recent publications

• academic article

  • Tilstra, J. S., Gaddy, D. F., Zhao, J., Dave, S. H., Niedernhofer, L. J., Plevy, S. E., Robbins, P. D. Pharmacologic IKK/NF-kappa B inhibition causes antigen presenting cells to undergo TNF alpha dependent ROS-mediated programmed cell death Scientific Reports  2014 4:3631  DOI:10.1038/srep03631  PMID:24406986  PMCID:PMC3887388
  • Gaddy, D. F., Riedel, M. J., Bertera, S., Kieffer, T. J., Robbins, P. D. DsAAV8-mediated gene transfer and beta-cell expression of IL-4 and beta-cell growth factors are capable of reversing early-onset diabetes in NOD mice Gene Therapy  2012 19:791-799  DOI:10.1038/gt.2011.181  PMID:22089495
  • Riedel, M. J., Gaddy, D. F., Asadi, A., Robbins, P. D., Kieffer, T. J. DsAAV8-mediated expression of glucagon-like peptide-1 in pancreatic beta-cells ameliorates streptozotocin-induced diabetes Gene Therapy  2010 17:171-180  DOI:10.1038/gt.2009.143  PMID:19865180
  • Gaddy, D. F., Riedel, M. J., Pejawar-Gaddy, S., Kieffer, T. J., Robbins, P. D. In vivo expression of HGF/NK1 and GLP-1 from dsAAV vectors enhances pancreatic beta-cell proliferation and improves pathology in the db/db mouse model of diabetes Diabetes  2010 59:3108-3116  DOI:10.2337/db09-1886  PMID:20841608  PMCID:PMC2992772