subject area of
- ADME pharmacogenetics: investigation of the pharmacokinetics of the antiretroviral agent lopinavir coformulated with ritonavir Academic Article
- Alteration of red cell membrane organization in sickle cell anaemia Academic Article
- Atm regulates mre11-dependent DNA end-degradation and microhomology-mediated end joining Academic Article
- Cancer-derived mutations in the regulatory subunit p85α of phosphoinositide 3-kinase function through the catalytic subunit p110α Academic Article
- Crystallization and preliminary X-ray characterization of the nitrile reductase QueF: a queuosine-biosynthesis enzyme Academic Article
- Development of Pyrazolone and Isoxazol-5-one Cambinol Analogues as Sirtuin Inhibitors Academic Article
- Discovery of a potent, nonpolyglutamatable inhibitor of glycinamide ribonucleotide transformylase Academic Article
- FRAX597, a small molecule inhibitor of the p21-activated kinases, inhibits tumorigenesis of neurofibromatosis type 2 (NF2)-associated Schwannomas Academic Article
- Generation of infectious feline immunodeficiency virus (FIV) encoding FIV/human immunodeficiency virus chimeric protease Academic Article
- High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol Academic Article
- Identification and mechanism of action of a novel small-molecule inhibitor of arenavirus multiplication Academic Article
- Identification of novel therapeutic targets in acute leukemias with NRAS mutations using a pharmacologic approach Academic Article
- Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models Academic Article
- N1-Alkyl pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase Academic Article
- N1-Heterocyclic pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase Academic Article
- Orosomucoid (α1-acid glycoprotein) plasma concentration and genetic variants: Effects on human immunodeficiency virus protease inhibitor clearance and cellular accumulation Academic Article
- Phospholipid asymmetry in human erythrocyte ghosts Academic Article
- Pyrimidone-based series of glucokinase activators with alternative donor-acceptor motif Academic Article
- Role of the carbonyl group of the (6-4) photoproduct in the (6-4) photolyase reaction Academic Article
- Solid-phase synthesis of 3,4-dihydro-1H-pyrimidine-2-ones using sodium benzenesulfinate as a traceless linker Academic Article
- Solid-phase synthesis of 3,4-dihydro-1H-pyrimidine-2-ones using sodium benzenesulfinate as a traceless linker Academic Article
- TRPM8 is required for cold sensation in mice Academic Article
- The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 attenuates a scopolamine-induced deficit in a novel rodent attention task Academic Article
- Titanium(IV) isopropoxide mediated synthesis of pyrimidin-4-ones Academic Article