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Transfer of pro alpha 2(i) cdna into cells of a murine model of human osteogenesis imperfecta restores synthesis of type i collagen comprised of alpha 1(i) and alpha 2(i) heterotrimers in vitro and in vivo

Academic Article
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Overview

authors

  • Niyibizi, C.
  • Smith, P.
  • Mi, Z. B.
  • Phillips, C. L.
  • Robbins, Paul D.

publication date

  • 2001

journal

  • Journal of Cellular Biochemistry  Journal

subject areas

  • Adenoviridae
  • Alkaline Phosphatase
  • Animals
  • Bone Marrow Cells
  • Bone Morphogenetic Protein 2
  • Bone Morphogenetic Proteins
  • Cells, Cultured
  • Collagen
  • DNA, Complementary
  • Disease Models, Animal
  • Gene Deletion
  • Genetic Therapy
  • Genetic Vectors
  • Humans
  • Mice
  • Osteogenesis Imperfecta
  • Pepsin A
  • Procollagen
  • Protein Structure, Quaternary
  • Recombinant Proteins
  • Stromal Cells
  • Transduction, Genetic
  • Transforming Growth Factor beta
  • Transgenes
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Research

keywords

  • bone marrow
  • collagen
  • gene therapy
  • gene transfer
  • osteogenesis imperfecta
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Identity

International Standard Serial Number (ISSN)

  • 0730-2312

Digital Object Identifier (DOI)

  • 10.1002/jcb.1209

PubMed ID

  • 11500956
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Additional Document Info

start page

  • 84

end page

  • 91

volume

  • 83

issue

  • 1

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