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Radiation Tolerance

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  • ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response  Academic Article
  • Androgen receptor upregulation mediates radioresistance after ionizing radiation  Academic Article
  • Cancer-predisposing mutations within the RING domain of BRCA1: Loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity  Academic Article
  • Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1  Academic Article
  • Dual functions of autophagy in the response of breast tumor cells to radiation: Cytoprotective autophagy with radiation alone and cytotoxic autophagy in radiosensitization by vitamin D-3  Academic Article
  • Glioblastoma therapy can be augmented by targeting IDH1-mediated NADPH biosynthesis  Academic Article
  • HSP90 inhibition as a means of radiosensitizing resistant, aggressive soft tissue sarcomas  Academic Article
  • Ku86 defines the genetic defect and restores X-ray resistance and V(D)J recombination to complementation group 5 hamster cell mutants  Academic Article
  • Pharmacological targeting of the thrombomodulin-activated protein c pathway mitigates radiation toxicity  Academic Article
  • Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA  Academic Article
  • Targeted disruption of the Artemis murine counterpart results in SCID and defective V(D)J recombination that is partially corrected with bone marrow transplantation  Academic Article
  • Targeting AKT with the proapoptotic peptide, TAT-CTMP: A novel strategy for the treatment of human pancreatic adenocarcinoma  Academic Article
  • The enzymology of nitric oxide in bacterial pathogenesis and resistance  Academic Article
  • The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response  Academic Article
  • The rad50 zinc-hook is a structure joining mre11 complexes in DNA recombination and repair  Academic Article
  • The radiomimetic enediyne, 20'-deschloro-C-1027 induces inter-strand DNA crosslinks in hypoxic cells and overcomes cytotoxic radioresistance  Academic Article

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