Scripps VIVO scripps research logo

  • Index
  • Log in
  • Home
  • People
  • Organizations
  • Research
  • Events
Search form

Leukemia L1210

Concept
uri icon
  • Overview
scroll to property group menus

Overview

subject area of

  • A new class of highly cytotoxic diketopiperazines  Academic Article
  • A unique class of duocarmycin and CC-1065 analogues subject to reductive activation  Academic Article
  • Assessment of solution-phase positional scanning libraries based on distamycin A for the discovery of new DNA binding agents  Academic Article
  • Bifunctional alkylating agents derived from duocarmycin SA: Potent antitumor activity with altered sequence selectivity  Academic Article
  • CC-1065/duocarmycin and bleomycin A(2) hybrid agents: lack of enhancement of DNA alkylation by attachment to noncomplementary DNA binding subunits  Academic Article
  • Design, synthesis and evaluation of bouvardin, deoxybouvardin and RA-I-XIV pharmacophore analogs  Academic Article
  • Design, synthesis, and evaluation of duocarmycin O-amino phenol prodrugs subject to tunable reductive activation  Academic Article
  • Efficacious cyclic N-acyl O-amino phenol duocarmycin prodrugs  Academic Article
  • Establishing the parabolic relationship between reactivity and activity for derivatives and analogues of the duocarmycin and CC-1065 alkylation subunits  Academic Article
  • Expression of h-2 antigens during growth of cultured tumor cells  Academic Article
  • Metal cation complexation and activation of reversed CPyi analogues of CC-1065 and duocarmycin SA: Partitioning the effects of binding and catalysis  Academic Article
  • Resolution of a CPzl precursor, synthesis and biological evaluation of (+) and (-)-NBoc-CPzl: a further validation of the relationship between chemical solvolytic stability and cytotoxicity  Academic Article
  • Streptonigrin and lavendamycin partial structures - probes for the minimum, potent pharmacophore of streptonigrin, lavendamycin, and synthetic quinoline-5,8-diones  Academic Article
  • Synthesis and antitumor activities of unsymmetrically substituted 1,4-bis (aminoalkyl)amino anthracene-9,10-diones and related systems  Academic Article
  • Synthesis and evaluation of a series of C3-substituted CBI analogues of CC-1065 and the duocarmycins  Academic Article
  • Synthesis, chemical properties, and biological evaluation of CC-1065 and duocarmycin analogues incorporating the 5-methoxycarbonyl-1,2,9,9a-tetrahydrocyclopropa c benz e indol-4-one alkylation subunit  Academic Article
  • Total synthesis and evaluation of cytostatin, its C10-C11 diastereomers, and additional key analogues: Impact on PP2A inhibition  Academic Article
  • Total synthesis of ningalin D  Academic Article

©2021 The Scripps Research Institute | Terms of Use | Powered by VIVO

  • About
  • Contact Us
  • Support