subject area of
- A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate Academic Article
- A cross-species analysis in pancreatic neuroendocrine tumors reveals molecular subtypes with distinctive clinical, metastatic, developmental, and metabolic characteristics Academic Article
- A highly diastereo- and enantioselective synthesis of multisubstituted cyclopentanes with four chiral carbons by the organocatalytic domino Michael-Henry reaction Academic Article
- A novel method for transfer of 2-dimensional crystals from the air-water-interface to specimen grids - em-sample preparation lipid-layer crystallization Academic Article
- Activation of remote meta-C-H bonds assisted by an end-on template Academic Article
- Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer Academic Article
- Amino acid biosynthesis in the halophilic archaeon haloarcula hispanica Academic Article
- Amino acid catalyzed direct asymmetric aldol reactions: A bioorganic approach to catalytic asymmetric carbon-carbon bond-forming reactions Academic Article
- Asymmetric electrophilic fluorocyclization with carbon nucleophiles Academic Article
- Asymmetric total syntheses of aspidodasycarpine, lonicerine, and the proposed structure of lanciferine Academic Article
- Better chemistry through radicals Academic Article
- Bystanding F(+) oxidants enable selective reductive elimination from high-valent metal centers in catalysis Academic Article
- C-H activation generates period-shortening molecules that target cryptochrome in the mammalian circadian clock Academic Article
- C-H functionalization logic enables synthesis of (+)-hongoquercin A and related compounds Academic Article
- C-S bond cleavage by a polyketide synthase domain Academic Article
- CO2 fixation kinetics of Halothiobacillus neapolitanus mutant carboxysomes lacking carbonic anhydrase suggest the shell acts as a diffusional barrier for CO2 Academic Article
- Carbon-deuterium bonds as non-perturbative infrared probes of protein dynamics, electrostatics, heterogeneity, and folding Academic Article
- Carbon-deuterium bonds as probes of protein thermal unfolding Academic Article
- Catalytic and structural effects of amino acid substitution at histidine 30 in human manganese superoxide dismutase: Insertion of valine Cγ into the substrate access channel Academic Article
- Catalytic asymmetric C-H insertions of rhodium(II) azavinyl carbenes Academic Article
- Chain-length-dependent vibrational resonances in alkanethiol self-assembled monolayers observed on plasmonic nanoparticle substrates Academic Article
- Characterization of alkaline transitions in ferricytochrome c using carbon-deuterium infrared probes Academic Article
- Chemical expansion of cofactor activity Academic Article
- Citrullination of proteins: A common post-translational modification pathway induced by different nanoparticles in vitro and in vivo Academic Article
- Cloning and in vivo and in vitro regulation of cyclic AMP-dependent carbon starvation genes from Escherichia coli Academic Article
- Comparison of the anti-amyloidogenic effect of O-mannosylation, O-galactosylation, and O-GalNAc glycosylation Academic Article
- Computational fragment-based binding site identification by ligand competitive saturation Academic Article
- Conformation-induced remote meta-C-H activation of amines Academic Article
- Constructing multiply substituted arenes using sequential palladium(II)-catalyzed C-H olefination Academic Article
- Crystalline polymorphism induced by charge regulation in ionic membranes Academic Article
- Deuterium isotope effects on the central carbon metabolism of escherichia coli cells grown on a d2o-containing minimal medium Academic Article
- Diastereoselective dieckmann condensation suitable for introduction of the duocarmycin A C6 center - development of a divergent strategy for the total synthesis of duocarmycins A and SA Academic Article
- Direct C-H arylation of electron-deficient heterocycles with arylboronic acids Academic Article
- Direct asymmetric organocatalytic michael reactions of alpha,alpha-disubstituted aldehydes with beta-nitrostyrenes for the synthesis of quaternary carbon-containing products Academic Article
- Direct observation of structural heterogeneity in a β-sheet Academic Article
- Direct repeat sequences are implicated in the regulation of 2 streptomyces chitinase promoters that are subject to carbon catabolite control Academic Article
- Direct synthesis of fluorinated heteroarylether bioisosteres Academic Article
- Dissection of central carbon metabolism of hemoglobin-expressing escherichia coli by c-13 nuclear magnetic resonance flux distribution analysis in microaerobic bioprocesses Academic Article
- Does contamination buildup limit throughput for automated cryoEM? Academic Article
- Dosage delivery of sensitive reagents enables glove-box-free synthesis Academic Article
- Efforts toward developing probes of protein dynamics: Vibrational dephasing and relaxation of carbon-deuterium stretching modes in deuterated leucine Academic Article
- Elemental isomerism: A boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands Academic Article
- Enantioselective C-H olefination of α-hydroxy and α-amino phenylacetic acids by kinetic resolution Academic Article
