recent publications

• academic article

  • Yakovleva, T., Marinova, Z., Kumin, A., Seidah, N. G., Haroutunian, V., Terenius, L., Bakalkin, G. Dysregulation of dynorphins in alzheimer disease Neurobiology of Aging  2007 28:1700-1708  DOI:10.1016/j.neurobiolaging.2006.07.002  PMID:16914231
  • Okvist, A., Johansson, S., Kuzmin, A., Bazov, I., Merino-Martinez, R., Ponomarev, I., Mayfield, R. D., Harris, R. A., Sheedy, D., Garrick, T., Harper, C., Hurd, Y. L., et al. Neuroadaptations in human chronic alcoholics: Dysregulation of the nf-kappa b system PLoS One  2007 2:e930  DOI:10.1371/journal.pone.0000930  PMID:17895971  PMCID:PMC1976556
  • Yakovleva, T., Bazov, I., Cebers, G., Marinova, Z., Hara, Y., Ahmed, A., Vlaskovska, M., Johansson, B. R., Hochgeschwender, U., Singh, I. N., Bruce-Keller, A. J., Hurd, Y. L., et al. Prodynorphin storage and processing in axon terminals and dendrites FASEB Journal  2006 20:2124-6  DOI:10.1096/fj.06-6174fje  PMID:16966485
  • Marinova, Z., Vukojevic, V., Surcheva, S., Yakovleva, T., Cebers, G., Pasikova, N., Usynin, I., Hugonin, L., Fang, W. J., Hallberg, M., Hirschberg, D., Bergman, T., et al. Translocation of dynorphin neuropeptides across the plasma membrane - a putative mechanism of signal transmission Journal of Biological Chemistry  2005 280:26360-26370  DOI:10.1074/jbc.M412494200  PMID:15894804
  • Nikoshkov, A., Hurd, Y. L., Yakovleva, T., Bazov, I., Marinova, Z., Cebers, G., Pasikova, N., Gharibyan, A., Terenius, L., Bakalkin, G. Prodynorphin transcripts and proteins differentially expressed and regulated in the adult human brain FASEB Journal  2005 19:1543-5  DOI:10.1096/fj.05-3743fje  PMID:16014400
  • Vukojevic, V., Pramanik, A., Yakovleva, T., Rigler, R., Terenius, L., Bakalkin, G. Study of molecular events in cells by fluorescence correlation spectroscopy Cellular and Molecular Life Sciences  2005 62:535-550  DOI:10.1007/s00018-004-4305-7  PMID:15747060
  • Tan-No, K., Takahashi, H., Nakagawasai, O., Niijima, F., Sato, T., Satoh, S., Sakurada, S., Marinova, Z., Yakovleva, T., Bakalkin, G., Terenius, L., Tadano, T. Pronociceptive role of dynorphins in uninjured animals: N-ethylmaleimide-induced nociceptive behavior mediated through inhibition of dynorphin degradation Pain  2005 113:301-309  DOI:10.1016/j.pain.2004.11.004  PMID:15661437
  • Yakovleva, T., Kolesnikova, L., Vukojevic, V., Gileva, I., Tan-No, K., Austen, M., Luscher, B., Ekstrom, T. J., Terenius, L., Bakalkin, G. Yy1 binding to a subset of p53 DNA-target sites regulates p53-dependent transcription Biochemical and Biophysical Research Communications  2004 318:615-624  DOI:10.1016/j.bbrc.2004.04.065  PMID:15120643
  • Vukojevic, V., Yakovleva, T., Terenius, L., Pramanik, A., Bakalkin, G. Denaturation of dsdna by p53: Fluorescence correlation spectroscopy study Biochemical and Biophysical Research Communications  2004 316:1150-1155  DOI:10.1016/j.bbrc.2004.02.167  PMID:15044105
  • Yakovleva, T., Pramanik, A., Terenius, L., Ekstrom, T. J., Bakalkin, G. P53 latency - out of the blind alley Trends in Biochemical Sciences  2002 27:612-618  DOI:10.1016/s0968-0004(02)02209-0  PMID:12468230
