subject area of

• A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate  Academic Article
• A cross-species analysis in pancreatic neuroendocrine tumors reveals molecular subtypes with distinctive clinical, metastatic, developmental, and metabolic characteristics  Academic Article
• A highly diastereo- and enantioselective synthesis of multisubstituted cyclopentanes with four chiral carbons by the organocatalytic domino Michael-Henry reaction  Academic Article
• A novel method for transfer of 2-dimensional crystals from the air-water-interface to specimen grids - em-sample preparation lipid-layer crystallization  Academic Article
• Activation of remote meta-C-H bonds assisted by an end-on template  Academic Article
• Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer  Academic Article
• Amino acid biosynthesis in the halophilic archaeon haloarcula hispanica  Academic Article
• Amino acid catalyzed direct asymmetric aldol reactions: A bioorganic approach to catalytic asymmetric carbon-carbon bond-forming reactions  Academic Article
• Asymmetric electrophilic fluorocyclization with carbon nucleophiles  Academic Article
• Asymmetric total syntheses of aspidodasycarpine, lonicerine, and the proposed structure of lanciferine  Academic Article
• Better chemistry through radicals  Academic Article
• Bystanding F(+) oxidants enable selective reductive elimination from high-valent metal centers in catalysis  Academic Article
• C-H activation generates period-shortening molecules that target cryptochrome in the mammalian circadian clock  Academic Article
• C-H functionalization logic enables synthesis of (+)-hongoquercin A and related compounds  Academic Article
• C-S bond cleavage by a polyketide synthase domain  Academic Article
• CO2 fixation kinetics of Halothiobacillus neapolitanus mutant carboxysomes lacking carbonic anhydrase suggest the shell acts as a diffusional barrier for CO2  Academic Article
• Carbon-deuterium bonds as non-perturbative infrared probes of protein dynamics, electrostatics, heterogeneity, and folding  Academic Article
• Carbon-deuterium bonds as probes of protein thermal unfolding  Academic Article
• Catalytic and structural effects of amino acid substitution at histidine 30 in human manganese superoxide dismutase: Insertion of valine Cγ into the substrate access channel  Academic Article
• Catalytic asymmetric C-H insertions of rhodium(II) azavinyl carbenes  Academic Article
• Chain-length-dependent vibrational resonances in alkanethiol self-assembled monolayers observed on plasmonic nanoparticle substrates  Academic Article
• Characterization of alkaline transitions in ferricytochrome c using carbon-deuterium infrared probes  Academic Article
• Chemical expansion of cofactor activity  Academic Article
• Citrullination of proteins: A common post-translational modification pathway induced by different nanoparticles in vitro and in vivo  Academic Article
• Cloning and in vivo and in vitro regulation of cyclic AMP-dependent carbon starvation genes from Escherichia coli  Academic Article
• Comparison of the anti-amyloidogenic effect of O-mannosylation, O-galactosylation, and O-GalNAc glycosylation  Academic Article
• Computational fragment-based binding site identification by ligand competitive saturation  Academic Article
• Conformation-induced remote meta-C-H activation of amines  Academic Article
• Constructing multiply substituted arenes using sequential palladium(II)-catalyzed C-H olefination  Academic Article
• Crystalline polymorphism induced by charge regulation in ionic membranes  Academic Article
• Deuterium isotope effects on the central carbon metabolism of escherichia coli cells grown on a d2o-containing minimal medium  Academic Article
• Diastereoselective dieckmann condensation suitable for introduction of the duocarmycin A C6 center - development of a divergent strategy for the total synthesis of duocarmycins A and SA  Academic Article
• Direct C-H arylation of electron-deficient heterocycles with arylboronic acids  Academic Article
• Direct asymmetric organocatalytic michael reactions of alpha,alpha-disubstituted aldehydes with beta-nitrostyrenes for the synthesis of quaternary carbon-containing products  Academic Article
• Direct observation of structural heterogeneity in a β-sheet  Academic Article
• Direct repeat sequences are implicated in the regulation of 2 streptomyces chitinase promoters that are subject to carbon catabolite control  Academic Article
• Direct synthesis of fluorinated heteroarylether bioisosteres  Academic Article
• Dissection of central carbon metabolism of hemoglobin-expressing escherichia coli by c-13 nuclear magnetic resonance flux distribution analysis in microaerobic bioprocesses  Academic Article
• Does contamination buildup limit throughput for automated cryoEM?  Academic Article
• Dosage delivery of sensitive reagents enables glove-box-free synthesis  Academic Article
• Efforts toward developing probes of protein dynamics: Vibrational dephasing and relaxation of carbon-deuterium stretching modes in deuterated leucine  Academic Article
• Elemental isomerism: A boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands  Academic Article
• Enantioselective C-H olefination of α-hydroxy and α-amino phenylacetic acids by kinetic resolution  Academic Article