- Enantioselective synthesis of quaternary carbon stereogenic centers through copper-catalyzed conjugate additions of aryl- and alkylaluminum reagents to acyclic trisubstituted enones Academic Article
- Enzymes for chemical synthesis Academic Article
- Ether-directed ortho-c-h olefination with a palladium(ii)/monoprotected amino acid catalyst Academic Article
- Exceedingly fast copper(II)-promoted ortho C-H trifluoromethylation of arenes using TMSCF(3) Academic Article
- Expedient drug synthesis and diversification via ortho-C-H iodination using recyclable PdI2 as the precatalyst Academic Article
- Forming tertiary organolithiums and organocuprates from nitrile precursors and their bimolecular reactions with carbon electrophiles to form quaternary carbon stereocenters Academic Article
- Functionalized olefin cross-coupling to construct carbon-carbon bonds Academic Article
- Hydrocarbon oxidation vs C-C bond-forming approaches for efficient syntheses of oxygenated molecules Academic Article
- If C-H bonds could talk: Selective C-H bond oxidation Academic Article
- Improved production of the tallysomycin h-1 in streptoalloteichus hindustanus sb8005 strain by fermentation optimization Academic Article
- Improving physical properties via C-H oxidation: chemical and enzymatic approaches Academic Article
- Infrared line shape of an alpha-carbon deuterium-labeled amino acid Academic Article
- Initial evaluation of a direct detection device detector for single particle cryo-electron microscopy Academic Article
- Innate C-H trifluoromethylation of heterocycles Academic Article
- Interactions of CUB with carbon monoxide in cytochrome c oxidase: Origin of the anomalous correlation between the Fe-CO and C-O stretching frequencies Academic Article
- Intracellular carbon fluxes in riboflavin-producing bacillus subtilis during growth on two-carbon substrate mixtures Academic Article
- Investigations of black bronchoalveolar human lavage fluid Academic Article
- Key mechanistic features of enantioselective c-h bond activation reactions catalyzed by (chiral mono-n-protected amino acid)-pd(ii) complexes Academic Article
- Lactonization as a general route to β-C(sp 3)-H functionalization
- Ligand-accelerated C-H activation reactions: evidence for a switch of mechanism Academic Article
- Ligand-controlled C(sp(3))-H arylation and olefination in synthesis of unnatural chiral alpha-amino acids Academic Article
- Ligand-enabled cross-coupling of C(sp(3))-H bonds with arylboron reagents via Pd(II)/Pd(0) catalysis Academic Article
- Ligand-enabled cross-coupling of C(sp(3))-H bonds with arylsilanes Academic Article
- Ligand-enabled gamma-C-H olefination and carbonylation: construction of beta-quaternary carbon centers Academic Article
- Ligand-enabled meta-C-H activation using a transient mediator Academic Article
- Ligand-enabled reactivity and selectivity in a synthetically versatile aryl C-H olefination Academic Article
- Ligand-enabled triple C-H activation reactions: one-pot synthesis of diverse 4-aryl-2-quinolinones from propionamides Academic Article
- MUC1 and HIF-1alpha signaling crosstalk induces anabolic glucose metabolism to impart gemcitabine resistance to pancreatic cancer Academic Article
- Membraneless vanadium redox fuel cell using laminar flow Academic Article
- Metabolic flux ratio analysis of genetic and environmental modulations of escherichia coli central carbon metabolism Academic Article
- Metabolic sugar signal promotes Arabidopsis meristematic proliferation via G2 Academic Article
- Metathesis reactions in total synthesis Academic Article
- Mitochondrial one-carbon pathway supports cytosolic folate integrity in cancer cells Academic Article
- Modulating "jousting" C-F---H-C interactions with a bit of hydrogen bonding Academic Article
- Monoselective o-C-H functionalizations of mandelic acid and α-phenylglycine Academic Article
- Natural product synthesis at the interface of chemistry and biology Academic Article
- Orchestrated triple C-H activation reactions using two directing groups: rapid assembly of complex pyrazoles Academic Article
- Overcoming the limitations of directed C-H functionalizations of heterocycles Academic Article
- Palladium(0)/PAr3-catalyzed intermolecular amination of C(sp3)[BOND]H bonds: Synthesis of ß-amino acids Academic Article
- Palladium-catalysed biscyclisation of allenic bromoalkenes through a zipper-mode cascade Academic Article
- Palladium-catalyzed asymmetric iodination of unactivated C-H bonds under mild conditions Academic Article
- Palladium-catalyzed cross-coupling reactions in total synthesis Academic Article
- Palladium-catalyzed ortho-selective C-H deuteration of arenes: evidence for superior reactivity of weakly coordinated palladacycles Academic Article
- Palladium-catalyzed oxidative double C-H functionalization/carbonylation for the synthesis of xanthones Academic Article
- Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion Academic Article
- Pd(II)-catalyzed C-H functionalizations directed by distal weakly coordinating functional groups Academic Article
- Pd(II)-catalyzed carbonylation of C(sp3)-H bonds: a new entry to 1,4-dicarbonyl compounds Academic Article
