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Receptors, Nicotinic

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  • A novel α2/α4 subtype-selective positive allosteric modulator of nicotinic acetylcholine receptors acting from the C-tail of an α subunit  Academic Article
  • Acetylarsenocholine: a cholinergic agonist  Academic Article
  • Acetylcholine receptor channel imaged in the open state  Academic Article
  • Activation of the alpha7 nAChR reduces acid-induced acute lung injury in mice and rats  Academic Article
  • Activation of the nicotinic acetylcholine receptor involves a switch in conformation of the a subunits  Academic Article
  • Agonist-induced closure of constitutively open gamma-aminobutyric acid channels with mutated M2 domains  Academic Article
  • Altered activity-rest patterns in mice with a human autosomal-dominant nocturnal frontal lobe epilepsy mutation in the β2 nicotinic receptor  Academic Article
  • Amino-terminal sequence of the 40000 molecular-weight subunit of the acetylcholine-receptor protein from torpedo-marmorata  Academic Article
  • An accessory agonist binding site promotes activation of α4β2* nicotinic acetylcholine receptors  Academic Article
  • An ion selectivity filter in the extracellular domain of Cys-loop receptors reveals determinants for ion conductance  Academic Article
  • Anti-acetylcholine receptor fab fragments isolated from thymus-derived phage display libraries from myasthenia gravis patients reflect predominant specificities in serum and block the action of pathogenic serum antibodies  Academic Article
  • Arrangement of the acetylcholine-receptor subunits in the resting and desensitized states, determined by cryoelectron microscopy of crystallized torpedo postsynaptic membranes  Academic Article
  • Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss  Academic Article
  • Biophysical and ion channel functional characterization of the torpedo californica nicotinic acetylcholine receptor in varying detergent-lipid environments  Academic Article
  • Blockade of nicotine self-administration with nicotinic antagonists in rats  Academic Article
  • Blockade of nicotinic responses in rat retinal ganglion cells by neuronal bungarotoxin  Academic Article
  • CHRNA5 and CHRNA3 variants and level of neuroticism in young adult Mexican American men and women  Academic Article
  • Catecholamine release-inhibitory peptide catestatin (chromogranin a(352-372)) - naturally occurring amino acid variant gly364ser causes profound changes in human autonomic activity and alters risk for hypertension  Academic Article
  • Characterization of nicotinic receptors in chick retina using a snake venom neurotoxin that blocks neuronal nicotinic receptor function  Academic Article
  • Chronic nicotine treatment counteracts dopamine d-2 receptor up-regulation induced by a partial meso-diencephalic hemitransection in the rat  Academic Article
  • Coaxing a pyridine nucleus to give up its aromaticity: synthesis and pharmacological characterization of novel conformationally restricted analogues of nicotine and anabasine  Academic Article
  • Colocalization of muscarinic and nicotinic receptors in cholinoceptive neurons of the suprachiasmatic region in young and aged rats  Academic Article
  • Contemporary paradigms for cholinergic ligand design guided by biological structure  Academic Article
  • Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors  Academic Article
  • Cyclic AMP and the nicotinic response of bovine adrenal chromaffin cells  Academic Article
  • Development of novel pharmacotherapeutics for tobacco dependence: Progress and future directions  Academic Article
  • Differential effects of nerve transection on the ACh and GABA receptors of chick ciliary ganglion neurons  Academic Article
  • Effects of the specific alpha 4 beta 2 nachr antagonist, 2-fluoro-3-(4-nitrophenyl) deschloroepibatidine, on nicotine reward-related behaviors in rats and mice  Academic Article
  • Electron microscopic evidence for the assembly of soluble pentameric extracellular domains of the nicotinic acetylcholine receptor  Academic Article
  • Evidence for a complex influence of nicotinic acetylcholine receptors on hippocampal serotonin release  Academic Article
  • Fluorinated pyrazole acids are agonists of the high affinity niacin receptor GPR109a  Academic Article
  • Galanthamine and non-competitive inhibitor binding to ACh-binding protein: evidence for a binding site on non-alpha-subunit interfaces of heteromeric neuronal nicotinic receptors  Academic Article
  • Generation of candidate ligands for nicotinic acetylcholine receptors via in situ click chemistry with a soluble acetylcholine binding protein template  Academic Article
  • Habenular alpha 5 nicotinic receptor subunit signalling controls nicotine intake  Academic Article
  • Human anti-nicotinic acetylcholine receptor recombinant fab fragments isolated from thymus-derived phage display libraries from myasthenia gravis patients reflect predominant specificities in serum and block the action of pathogenic serum antibodies  Academic Article
  • Human cortical-neurons contain both nicotinic and muscarinic acetylcholine-receptors - an immunocytochemical double-labeling study  Academic Article
  • Identification and characterization of novel nicotinic receptor-associated proteins in Caenorhabditis elegans  Academic Article
  • Immunological cross-reactivity between mimicking epitopes on a virus protein and a human autoantigen depends on a single amino-acid residue  Academic Article
  • Light-induced calcium influx into retinal axons is regulated by presynaptic nicotinic acetylcholine receptor activity in vivo  Academic Article
  • Location of subunits within the acetylcholine-receptor by electron image-analysis of tubular crystals from torpedo-marmorata  Academic Article
  • Mice lacking the beta4 subunit of the nicotinic acetylcholine receptor show memory deficits, altered anxiety- and depression-like behavior, and diminished nicotine-induced analgesia  Academic Article
