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Gelatinases

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  • Cloning of a 72 kda matrix metalloproteinase (gelatinase) from chicken-embryo fibroblasts using gene family pcr - expression of the gelatinase increases upon malignant transformation  Academic Article
  • Cloning, expression, and characterization of chicken tissue inhibitor of metalloproteinase-2 (timp-2) in normal and transformed chicken embryo fibroblasts  Academic Article
  • Disruption of angiogenesis by pex, a noncatalytic metalloproteinase fragment with integrin binding activity  Academic Article
  • Fibroblast activation protein alpha is expressed by chondrocytes following a pro-inflammatory stimulus and is elevated in osteoarthritis  Academic Article
  • Full activation of enterococcus faecalis gelatinase by a c-terminal proteolytic cleavage  Academic Article
  • Functional activation of integrin αvβ3 in tumor cells expressing membrane-type 1 matrix metalloproteinase  Academic Article
  • Gelatinase activity imaged by activatable cell-penetrating peptides in cell-based and in vivo models of stroke  Academic Article
  • Isolation and characterization of a 70-kda metalloprotease (gelatinase) that is elevated in rous-sarcoma virus-transformed chicken-embryo fibroblasts  Academic Article
  • Localization of matrix metalloproteinase mmp-2 to the surface of invasive cells by interaction with integrin alpha v beta 3  Academic Article
  • MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs  Academic Article
  • Matrix metalloproteases of the developing sea urchin embryo  Academic Article
  • Matrix metalloproteinase-2 activation modulates glioma cell migration  Academic Article
  • Matrix metalloproteinase-2 is an interstitial collagenase. Inhibitor-free enzyme catalyzes the cleavage of collagen fibrils and soluble native type I collagen generating the specific 3/4- and 1/4-length fragments  Academic Article
  • Matrix metalloproteinases increase very early during experimental focal cerebral ischemia  Academic Article
  • Microglial cell activation is a source of metalloproteinase generation during hemorrhagic transformation  Academic Article
  • Native timp-free 70-kda progelatinase (mmp-2) secreted at elevated levels by rsv transformed fibroblasts  Academic Article
  • Overexpression of legumain in tumors is significant for invasion/metastasis and a candidate enzymatic target for prodrug therapy  Academic Article
  • Proyl peptidases: a serine protease subfamily with high potential for drug discovery  Academic Article
  • Regulation of neutrophil and eosinophil secondary granule gene expression by transcription factors C/EBP epsilon and PU.1  Academic Article
  • Remodeling of collagen matrix by human tumor cells requires activation and cell surface association of matrix metalloproteinase-2  Academic Article
  • Serine protease and metallo protease cascade systems involved in pericellular proteolysis  Academic Article
  • Synthesis and structure-activity relationship of N-alkyl Gly-boro-Pro inhibitors of DPP4, FAP, and DPP7  Academic Article
  • Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice  Academic Article
  • Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake  Academic Article
  • The enterococcus faecalis fsr two-component system controls biofilm development through production of gelatinase  Academic Article
  • Tumor cell invasion through matrigel is regulated by activated matrix metalloproteinase-2  Academic Article
  • Tumor promoter-stimulated mr92,000 gelatinase secreted by normal and malignant human-cells - isolation and characterization of the enzyme from ht1080 tumor-cells  Academic Article
  • What structure and function of avian plasminogen activator and matrix metalloproteinase-2 reveal about their counterpart mammalian enzymes, their regulation and their role in tumor invasion  Academic Article

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