- Pd(II)-catalyzed hydroxyl-directed C-H olefination enabled by monoprotected amino acid ligands Academic Article
- Pd(II)-catalyzed olefination of sp(3) C-H bonds Academic Article
- Pd(ii)-catalyzed enantioselective activation of c(sp(2))-h and c(sp(3))-h bonds using monoprotected amino acids as chiral ligands Academic Article
- Pd-catalyzed oxidative ortho-c-h borylation of arenes Academic Article
- Practical and innate carbon-hydrogen functionalization of heterocycles Academic Article
- Precision polyelectrolytes with phenylsulfonic acid branches at every five carbons Academic Article
- QQS orphan gene regulates carbon and nitrogen partitioning across species via NF-YC interactions Academic Article
- RNA-catalysed carbon-carbon bond formation Academic Article
- Radical-based regioselective C-H functionalization of electron-deficient heteroarenes: scope, tunability, and predictability Academic Article
- Radical-mediated enzymatic carbon chain fragmentation-recombination Academic Article
- Rapid fluorescent screening for bifunctional amine-acid catalysts: Efficient syntheses of quaternary carbon-containing aldols under organocatalysis Academic Article
- Rational design of lipid for membrane protein crystallization Academic Article
- Reconstruction of the yeast Snf1 kinase regulatory network reveals its role as a global energy regulator Academic Article
- Recyclable sulfonated amorphous carbon catalyzed Friedel-Crafts alkylation of indoles with α,β-unsaturated carbonyl compounds in water Academic Article
- Redox-coupled dynamics and folding in cytochrome c Academic Article
- Role of N-acyl amino acid ligands in Pd(II)-catalyzed remote C-H activation of tethered arenes Academic Article
- Scalable and sustainable electrochemical allylic C-H oxidation Academic Article
- Scope and mechanism of direct indole and pyrrole couplings adjacent to carbonyl compounds: Total synthesis of acremoauxin A and oxazinin 3 Academic Article
- Selective autophagy of BES1 mediated by DSK2 balances plant growth and survival Academic Article
- Selective oxidation at carbon adjacent to aromatic systems with IBX Academic Article
- Site-selective aliphatic C-H chlorination using N-chloroamides enables a synthesis of chlorolissoclimide Academic Article
- Sphingolipids as bioactive regulators of thrombin generation Academic Article
- Stereoinversion of tertiary alcohols to tertiary-alkyl isonitriles and amines Academic Article
- Strain release in C-H bond activation? Academic Article
- Structural origins of efficient proton abstraction from carbon by a catalytic antibody Academic Article
- Structure of avian aicar transformylase with a multisubstrate adduct inhibitor β-DADF identifies the folate binding site Academic Article
- Studies on the Himbert intramolecular arene/allene Diels-Alder cycloaddition. Mechanistic studies and expansion of scope to all-carbon tethers Academic Article
- Studies on the synthesis of apoptolidin A. 1. Synthesis of the C(1)-C(11) fragment Academic Article
- Synthesis of beta-hydroxyaldehydes with stereogenic quaternary carbon centers by direct organocatalytic asymmetric aldol reactions Academic Article
- Synthesis of indolines and tetrahydroisoquinolines from arylethylamines by Pd(II)-catalyzed C-H activation reactions Academic Article
- Testing if the interstitial atom, X, of the nitrogenase molybdenum-iron cofactor is N or C: ENDOR, ESEEM, and DFT studies of the S = 3/2 resting state in multiple environments Academic Article
- The 2D [31P] spin-echo-difference constant-time [13C, 1H]-HMQC experiment for simultaneous determination of (3)J(H3'P) and (3)J(C4'P) in 13C-labeled nucleic acids and their protein complexes Academic Article
- The glmS riboswitch integrates signals from activating and inhibitory metabolites in vivo Academic Article
- The solution electrochemistry of tetrahydrobiopterin revisited Academic Article
- Theoretical calculations of carbon-oxygen bond dissociation enthalpies of peroxyl radicals formed in the autoxidation of lipids Academic Article
- Total synthesis and biological evaluation of (+)- and (-)-bisanthraquinone antibiotic BE-43472B and related compounds Academic Article
- Total synthesis of dimeric pyrrole-imidazole alkaloids: Sceptrin, ageliferin, nagelamide e, oxysceptrin, nakamuric acid, and the axinellamine carbon skeleton Academic Article
- Total synthesis of eudesmane terpenes by site-selective C-H oxidations Academic Article
- Toward 'omic scale metabolite profiling: a dual separation-mass spectrometry approach for coverage of lipid and central carbon metabolism Academic Article
- Transcription antitermination by a phosphorylated response regulator and cobalamin-dependent termination at a b(12) riboswitch contribute to ethanolamine utilization in enterococcus faecalis Academic Article
- Unlocking nature's C-H bonds Academic Article
- Unusual carbon-carbon bond formations between allylboronates and acetals or ketals catalyzed by a peculiar indium(I) Lewis acid Academic Article
- Widespread, but non-identical, association of proteasomal 19 and 20S proteins with yeast chromatin Academic Article
- α-Arylation of saturated azacycles and N-methylamines via palladium(II)-catalyzed C(sp(3))-H coupling Academic Article