recent publications

• academic article

  • Doshi, N., Orje, J. N., Molins, B., Smith, J. W., Mitragotri, S., Ruggeri, Z. M. Platelet mimetic particles for targeting thrombi in flowing blood Advanced Materials  2012 24:3864-3869  DOI:10.1002/adma.201200607  PMID:22641451  PMCID:PMC3483800
  • Aleshin, A. E., Gramatikova, S., Hura, G. L., Bobkov, A., Strongin, A. Y., Stec, B., Tainer, J. A., Liddington, R. C., Smith, J. W. Crystal and solution structures of a prokaryotic m16b peptidase: An open and shut case Structure  2009 17:1465-1475  DOI:10.1016/j.str.2009.09.009  PMID:19913481  PMCID:PMC3615642
  • Chen, E. I., Florens, L., Axelrod, F. T., Monosov, E., Barbas, C. F., Yates, J. R., Felding-Habermann, B., Smith, J. W. Maspin alters the carcinoma proteome FASEB Journal  2005 19:1123-1124  DOI:10.1096/fj.04-2970fje  PMID:15857880
  • Ratnikov, B. I., Rozanov, D. V., Postnova, T. I., Baciu, P. G., Zhang, H., DiScipio, R. G., Chestukhina, G. G., Smith, J. W., Deryugina, E. I., Strongin, A. Y. An alternative processing of integrin αv subunit in tumor cells by membrane type-1 matrix metalloproteinase Journal of Biological Chemistry  2002 277:7377-7385  DOI:10.1074/jbc.M109580200  PMID:11741954
  • Deryugina, E. I., Ratnikov, B., Monosov, E., Postnova, T. I., DiScipio, R., Smith, J. W., Strongin, A. Y. MT1-MMP initiates activation of pro-MMP-2 and integrin αvβ3 promotes maturation of MMP-2 in breast carcinoma cells Experimental Cell Research  2001 263:209-223  DOI:10.1006/excr.2000.5118  PMID:11161720
  • Felding-Habermann, B., O'Toole, T. E., Smith, J. W., Fransvea, E., Ruggeri, Z. M., Ginsberg, M. H., Hughes, P. E., Pampori, N., Shattil, S. J., Saven, A., Mueller, B. M. Integrin activation controls metastasis in human breast cancer Proceedings of the National Academy of Sciences of the United States of America  2001 98:1853-1858  DOI:10.1073/pnas.98.4.1853  PMID:11172040  PMCID:PMC29346
  • Deryugina, E. I., Bourdon, M. A., Jungwirth, K., Smith, J. W., Strongin, A. Y. Functional activation of integrin αvβ3 in tumor cells expressing membrane-type 1 matrix metalloproteinase International Journal of Cancer  2000 86:15-23  DOI:10.1002/(sici)1097-0215(20000401)86:1<15::aid-ijc3>3.0.co;2-b  PMID:10728589
  • Wong, N. C., Mueller, B. M., Barbas, C. F., Ruminski, P., Quaranta, V., Lin, E. C. K., Smith, J. W. Alpha(v) integrins mediate adhesion and migration of breast carcinoma cell lines Clinical & Experimental Metastasis  1998 16:50-61  PMID:9502077
  • Lin, E. C. K., Ratnikov, B. I., Tsai, P. M., Carron, C. P., Myers, D. M., Barbas, C. F., Smith, J. W. Identification of a region in the integrin beta 3 subunit that confers ligand binding specificity Journal of Biological Chemistry  1997 272:23912-23920  DOI:10.1074/jbc.272.38.23912  PMID:9295341
  • Hu, D. D., Barbas, C. F., Smith, J. W. An allosteric ca2+ binding site on the beta 3 integrins that regulates the dissociation rate for rgd ligands Journal of Biological Chemistry  1996 271:21745-21751  PMID:8702970
  • Stuiver, I., Ruggeri, Z., Smith, J. W. Divalent cations regulate the organization of integrins alpha v beta 3 and alpha v beta 5 on the cell surface Journal of Cellular Physiology  1996 168:521-531  DOI:10.1002/(sici)1097-4652(199609)168:3<521::aid-jcp4>3.0.co;2-r  PMID:8816906
  • Smith, J. W., Hu, D., Satterthwait, A., Pinzsweeney, S., Barbas, C. F. Building synthetic antibodies as adhesive ligands for integrins Journal of Biological Chemistry  1994 269:32788-32795  PMID:7806501
  • Bowditch, R. D., Hariharan, M., Tominna, E. F., Smith, J. W., Yamada, K. M., Getzoff, E. D., Ginsberg, M. H. Identification of a novel integrin binding-site in fibronectin - differential utilization by beta-3 integrins Journal of Biological Chemistry  1994 269:10856-10863  PMID:7511609
  • Barbas, C. F., Languino, L. R., Smith, J. W. High-affinity self-reactive human-antibodies by design and selection - targeting the integrin ligand-binding site Proceedings of the National Academy of Sciences of the United States of America  1993 90:10003-10007  PMID:7694276  PMCID:PMC47701
  • Smith, J. W., Ruggeri, Z. M., Kunicki, T. J., Cheresh, D. A. Interaction of integrins alpha v beta 3 and glycoprotein IIb-IIIa with fibrinogen. Differential peptide recognition accounts for distinct binding sites Journal of Biological Chemistry  1990 265:12267-12271  PMID:2373693