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In vivo expression of HGF/NK1 and GLP-1 from dsAAV vectors enhances pancreatic beta-cell proliferation and improves pathology in the db/db mouse model of diabetes

Academic Article
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Overview

authors

  • Gaddy, D. F.
  • Riedel, M. J.
  • Pejawar-Gaddy, S.
  • Kieffer, T. J.
  • Robbins, Paul D.

publication date

  • December 2010

journal

  • Diabetes  Journal

subject areas

  • Animals
  • Cell Division
  • DNA Primers
  • Dependovirus
  • Diabetes Mellitus, Experimental
  • Diabetes Mellitus, Type 2
  • Female
  • Genes, Reporter
  • Genetic Vectors
  • Glucagon-Like Peptide 1
  • Green Fluorescent Proteins
  • Hepatocyte Growth Factor
  • Insulin-Secreting Cells
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Peptide Fragments
  • Plasmids
  • Polymerase Chain Reaction
  • Recombinant Proteins
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Identity

PubMed Central ID

  • PMC2992772

International Standard Serial Number (ISSN)

  • 0012-1797

Digital Object Identifier (DOI)

  • 10.2337/db09-1886

PubMed ID

  • 20841608
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Additional Document Info

start page

  • 3108

end page

  • 3116

volume

  • 59

issue

  • 12

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