recent publications

• academic article

  • Lohman, J. R., Ma, M., Osipiuk, J., Nocek, B., Kim, Y., Chang, C., Cuff, M., Mack, J., Bigelow, L., Li, H., Endres, M., Babnigg, G., et al. Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases Proceedings of the National Academy of Sciences of the United States of America  2015 112:12693-12698  DOI:10.1073/pnas.1515460112  PMID:26420866  PMCID:PMC4611616
  • Brennand, K., Savas, J. N., Kim, Y., Tran, N., Simone, A., Hashimoto-Torii, K., Beaumont, K. G., Kim, H. J., Topol, A., Ladran, I., Abdelrahim, M., Matikainen-Ankney, B., et al. Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia Molecular Psychiatry  2015 20:361-368  DOI:10.1038/mp.2014.22  PMID:24686136  PMCID:PMC4182344
  • Lee, S. H., Ripke, S., