subject area of
- A new class of highly cytotoxic diketopiperazines Academic Article
- A unique class of duocarmycin and CC-1065 analogues subject to reductive activation Academic Article
- Assessment of solution-phase positional scanning libraries based on distamycin A for the discovery of new DNA binding agents Academic Article
- Bifunctional alkylating agents derived from duocarmycin SA: Potent antitumor activity with altered sequence selectivity Academic Article
- CC-1065/duocarmycin and bleomycin A(2) hybrid agents: lack of enhancement of DNA alkylation by attachment to noncomplementary DNA binding subunits Academic Article
- Design, synthesis and evaluation of bouvardin, deoxybouvardin and RA-I-XIV pharmacophore analogs Academic Article
- Design, synthesis, and evaluation of duocarmycin O-amino phenol prodrugs subject to tunable reductive activation Academic Article
- Efficacious cyclic N-acyl O-amino phenol duocarmycin prodrugs Academic Article
- Establishing the parabolic relationship between reactivity and activity for derivatives and analogues of the duocarmycin and CC-1065 alkylation subunits Academic Article
- Expression of h-2 antigens during growth of cultured tumor cells Academic Article
- Metal cation complexation and activation of reversed CPyi analogues of CC-1065 and duocarmycin SA: Partitioning the effects of binding and catalysis Academic Article
- Resolution of a CPzl precursor, synthesis and biological evaluation of (+) and (-)-NBoc-CPzl: a further validation of the relationship between chemical solvolytic stability and cytotoxicity Academic Article
- Streptonigrin and lavendamycin partial structures - probes for the minimum, potent pharmacophore of streptonigrin, lavendamycin, and synthetic quinoline-5,8-diones Academic Article
- Synthesis and antitumor activities of unsymmetrically substituted 1,4-bis (aminoalkyl)amino anthracene-9,10-diones and related systems Academic Article
- Synthesis and evaluation of a series of C3-substituted CBI analogues of CC-1065 and the duocarmycins Academic Article
- Synthesis, chemical properties, and biological evaluation of CC-1065 and duocarmycin analogues incorporating the 5-methoxycarbonyl-1,2,9,9a-tetrahydrocyclopropa c benz e indol-4-one alkylation subunit Academic Article
- Total synthesis and evaluation of cytostatin, its C10-C11 diastereomers, and additional key analogues: Impact on PP2A inhibition Academic Article
- Total synthesis of ningalin D Academic Article