subject area of
- A contemporary assessment of low-molecular-weight heparin for the treatment of acute coronary syndromes: Factoring in new trials and meta-analysis data Academic Article
- Abciximab therapy and unplanned coronary stent deployment - favorable effects on stent use, clinical outcomes, and bleeding complications Academic Article
- Activated protein C Academic Article
- Activated protein C mutant with minimal anticoagulant activity, normal cytoprotective activity, and preservation of thrombin activable fibrinolysis inhibitor-dependent cytoprotective functions Academic Article
- Activated protein C reduces graft neutrophil activation in clinical renal transplantation Academic Article
- Activated protein C resistance: What have we learned now that the dust has settled? Academic Article
- Activated protein C targets CD8(+) dendritic cells to reduce the mortality of endotoxemia in mice Academic Article
- Activated protein C variants with normal cytoprotective but reduced anticoagulant activity Academic Article
- Activated protein C-dependent and -independent anticoagulant activities of protein S have different structural requirements Academic Article
- Activated protein C: biased for translation Academic Article
- Activation of protein C and hemodynamic recovery after coronary artery bypass surgery Academic Article
- Acylcarnitines are anticoagulants that inhibit factor Xa and are reduced in venous thrombosis, based on metabolomics data Academic Article
- Adjunctive therapy for percutaneous revascularization in acute myocardial infarction Academic Article
- American College of Medical Genetics consensus statement on factor V Leiden mutation testing Academic Article
- An activated protein c analog with reduced anticoagulant activity extends the therapeutic window of tissue plasminogen activator for ischemic stroke in rodents Academic Article
- An antitissue factor monoclonal-antibody which inhibits tf-viia complex is a potent anticoagulant in plasma Academic Article
- An engineered Factor Va prevents bleeding induced by anticoagulant wt activated protein C Academic Article
- Anticoagulant dysfunction of human Arg352Trp-activated protein C caused by defective factor Va inactivation Academic Article
- Anticoagulant responses to thrombin are enhanced during regression of atherosclerosis in monkeys Academic Article
- Anticoagulant synergism of heparin and activated protein C in vitro - role of a novel anticoagulant mechanism of heparin, enhancement of inactivation of factor V by activated protein C Academic Article
- Antiplatelet and anticoagulant therapy in the secondary prevention of ischemic heart disease Academic Article
- Antiplatelet and anticoagulant use after myocardial infarction Academic Article
- Antithrombotic activity of protein S infused without activated protein C in a baboon thrombosis model Academic Article
- Antithrombotic therapy with intracoronary stenting Academic Article
- Aspirin dose and six-month outcome after an acute coronary syndrome Academic Article
- Attenuation of rebound ischemia after discontinuation of heparin therapy by glycoprotein iib/iiia inhibition with eptifibatide in patients with acute coronary syndromes - observations from the platelet iib/iiia in unstable angina: Receptor suppression using integrilin therapy (pursuit) trial Academic Article
- Binding site for blood coagulation factor Xa involving residues 311-325 in factor Va Academic Article
- Binding sites for blood coagulation factor Xa and protein S involving residues 493-506 in factor Va Academic Article
- Bivalirudin and provisional glycoprotein iib/iiia blockade compared with heparin and planned glycoprotein iib/iiia blockade during percutaneous coronary intervention - replace-2 randomized trial Academic Article
- Bivalirudin versus heparin and glycoprotein iib/iiia inhibition among patients with renal impairment undergoing percutaneous coronary intervention (a subanalysis of the replace-2 trial) Academic Article
- Bivalirudin vs heparin in percutaneous coronary intervention: A pooled analysis Academic Article
- Bivalirudin with planned or provisional abciximab versus low-dose heparin and abciximab during percutaneous coronary revascularization: Results of the comparison of abciximab complications with hirulog for ischemic events trial (cachet) Academic Article
- Changing roles of anticoagulant and antiplatelet treatment during percutaneous coronary intervention Academic Article