• Enantioselective synthesis of quaternary carbon stereogenic centers through copper-catalyzed conjugate additions of aryl- and alkylaluminum reagents to acyclic trisubstituted enones  Academic Article
• Enzymes for chemical synthesis  Academic Article
• Ether-directed ortho-c-h olefination with a palladium(ii)/monoprotected amino acid catalyst  Academic Article
• Exceedingly fast copper(II)-promoted ortho C-H trifluoromethylation of arenes using TMSCF(3)  Academic Article
• Expedient drug synthesis and diversification via ortho-C-H iodination using recyclable PdI2 as the precatalyst  Academic Article
• Forming tertiary organolithiums and organocuprates from nitrile precursors and their bimolecular reactions with carbon electrophiles to form quaternary carbon stereocenters  Academic Article
• Functionalized olefin cross-coupling to construct carbon-carbon bonds  Academic Article
• Hydrocarbon oxidation vs C-C bond-forming approaches for efficient syntheses of oxygenated molecules  Academic Article
• If C-H bonds could talk: Selective C-H bond oxidation  Academic Article
• Improved production of the tallysomycin h-1 in streptoalloteichus hindustanus sb8005 strain by fermentation optimization  Academic Article
• Improving physical properties via C-H oxidation: chemical and enzymatic approaches  Academic Article
• Infrared line shape of an alpha-carbon deuterium-labeled amino acid  Academic Article
• Initial evaluation of a direct detection device detector for single particle cryo-electron microscopy  Academic Article
• Innate C-H trifluoromethylation of heterocycles  Academic Article
• Interactions of CUB with carbon monoxide in cytochrome c oxidase: Origin of the anomalous correlation between the Fe-CO and C-O stretching frequencies  Academic Article
• Intracellular carbon fluxes in riboflavin-producing bacillus subtilis during growth on two-carbon substrate mixtures  Academic Article
• Investigations of black bronchoalveolar human lavage fluid  Academic Article
• Key mechanistic features of enantioselective c-h bond activation reactions catalyzed by (chiral mono-n-protected amino acid)-pd(ii) complexes  Academic Article
• Ligand-accelerated C-H activation reactions: evidence for a switch of mechanism  Academic Article
• Ligand-controlled C(sp(3))-H arylation and olefination in synthesis of unnatural chiral alpha-amino acids  Academic Article
• Ligand-enabled cross-coupling of C(sp(3))-H bonds with arylboron reagents via Pd(II)/Pd(0) catalysis  Academic Article
• Ligand-enabled cross-coupling of C(sp(3))-H bonds with arylsilanes  Academic Article
• Ligand-enabled gamma-C-H olefination and carbonylation: construction of beta-quaternary carbon centers  Academic Article
• Ligand-enabled meta-C-H activation using a transient mediator  Academic Article
• Ligand-enabled reactivity and selectivity in a synthetically versatile aryl C-H olefination  Academic Article
• Ligand-enabled triple C-H activation reactions: one-pot synthesis of diverse 4-aryl-2-quinolinones from propionamides  Academic Article
• MUC1 and HIF-1alpha signaling crosstalk induces anabolic glucose metabolism to impart gemcitabine resistance to pancreatic cancer  Academic Article
• Membraneless vanadium redox fuel cell using laminar flow  Academic Article
• Metabolic flux ratio analysis of genetic and environmental modulations of escherichia coli central carbon metabolism  Academic Article
• Metabolic sugar signal promotes Arabidopsis meristematic proliferation via G2  Academic Article
• Metathesis reactions in total synthesis  Academic Article
• Mitochondrial one-carbon pathway supports cytosolic folate integrity in cancer cells  Academic Article
• Modulating "jousting" C-F---H-C interactions with a bit of hydrogen bonding  Academic Article
• Monoselective o-C-H functionalizations of mandelic acid and α-phenylglycine  Academic Article
• Natural product synthesis at the interface of chemistry and biology  Academic Article
• Orchestrated triple C-H activation reactions using two directing groups: rapid assembly of complex pyrazoles  Academic Article
• Overcoming the limitations of directed C-H functionalizations of heterocycles  Academic Article
• Palladium(0)/PAr3-catalyzed intermolecular amination of C(sp3)[BOND]H bonds: Synthesis of ß-amino acids  Academic Article
• Palladium-catalysed biscyclisation of allenic bromoalkenes through a zipper-mode cascade  Academic Article
• Palladium-catalyzed asymmetric iodination of unactivated C-H bonds under mild conditions  Academic Article
• Palladium-catalyzed cross-coupling reactions in total synthesis  Academic Article
• Palladium-catalyzed ortho-selective C-H deuteration of arenes: evidence for superior reactivity of weakly coordinated palladacycles  Academic Article
• Palladium-catalyzed oxidative double C-H functionalization/carbonylation for the synthesis of xanthones  Academic Article
• Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion  Academic Article
• Pd(II)-catalyzed C-H functionalizations directed by distal weakly coordinating functional groups  Academic Article
• Pd(II)-catalyzed carbonylation of C(sp3)-H bonds: a new entry to 1,4-dicarbonyl compounds  Academic Article
