 5 Rep plays a critical role in DNA-dependent oligomerization  Academic Article
• The clustered protocadherin endolysosomal trafficking motif mediates cytoplasmic association  Academic Article
• The coactivator lxxll nuclear receptor recognition motif  Academic Article
• The folding and stability of human alpha class glutathione transferase A1-1 depend on distinct roles of a conserved N-capping box and hydrophobic staple motif  Academic Article
• The internal ribosome entry site (ires) contained within the rna-binding motif protein 3 (rbm3) mrna is composed of functionally distinct elements  Academic Article
• The junctional adhesion molecule JAML is a costimulatory receptor for epithelial gamma delta T cell activation  Academic Article
• The maternal gene spn-4 encodes a predicted RRM protein required for mitotic spindle orientation and cell fate patterning in early C. elegans embryos  Academic Article
• The molecular mechanisms of coactivator utilization in ligand-dependent transactivation by the androgen receptor  Academic Article
• The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis  Academic Article
• The rad50 signature motif: Essential to atp binding and biological function  Academic Article
• The rad50 zinc-hook is a structure joining mre11 complexes in DNA recombination and repair  Academic Article
• The rela nuclear localization signal folds upon binding to i kappa b alpha  Academic Article
• The role of stat, ap-1, e-box and tieg motifs in the regulation of hepcidin by il-6 and bmp-9: Lessons from human hamp and murine hamp1 and hamp2 gene promoters  Academic Article
• The serine-rich domain from Crk-associated substrate (p130cas) is a four-helix bundle  Academic Article
• The structure of Mlc titration factor a (MtfA/YeeI) reveals a prototypical zinc metallopeptidase related to anthrax lethal factor  Academic Article
• The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability  Academic Article
• The structure of YqeH. An AtNOS1/AtNOA1 ortholog that couples GTP hydrolysis to molecular recognition  Academic Article
• The structure of the crispr-associated protein csa3 provides insight into the regulation of the crispr/cas system  Academic Article
• The type iii effector espf coordinates membrane trafficking by the spatiotemporal activation of two eukaryotic signaling pathways  Academic Article
• The ydaO motif is an ATP-sensing riboswitch in Bacillus subtilis  Academic Article
• The z protein of the new world arenavirus tacaribe virus has bona fide budding activity that does not depend on known late domain motifs  Academic Article
• Thioether side chain cyclization for helical peptide formation: Inhibitors of estrogen receptor-coactivator interactions  Academic Article
• Three-dimensional structure of the ephb2 receptor in complex with an antagonistic peptide reveals a novel mode of inhibition  Academic Article
• Tpr-mediated interaction of rapc with coma inhibits response regulator-DNA binding for competence development in bacillus subtilis  Academic Article
• Transfer of flexibility between ankyrin repeats in i kappa b alpha upon formation of the nf-kappa b complex  Academic Article
• Transferable domain in the g(1) cyclin cln2 sufficient to switch degradation of sic1 from the e3 ubiquitin ligase scfcdc4 to scfgrr1  Academic Article
• Transnitrosylation from DJ-1 to PTEN attenuates neuronal cell death in parkinson's disease models  Academic Article
• Two bmp responsive elements, stat, and bzip/hnf4/coup motifs of the hepcidin promoter are critical for bmp, smad1, and hjv responsiveness  Academic Article
• Tyrosine phosphorylation controls brassinosteroid receptor activation by triggering membrane release of its kinase inhibitor  Academic Article
• Ubiquitin-mediated sequestration of normal cellular proteins into polyglutamine aggregates  Academic Article
• Understanding and controlling the metal-directed assembly of terpyridine-functionalized coiled-coil peptides  Academic Article
• Unfurling of the band 4.1, ezrin, radixin, moesin (FERM) domain of the merlin tumor suppressor  Academic Article
• Vibrio cholerae el tor tcpa crystal structure and mechanism for pilus-mediated microcolony formation  Academic Article
• Virus maturation involving large subunit rotations and local refolding  Academic Article
• Yaba-like disease virus protein Y144R, a member of the complement control protein family, is present on enveloped virions that are associated with virus-induced actin tails  Academic Article
• iRGD tumor-penetrating peptide-modified oncolytic adenovirus shows enhanced tumor transduction, intratumoral dissemination and antitumor efficacy  Academic Article