- Characterization of myocardial infarction as an end point in two large trials of acute coronary syndromes Academic Article
- Chemical synthesis and spontaneous folding of a multidomain protein: anticoagulant microprotein S Academic Article
- Cholesterol enhances phospholipid-dependent activated protein c anticoagulant activity Academic Article
- Clinical outcomes of bivalirudin for ischemic heart disease Academic Article
- Clinical-studies of protein-C Academic Article
- Comparison of bivalirudin versus heparin during percutaneous coronary intervention (the randomized evaluation of pci linking angiomax to reduced clinical events replace -1 trial) Academic Article
- Contemporary clinical-trials of restenosis Academic Article
- Continuing education course #2: Current understanding of hemostasis Academic Article
- Creatine kinase-mb elevation after coronary artery bypass grafting surgery in patients with non-st-segment elevation acute coronary syndromes predict worse outcomes: Results from four large clinical trials Academic Article
- Current role of platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes Academic Article
- Cytoprotective activated protein C averts Nlrp3 inflammasome-induced ischemia-reperfusion injury via mTORC1 inhibition Academic Article
- Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes Academic Article
- Dermatan sulfate and LMW heparin enhance the anticoagulant action of activated protein C Academic Article
- Design, synthesis, and biological evaluation of peptidomimetic inhibitors of factor XIa as novel anticoagulants Academic Article
- Design, synthesis, and biological evaluation of pyrazinones containing novel P1 needles as inhibitors of TF/VIIa Academic Article
- Direct anticoagulant activity of protein S-C4b binding protein complex in heerlen heterozygotes and normals Academic Article
- Direct thrombin inhibition appears to be a safe and effective anticoagulant for percutaneous bypass graft interventions Academic Article
- Direct thrombin inhibitors in acute coronary syndromes: Effect in patients undergoing early percutaneous coronary intervention Academic Article
- Dissociation of lpl and ldl: Effects of lipoproteins and anti-apob antibodies Academic Article
- Economic assessment of platelet glycoprotein iib/iiia inhibition for prevention of ischemic complications of high-risk coronary angioplasty Academic Article
- Economic evaluation of bivalirudin with provisional glycoprotein iib/iiia inhibition versus heparin with routine glycoprotein iib/iiia inhibition for percutaneous coronary intervention - results from the replace-2 trial Academic Article
- Effect of a home-based wearable continuous ECG monitoring patch on detection of undiagnosed atrial fibrillation the mSToPS randomized clinical trial Academic Article
- Effectiveness of early coronary angioplasty and abciximab for failed thrombolysis (reteplase or alteplase) during acute myocardial infarction (results from the gusto-iii trial) Academic Article
- Effects of integrelin, a platelet glycoprotein iib/iiia receptor antagonist, in unstable angina - a randomized multicenter trial Academic Article
- Efficacy of anti-coagulant treatment with argatroban on cardioembolic stroke Academic Article
- Engineered recombinant factor vii q(217) variants with altered inhibitor specificities Academic Article
- Engineered virus-like nanoparticles reverse heparin anticoagulation more consistently than protamine in plasma from heparin-treated patients Academic Article
- Enoxaparin in primary and facilitated percutaneous coronary intervention a formal prospective nonrandomized substudy of the finesse trial (facilitated intervention with enhanced reperfusion speed to stop events) Academic Article
- Evaluation and management of thrombocytopenia and suspected heparin-induced thrombocytopenia in hospitalized patients: The Complications After Thrombocytopenia Caused by Heparin (CATCH) registry Academic Article
- Evolution of improved antithrombotic and antiplatelet agents: Genesis of the comparison of abciximab complications with hirulog and back-up abciximab events trial (cachet) Academic Article
- Facilitation of early percutaneous coronary intervention after reteplase with or without abciximab in acute myocardial infarction - results from the speed (gusto-4 pilot) trial Academic Article