  • Tan-No, K., Cebers, G., Yakovleva, T., Goh, B. H., Gileva, I., Reznikov, K., Aguilar-Santelises, M., Hauser, K. F., Terenius, L., Bakalkin, G. Cytotoxic effects of dynorphins through nonopioid intracellular mechanisms Experimental Cell Research  2001 269:54-63  DOI:10.1006/excr.2001.5309  PMID:11525639
  • Yakovleva, T., Pramanik, A., Kawasaki, T., Tan-No, K., Gileva, I., Lindgren, H., Langel, U., Ekstrom, T. J., Rigler, R., Terenius, L., Bakalkin, G. P53 latency - c-terminal domain prevents binding of p53 core to target but not to nonspecific DNA sequences Journal of Biological Chemistry  2001 276:15650-15658  DOI:10.1074/jbc.M100482200  PMID:11279079
  • Reznikov, K., Kolesnikova, L., Pramanik, A., Tan-no, K., Gileva, I., Yakovleva, T., Rigler, R., Terenius, L., Bakalkin, G. Clustering of apoptotic cells via bystander killing by peroxides FASEB Journal  2000 14:1754-1764  DOI:10.1096/fj.99-0890com  PMID:10973925
  • Hurd, Y. L., Yakovleva, T., Nussenzweig, A., Li, G. C., Terenius, L., Bakalkin, G. A novel neuron-specific DNA end-binding factor in the murine brain Molecular and Cellular Neuroscience  1999 14:213-224  DOI:10.1006/mcne.1999.0782  PMID:10576891
  • Bakalkin, G., Yakovleva, T., Hurd, Y. L., Nussenzweig, A., Li, G. C., Terenius, L. Autoantigen ku in the brain. Developmentally regulated expression and subcellular localization Neuroreport  1998 9:2147-2151  DOI:10.1097/00001756-199806220-00044  PMID:9674610
  • Bakalkin, G., Yakovleva, T., Melzig, M., Terenius, L. Long-term morphine treatment increases ku protein DNA end-binding activity Neuroreport  1997 8:2143-2148  PMID:9243600
  • Bakalkin, G., Yakovleva, T., Terenius, L. The leu-enkephalin-encoding sequence DNA-binding factor (lef) is the transcription factor yy1 Biochemical and Biophysical Research Communications  1997 231:135-139  DOI:10.1006/bbrc.1997.6062  PMID:9070235
  • Bakalkin, G., Telkov, M., Yakovleva, T., Terenius, L. Leu5enkephalin-encoding sequences are targets for a specific DNA-binding factor. Proceedings of the National Academy of Sciences of the United States of America  1995 92:9024-9028  DOI:10.1073/pnas.92.20.9024  PMID:7568065  PMCID:PMC40916
  • Bakalkin, G., Selivanova, G., Yakovleva, T., Kiseleva, E., Kashuba, E., Magnusson, K. P., Szekely, L., Klein, G., Terenius, L., Wiman, K. G. P53 binds single-stranded DNA ends through the c-terminal domain and internal DNA segments via the middle domain Nucleic Acids Research  1995 23:362-369  DOI:10.1093/nar/23.3.362  PMID:7885831  PMCID:PMC306684
  • Bakalkin, G., Yakovleva, T., Terenius, L. Prodynorphin gene-expression relates to nf-kappa-b factors Molecular Brain Research  1994 24:301-312  DOI:10.1016/0169-328x(94)90143-0  PMID:7968369
  • Bakalkin, G., Yakovleva, T., Selivanova, G., Magnusson, K. P., Szekely, L., Kiseleva, E., Klein, G., Terenius, L., Wiman, K. G. P53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer Proceedings of the National Academy of Sciences of the United States of America  1994 91:413-417  DOI:10.1073/pnas.91.1.413  PMID:8278402  PMCID:PMC42958
  • Bakalkin, G. Y., Yakovleva, T., Terenius, L. Nf-kappa-b-like factors in the murine brain - developmentally-regulated and tissue-specific expression Molecular Brain Research  1993 20:137-146  DOI:10.1016/0169-328x(93)90119-a  PMID:8255175