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Bupivacaine decreases cell viability and matrix protein synthesis in an intervertebral disc organ model system

Academic Article
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Overview

authors

  • Wang, D.
  • Vo, N. V.
  • Sowa, G. A.
  • Hartman, R. A.
  • Ngo, K.
  • Choe, S. R.
  • Witt, W. T.
  • Dong, Q.
  • Lee, Jiing-Dwan
  • Niedernhofer, Laura
  • Kang, J. D.

publication date

  • February 2011

journal

  • Spine Journal  Journal

subject areas

  • Anesthetics, Local
  • Animals
  • Bupivacaine
  • Cell Survival
  • Dose-Response Relationship, Drug
  • Extracellular Matrix
  • Extracellular Matrix Proteins
  • Intervertebral Disc
  • Lumbar Vertebrae
  • Mice
  • Organ Culture Techniques
  • Protein Biosynthesis
  • Time Factors
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Research

keywords

  • Bupivacaine
  • Cell viability
  • Disc organ culture
  • Local anesthetic
  • Matrix protein synthesis
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Identity

PubMed Central ID

  • PMC3056334

International Standard Serial Number (ISSN)

  • 1529-9430

Digital Object Identifier (DOI)

  • 10.1016/j.spinee.2010.11.017

PubMed ID

  • 21296298
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Additional Document Info

start page

  • 139

end page

  • 146

volume

  • 11

issue

  • 2

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