- First-in-human experience of an antidote-controlled anticoagulant using RNA aptamer technology - A phase 1a pharmacodynamic evaluation of a drug-antidote pair for the controlled regulation of factor IXa activity Academic Article
- Glucosylceramide, a neutral glycosphingolipid anticoagulant cofactor, enhances the interaction of human- and bovine-activated protein C with negatively charged phospholipid vesicles Academic Article
- Heparin and alkalinized lidocaine versus alkalinized lidocaine for treatment of interstitial cystitis symptoms Academic Article
- Heparin as an adjuvant to thrombolytic therapy in acute myocardial infarction Academic Article
- Heparin-induced thrombocytopenia Academic Article
- Heparin-induced thrombocytopenia and cardiovascular diseases Academic Article
- High-density lipoprotein enhancement of anticoagulant activities of plasma protein S and activated protein C Academic Article
- Impact of anticoagulation regimens on sheath management and bleeding in patients undergoing elective percutaneous coronary intervention in the STEEPLE trial Academic Article
- Impact of chronic antiplatelet therapy before hospitalization on ischemic and bleeding events in invasively managed patients with acute coronary syndromes: the ACUITY trial Academic Article
- Impaired anticoagulant response to infusion of thrombin in atherosclerotic monkeys associated with acquired defects in the protein c system Academic Article
- Incidence and prevention of ischemic stroke following myocardial infarction: review of current literature Academic Article
- Influence of blockade at specific levels of the coagulation cascade on restenosis in a rabbit atherosclerotic femoral-artery injury model Academic Article
- Influence of the 3K3A-activated protein C variant on the plasma clot lysis activity of t-PA and of t-PA on the variant's anticoagulant activity Academic Article
- Influence of timing of clopidogrel treatment on the efficacy and safety of bivalirudin in patients with non-ST-segment elevation acute coronary syndromes undergoing percutaneous coronary intervention: an analysis of the ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) trial Academic Article
- Inherent flexibility in a potent inhibitor of blood coagulation, recombinant nematode anticoagulant protein c2 Academic Article
- Inhibition of staurosporine-induced apoptosis of endothelial cells by activated protein C requires protease-activated receptor-1 and endothelial cell protein C receptor Academic Article
- Interactions and inhibition of blood-coagulation factor-Va involving residues 311-325 of activated protein-C Academic Article
- Interdomain engineered disulfide bond permitting elucidation of mechanisms of inactivation of coagulation factor Va by activated protein C Academic Article
- International, randomized, controlled trial of lamifiban (a platelet glycoprotein iib/iiia inhibitor), heparin, or both in unstable angina Academic Article
- Intravenous low-molecular-weight heparins compared with unfractionated heparin in percutaneous coronary intervention: quantitative review of randomized trials Academic Article
- Ischemic and bleeding outcomes in women treated with bivalirudin during percutaneous coronary intervention: a subgroup analysis of the Randomized Evaluation in PCI Linking Angiomax to Reduced Clinical Events (REPLACE)-2 trial Academic Article
- JLK isocoumarin inhibitors: Selective gamma-secretase inhibitors that do not interfere with notch pathway in vitro or in vivo Academic Article
- Lack of clopidogrel pretreatment effect on the relative efficacy of bivalirudin with provisional glycoprotein iib/iiia blockade compared to heparin with routine glycoprotein iib/iiia blockade - a replace-2 substudy Academic Article
- Limited generation of activated protein C during infusion of the protein C activator thrombin analog W215A/E217A in primates Academic Article
- Local drug delivery systems and prevention of restenosis Academic Article
- Long-term efficacy of bivalirudin and provisional glycoprotein iib/iiia blockade vs heparin and planned glycoprotein iib/iiia blockade during percutaneous coronary revascularization - replace-2 randomized trial Academic Article
- Long-term mortality of patients with acute myocardial infarction in the united states and canada - comparison of patients enrolled in global utilization of streptokinase and t-pa for occluded coronary arteries (gusto)-i Academic Article
- Mechanisms of anticoagulant and cytoprotective actions of the protein C pathway Academic Article