• Pd(II)-catalyzed hydroxyl-directed C-H olefination enabled by monoprotected amino acid ligands  Academic Article
• Pd(II)-catalyzed olefination of sp(3) C-H bonds  Academic Article
• Pd(ii)-catalyzed enantioselective activation of c(sp(2))-h and c(sp(3))-h bonds using monoprotected amino acids as chiral ligands  Academic Article
• Pd-catalyzed oxidative ortho-c-h borylation of arenes  Academic Article
• Practical and innate carbon-hydrogen functionalization of heterocycles  Academic Article
• Precision polyelectrolytes with phenylsulfonic acid branches at every five carbons  Academic Article
• QQS orphan gene regulates carbon and nitrogen partitioning across species via NF-YC interactions  Academic Article
• RNA-catalysed carbon-carbon bond formation  Academic Article
• Radical-based regioselective C-H functionalization of electron-deficient heteroarenes: scope, tunability, and predictability  Academic Article
• Radical-mediated enzymatic carbon chain fragmentation-recombination  Academic Article
• Rapid fluorescent screening for bifunctional amine-acid catalysts: Efficient syntheses of quaternary carbon-containing aldols under organocatalysis  Academic Article
• Rational design of lipid for membrane protein crystallization  Academic Article
• Reconstruction of the yeast Snf1 kinase regulatory network reveals its role as a global energy regulator  Academic Article
• Recyclable sulfonated amorphous carbon catalyzed Friedel-Crafts alkylation of indoles with α,β-unsaturated carbonyl compounds in water  Academic Article
• Redox-coupled dynamics and folding in cytochrome c  Academic Article
• Role of N-acyl amino acid ligands in Pd(II)-catalyzed remote C-H activation of tethered arenes  Academic Article
• Scalable and sustainable electrochemical allylic C-H oxidation  Academic Article
• Scope and mechanism of direct indole and pyrrole couplings adjacent to carbonyl compounds: Total synthesis of acremoauxin A and oxazinin 3  Academic Article
• Selective autophagy of BES1 mediated by DSK2 balances plant growth and survival  Academic Article
• Selective oxidation at carbon adjacent to aromatic systems with IBX  Academic Article
• Site-selective aliphatic C-H chlorination using N-chloroamides enables a synthesis of chlorolissoclimide  Academic Article
• Sphingolipids as bioactive regulators of thrombin generation  Academic Article
• Stereoinversion of tertiary alcohols to tertiary-alkyl isonitriles and amines  Academic Article
• Strain release in C-H bond activation?  Academic Article
• Structural origins of efficient proton abstraction from carbon by a catalytic antibody  Academic Article
• Structure of avian aicar transformylase with a multisubstrate adduct inhibitor β-DADF identifies the folate binding site  Academic Article
• Studies on the Himbert intramolecular arene/allene Diels-Alder cycloaddition. Mechanistic studies and expansion of scope to all-carbon tethers  Academic Article
• Studies on the synthesis of apoptolidin A. 1. Synthesis of the C(1)-C(11) fragment  Academic Article
• Synthesis of beta-hydroxyaldehydes with stereogenic quaternary carbon centers by direct organocatalytic asymmetric aldol reactions  Academic Article
• Synthesis of indolines and tetrahydroisoquinolines from arylethylamines by Pd(II)-catalyzed C-H activation reactions  Academic Article
• Testing if the interstitial atom, X, of the nitrogenase molybdenum-iron cofactor is N or C: ENDOR, ESEEM, and DFT studies of the S = 3/2 resting state in multiple environments  Academic Article
• The 2D [31P] spin-echo-difference constant-time [13C, 1H]-HMQC experiment for simultaneous determination of (3)J(H3'P) and (3)J(C4'P) in 13C-labeled nucleic acids and their protein complexes  Academic Article
• The glmS riboswitch integrates signals from activating and inhibitory metabolites in vivo  Academic Article
• The solution electrochemistry of tetrahydrobiopterin revisited  Academic Article
• Theoretical calculations of carbon-oxygen bond dissociation enthalpies of peroxyl radicals formed in the autoxidation of lipids  Academic Article
• Total synthesis and biological evaluation of (+)- and (-)-bisanthraquinone antibiotic BE-43472B and related compounds  Academic Article
• Total synthesis of dimeric pyrrole-imidazole alkaloids: Sceptrin, ageliferin, nagelamide e, oxysceptrin, nakamuric acid, and the axinellamine carbon skeleton  Academic Article
• Total synthesis of eudesmane terpenes by site-selective C-H oxidations  Academic Article
• Toward 'omic scale metabolite profiling: a dual separation-mass spectrometry approach for coverage of lipid and central carbon metabolism  Academic Article
• Transcription antitermination by a phosphorylated response regulator and cobalamin-dependent termination at a b(12) riboswitch contribute to ethanolamine utilization in enterococcus faecalis  Academic Article
• Unlocking nature's C-H bonds  Academic Article
• Unusual carbon-carbon bond formations between allylboronates and acetals or ketals catalyzed by a peculiar indium(I) Lewis acid  Academic Article
• Widespread, but non-identical, association of proteasomal 19 and 20S proteins with yeast chromatin  Academic Article
• α-Arylation of saturated azacycles and N-methylamines via palladium(II)-catalyzed C(sp(3))-H coupling  Academic Article