recent publications

• academic article

  • Zhou, T., Lynch, R. M., Chen, L., Acharya, P., Wu, X., Doria-Rose, N. A., Joyce, M. G., Lingwood, D., Soto, C., Bailer, R. T., Ernandes, M. J., Kong, R., et al. Structural repertoire of HIV-1-neutralizing antibodies targeting the CD4 supersite in 14 donors Cell  2015 161:1280-1292  DOI:10.1016/j.cell.2015.05.007  PMID:26004070  PMCID:PMC4683157
  • Teixeira, L. K., Wang, X., Li, Y., Ekholm-Reed, S., Wu, X., Wang, P., Reed, S. I. Cyclin E deregulation promotes loss of specific genomic regions Current Biology  2015 25:1327-1333  DOI:10.1016/j.cub.2015.03.022  PMID:25959964  PMCID:PMC4439338
  • Zhu, J., Wu, X., Zhang, B., McKee, K., O'Dell, S., Soto, C., Zhou, T., Casazza, J. P., NISC Comparative Sequencing Program, Mullikin, J. C., Kwong, P. D., Mascola, J. R., et al. De novo identification of VRC01 class HIV-1-neutralizing antibodies by next-generation sequencing of B-cell transcripts Proceedings of the National Academy of Sciences of the United States of America  2013 110:E4088-E4097  DOI:10.1073/pnas.1306262110  PMID:24106303  PMCID:PMC3808619
  • Zhou, T., Zhu, J., Wu, X., Moquin, S., Zhang, B., Acharya, P., Georgiev, I. S., Altae-Tran, H. R., Chuang, G. Y., Joyce, M. G., Kwon, Y. D., Longo, N. S., et al. Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies Immunity  2013 39:245-258  DOI:10.1016/j.immuni.2013.04.012  PMID:23911655  PMCID:PMC3985390
  • Li, Y. X., O'Dell, S., Wilson, R., Wu, X., Schmidt, S. D., Hogerkorp, C. M., Louder, M. K., Longo, N. S., Poulsen, C., Guenaga, J., Chakrabarti, B. K., Doria-Rose, N., et al. Hiv-1 neutralizing antibodies display dual recognition of the primary and coreceptor binding sites and preferential binding to fully cleaved envelope glycoproteins Journal of Virology  2012 86:11231-11241  DOI:10.1128/jvi.01543-12  PMID:22875963  PMCID:PMC3457177
  • Wu, X., Wang, C., O'Dell, S., Li, Y. X., Keele, B. F., Yang, Z. J., Imamichi, H., Doria-Rose, N., Hoxie, J. A., Connors, M., Shaw, G. M., Wyatt, R. T., et al. Selection pressure on hiv-1 envelope by broadly neutralizing antibodies to the conserved cd4-binding site Journal of Virology  2012 86:5844-5856  DOI:10.1128/jvi.07139-11  PMID:22419808  PMCID:PMC3347292
  • Falkowska, E., Ramos, A., Feng, Y., Zhou, T. Q., Moquin, S., Walker, L. M., Wu, X., Seaman, M. S., Wrin, T., Kwong, P. D., Wyatt, R. T., Mascola, J. R., et al. PGV04, an HIV-1 gp120 CD4 binding site antibody, is broad and potent in neutralization but does not induce conformational changes characteristic of CD4 Journal of Virology  2012 86:4394-4403  DOI:10.1128/jvi.06973-11  PMID:22345481  PMCID:PMC3318667
  • Zhu, J., O'Dell, S., Ofek, G., Pancera, M., Wu, X., Zhang, B., Zhang, Z., NISC Comparative Sequencing Program, Mullikin, J. C., Simek, M., Burton, D. R., Koff, W. C., et al. Somatic populations of PGT135-137 HIV-1-neutralizing antibodies identified by 454 pyrosequencing and bioinformatics Frontiers in Microbiology  2012 3:315  DOI:10.3389/fmicb.2012.00315  PMID:23024643  PMCID:PMC3441199
  • Smith, B. J., Sutton, G. M., Wu, X., Yu, G., Goh, B. C., Hebert, T., Pelled, G., Gazit, Z., Gazit, D., Butler, A. A., Gimble, J. M. Ovariectomy and genes encoding core circadian regulatory proteins in murine bone Osteoporosis International  2011 22:1633-1639  DOI:10.1007/s00198-010-1325-z  PMID:20593165  PMCID:PMC4215737
  • Schoning, K. U., Scholz, P., Guntha, S., Wu, X., Krishnamurthy, R., Eschenmoser, A. Chemical etiology of nucleic acid structure: The alpha-threofuranosyl-(3 '-> 2 ') oligonucleotide system Science  2000 290:1347-1351  DOI:10.1126/science.290.5495.1347  PMID:11082060