- N-CAM binding inhibits the proliferation of hippocampal progenitor cells and promotes their differentiation to a neuronal phenotype Academic Article
- N-terminal pro-brain natriuretic peptide and other risk markers for the separate prediction of mortality and subsequent myocardial infarction in patients with unstable coronary artery disease - a global utilization of strategies to open occluded arteries (gusto)-iv substudy Academic Article
- Neuroprotective activities of activated protein C mutant with reduced anticoagulant activity Academic Article
- Neurotoxicity of the anticoagulant-selective E149A-activated protein C variant after focal ischemic stroke in mice Academic Article
- Neutral glycosphingolipid-dependent inactivation of coagulation factor Va by activated protein C and protein S Academic Article
- Neutrophils release brakes of coagulation Academic Article
- Nonenzymatic anticoagulant activity of the mutant serine protease Ser360Ala-activated protein C mediated by factor Va Academic Article
- Oral anticoagulation reduces activated protein C less than protein C and other vitamin K-dependent clotting factors Academic Article
- Outcomes of patients with acute coronary syndromes who are treated with bivalirudin during percutaneous coronary intervention: An analysis from the randomized evaluation in pci linking angiomax to reduced clinical events (replace-2) trial Academic Article
- Patient stratification and its predictive value for cardiac events Academic Article
- Pharmacological approaches for the prevention of restenosis after percutaneous coronary intervention Academic Article
- Phase 1 safety, tolerability and pharmacokinetics of 3K3A-APC in healthy adult volunteers Academic Article
- Planned versus provisional use of glycoprotein iib/iiia inhibitors in smokers undergoing percutaneous' coronary intervention Academic Article
- Plasma contains protein S monomers and multimers with similar direct anticoagulant activity Academic Article
- Plasma protein S contains zinc essential for efficient activated protein C-independent anticoagulant activity and binding to factor Xa, but not for efficient binding to tissue factor pathway inhibitor Academic Article
- Plasma protein S residues 37-50 mediate its binding to factor Va and inhibition of blood coagulation Academic Article
- Platelet glycoprotein IIb/IIIa inhibition in acute coronary syndromes - gradient of benefit related to the revascularization strategy Academic Article
- Platelet glycoprotein IIb/IIIa receptor blockade and low-dose heparin during percutaneous coronary revascularization Academic Article
- Platelet glycoprotein IIb/IIIa receptor blockade in coronary artery disease Academic Article
- Platelet glycoprotein iib/iia receptor blockade with abciximab reduces ischemic complications in patients undergoing directional coronary atherectomy Academic Article
- Practice patterns and outcomes of percutaneous coronary interventions in the united states: 1995 to 1997 Academic Article
- Preclinical safety and pharmacokinetic profile of 3K3A-APC, a novel, modified activated protein C for ischemic stroke Academic Article
- Prediction of 30-day mortality among patients with thrombolysis-related intracranial hemorrhage Academic Article
- Primary percutaneous coronary intervention vs. Fibrinolytic therapy for acute st-elevation myocardial infarction in the elderly Academic Article
- Promise of combined low-molecular-weight heparin and platelet glycoprotein iib/iiia inhibition: Results from platelet iib/iiia antagonist for the reduction of acute coronary syndrome events in a global organization network b (paragon b) Academic Article
- Protein C anticoagulant activity in relation to anti-inflammatory and anti-apoptotic activities Academic Article
- Protein S confers neuronal protection during ischemic/hypoxic injury in mice Academic Article
- Protein S is inducible by interleukin 4 in T cells and inhibits lymphoid cell procoagulant activity Academic Article
- Protein S multimers and monomers each have direct anticoagulant activity Academic Article
- Protein c anticoagulant and cytoprotective pathways Academic Article
- Real-time analysis of shear-dependent thrombus formation and its blockade by inhibitors of von Willebrand factor binding to platelets Academic Article
- Recent advances in anticoagulant therapy for acute coronary syndromes Academic Article
- Recombinant murine-activated protein C is neuroprotective in a murine ischemic stroke model Academic Article