  • Molecular mechanisms underlying behaviors related to nicotine addiction  Academic Article
  • Monoclonal and anti-idiotypic antibodies as probes for receptor structure and function  Academic Article
  • Natural variation within the neuronal nicotinic acetylcholine receptor cluster on human chromosome 15q24: Influence on heritable autonomic traits in twin pairs  Academic Article
  • Neural nicotinic acetylcholine responses in sensory neurons from postnatal rat  Academic Article
  • Nicotinic acetylcholine receptor at 4.6 Å resolution: Transverse tunnels in the channel wall  Academic Article
  • Nicotinic acetylcholine receptor mRNA in dorsal root ganglion neurons  Academic Article
  • Nicotinic acetylcholine receptor subtypes expression during rat retina development and their regulation by visual experience  Academic Article
  • Nicotinic acetylcholine-receptor at 9 Å resolution  Academic Article
  • Nicotinic antagonists enhance process outgrowth by rat retinal ganglion cells in culture  Academic Article
  • Nicotinic receptor binding site probed with unnatural amino acid incorporation in intact cells  Academic Article
  • Nmr solution structure of alpha-conotoxin imi and comparison to other conotoxins specific for neuronal nicotinic acetylcholine receptors  Academic Article
  • On the origin of ion selectivity in the Cys-loop receptor family  Academic Article
  • Processing of chromogranin A by plasmin provides a novel mechanism for regulating catecholamine secretion  Academic Article
  • Projection structure of the nicotinic acetylcholine receptor: Distinct conformations of the alpha subunits  Academic Article
  • Prostate stem cell antigen is an endogenous lynx1-like prototoxin that antagonizes alpha7-containing nicotinic receptors and prevents programmed cell death of parasympathetic neurons  Academic Article
  • Recent advances in understanding nicotinic receptor signaling mechanisms that regulate drug self-administration behavior  Academic Article
  • Rediocides A and G as potential antitoxins against cobra venom  Academic Article
  • Refined structure of the nicotinic acetylcholine receptor at 4 Å resolution  Academic Article
  • Regulation of acetylcholine receptors on chick ciliary ganglion neurons by components from the synaptic target tissue  Academic Article
  • Reversible photocontrol of biological systems by the incorporation of molecular photoswitches  Academic Article
  • Reward and somatic changes during precipitated nicotine withdrawal in rats: Centrally and peripherally mediated effects  Academic Article
  • Role of complement in pathogenesis of experimental autoimmune myasthenia gravis  Academic Article
  • Selectivity optimization of substituted 1,2,3-triazoles as α7 nicotinic acetylcholine receptor agonists  Academic Article
  • Spontaneous release of acetylcholine affects the physiological nicotinic responses of rat retinal ganglion cells in culture  Academic Article
  • Stimulation of nicotinic receptors in the lateral septal nucleus increases anxiety  Academic Article
  • Structural and ligand recognition characteristics of an acetylcholine-binding protein from Aplysia californica  Academic Article
  • Structural basis for α-conotoxin potency and selectivity  Academic Article
  • Structural characterization of agonist and antagonist-bound acetylcholine-binding protein from Aplysia californica  Academic Article
  • Structural dynamics of the alpha-neurotoxin-acetylcholine-binding protein complex: Hydrodynamic and fluorescence anisotropy decay analyses  Academic Article
  • Structure and action of the nicotinic acetylcholine receptor explored by electron microscopy  Academic Article
  • Structure-activity relationships in a peptidic alpha 7 nicotinic acetylcholine receptor antagonist  Academic Article
  • Structure-guided drug design: Conferring selectivity among neuronal nicotinic receptor and acetylcholine-binding protein subtypes  Academic Article
  • Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations  Academic Article
  • Subtypes of nicotinic acetylcholine receptors in nicotine reward, dependence, and withdrawal: Evidence from genetically modified mice  Academic Article
  • Synthesis and activity of substituted heteroaromatics as positive allosteric modulators for α4β2α5 nicotinic acetylcholine receptors  Academic Article
  • Synthesis of selective agonists for the alpha 7 nicotinic acetylcholine receptor with in situ click-chemistry on acetylcholine-binding protein templates  Academic Article
  • Targeted deletion of the mouse α2 nicotinic acetylcholine receptor subunit gene (Chrna2) potentiates nicotine-modulated behaviors  Academic Article
  • The cholinergic system is involved in regulation of the development of the hematopoietic system  Academic Article
  • The croonian lecture 2000. Nicotinic acetylcholine receptor and the structural basis of fast synaptic transmission  Academic Article
  • The effect of crebanine on memory and cognition impairment via the alpha-7 nicotinic acetylcholine receptor  Academic Article
  • The nicotinic acetylcholine receptor of the torpedo electric ray  Academic Article
  • The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors  Academic Article
  • The novel α7 nicotinic acetylcholine receptor agonist N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-[2-(methoxy)phenyl]-1-benzofuran- 2-carboxamide improves working and recognition memory in rodents  Academic Article
  • Three-dimensional location of the main immunogenic region of the acetylcholine receptor  Academic Article
  • Tryptophan fluorescence reveals conformational changes in the acetylcholine binding protein  Academic Article
  • Varenicline blocks nicotine intake in rats with extended access to nicotine self-administration  Academic Article
  • Virtual screening against acetylcholine binding protein  Academic Article
  • Virtual screening against alpha-cobratoxin  Academic Article
  • Visualization of cholinoceptive neurons in the rat neocortex - colocalization of muscarinic and nicotinic acetylcholine-receptors  Academic Article

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