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Synthesis and evaluation of 1-(substituted)-3-prop-2-ynylureas as antiangiogenic agents

Academic Article
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Overview

authors

  • Sanphanya, K.
  • Wattanapitayakul, S. K.
  • Prangsaengtong, O.
  • Jo, M.
  • Koizumi, K.
  • Shibahara, N.
  • Priprem, A.
  • Fokin, Valery
  • Vajragupta, O.

publication date

  • April 2012

journal

  • Bioorganic & Medicinal Chemistry Letters  Journal

subject areas

  • Angiogenesis Inhibitors
  • Binding Sites
  • Breast Neoplasms
  • Cell Line, Tumor
  • Cell Proliferation
  • Female
  • HeLa Cells
  • Humans
  • Inhibitory Concentration 50
  • Models, Molecular
  • Urea
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Research

keywords

  • 1-(Substituted)-3-prop-2-ynylurea
  • Antiangiogenic agent
  • Cytotoxic agents
  • EGFR kinase inhibitor
  • Tyrosine kinase inhibitors
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Identity

International Standard Serial Number (ISSN)

  • 0960-894X

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2012.02.029

PubMed ID

  • 22414612
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Additional Document Info

start page

  • 3001

end page

  • 3005

volume

  • 22

issue

  • 8

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