- Reduction in vascular access site bleeding in sequential abciximab coronary intervention trials Academic Article
- Reevaluation of total, free, and bound protein-S and C4b-binding protein-levels in plasma anticoagulated with citrate or hirudin Academic Article
- Relationship between activated clotting time and ischemic or hemorrhagic complications - analysis of 4 recent randomized clinical trials of percutaneous coronary intervention Academic Article
- Relationship between delay in performing direct coronary angioplasty and early clinical outcome in patients with acute myocardial infarction - results from the global use of strategies to open occluded arteries in acute coronary syndromes (gusto-iib) trial Academic Article
- Relative antithrombotic and andhernostatic effects of protein C activator versus low-molecular-weight heparin in primates Academic Article
- Resistance to activated protein C: A common inherited cause of venous thrombosis Academic Article
- Revisiting optimal anticoagulation with unfractionated heparin during coronary stent implantation Academic Article
- Risk of stroke associated with abciximab among patients undergoing percutaneous coronary intervention Academic Article
- Role of the PROS1 gene in thrombosis: lessons and controversies Academic Article
- Role of zymogen and activated factor x as scaffolds for the inhibition of the blood coagulation factor viia-tissue factor complex by recombinant nematode anticoagulant protein c2 Academic Article
- Safe and efficacious use of bivalirudin for percutaneous coronary intervention with adjunctive platelet glycoprotein IIb/IIIa receptor inhibition Academic Article
- Safety of abciximab during percutaneous coronary intervention in patients with chronic renal insufficiency Academic Article
- Science review: Role of coagulation protease cascades in sepsis Academic Article
- Selection of thrombolytic therapy for individual patients: Development of a clinical model Academic Article
- Soluble thrombomodulin is antithrombotic in the presence of neutralising antibodies to protein C and reduces circulating activated protein C levels in primates Academic Article
- Species-dependent neuroprotection by activated protein C mutants with reduced anticoagulant activity Academic Article
- Species-specific anticoagulant and mitogenic activities of murine protein S Academic Article
- Specificity of coagulation factor signaling Academic Article
- Sphingolipids as bioactive regulators of thrombin generation Academic Article
- Stenting for ischemic heart disease Academic Article
- The anticoagulant function of coagulation factor v Academic Article
- The frequency of type-I heterozygous protein-S and protein-C deficiency in 141 unrelated young-patients with venous thrombosis Academic Article
- The impact of fibrinolytic therapy for st-segment-elevation acute myocardial infarction Academic Article
- The relationship of obesity to ischemic outcomes following coronary stent placement in contemporary practice Academic Article
- Thrombin-specific anticoagulation with bivalirudin versus heparin in patients receiving fibrinolytic therapy for acute myocardial infarction: The hero-2 randomised trial Academic Article
- Tirofiban as adjunctive therapy for acute coronary syndromes and percutaneous coronary intervention: A meta-analysis of randomized trials Academic Article
- Tissue factor and protease-activated receptor signaling in cancer Academic Article
- Total chemical synthesis of enzymatically active human type II secretory phospholipase A2 Academic Article
- Trial of abciximab with and without low-dose reteplase for acute myocardial infarction Academic Article
- Upregulation of the antithrombotic protein C pathway at birth Academic Article
- Use of bedside activated partial thromboplastin time monitor to adjust heparin dosing after thrombolysis for acute myocardial infarction: Results of gusto-i Academic Article
- Use of bivalirudin during percutaneous coronary intervention in patients with diabetes mellitus - an analysis from the randomized evaluation in percutaneous coronary intervention linking angiomax to reduced clinical events (replace)-2 trial Academic Article
- Warfarin pharmacogenomics: A big step forward for individualized medicine: enlightened dosing of warfarin Academic Article
- Zn(2+)-containing protein S inhibits extrinsic factor X-activating complex independently of tissue factor pathway inhibitor Academic Article