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Pyrimidinones

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  • ADME pharmacogenetics: investigation of the pharmacokinetics of the antiretroviral agent lopinavir coformulated with ritonavir  Academic Article
  • Alteration of red cell membrane organization in sickle cell anaemia  Academic Article
  • Atm regulates mre11-dependent DNA end-degradation and microhomology-mediated end joining  Academic Article
  • Cancer-derived mutations in the regulatory subunit p85α of phosphoinositide 3-kinase function through the catalytic subunit p110α  Academic Article
  • Crystallization and preliminary X-ray characterization of the nitrile reductase QueF: a queuosine-biosynthesis enzyme  Academic Article
  • Development of Pyrazolone and Isoxazol-5-one Cambinol Analogues as Sirtuin Inhibitors  Academic Article
  • Discovery of a potent, nonpolyglutamatable inhibitor of glycinamide ribonucleotide transformylase  Academic Article
  • FRAX597, a small molecule inhibitor of the p21-activated kinases, inhibits tumorigenesis of neurofibromatosis type 2 (NF2)-associated Schwannomas  Academic Article
  • Generation of infectious feline immunodeficiency virus (FIV) encoding FIV/human immunodeficiency virus chimeric protease  Academic Article
  • High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol  Academic Article
  • Identification and mechanism of action of a novel small-molecule inhibitor of arenavirus multiplication  Academic Article
  • Identification of novel therapeutic targets in acute leukemias with NRAS mutations using a pharmacologic approach  Academic Article
  • Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models  Academic Article
  • N1-Alkyl pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase  Academic Article
  • N1-Heterocyclic pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase  Academic Article
  • Orosomucoid (α1-acid glycoprotein) plasma concentration and genetic variants: Effects on human immunodeficiency virus protease inhibitor clearance and cellular accumulation  Academic Article
  • Phospholipid asymmetry in human erythrocyte ghosts  Academic Article
  • Pyrimidone-based series of glucokinase activators with alternative donor-acceptor motif  Academic Article
  • Role of the carbonyl group of the (6-4) photoproduct in the (6-4) photolyase reaction  Academic Article
  • Solid-phase synthesis of 3,4-dihydro-1H-pyrimidine-2-ones using sodium benzenesulfinate as a traceless linker  Academic Article
  • Solid-phase synthesis of 3,4-dihydro-1H-pyrimidine-2-ones using sodium benzenesulfinate as a traceless linker  Academic Article
  • TRPM8 is required for cold sensation in mice  Academic Article
  • The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 attenuates a scopolamine-induced deficit in a novel rodent attention task  Academic Article
  • Titanium(IV) isopropoxide mediated synthesis of pyrimidin-4-ones  Academic Article

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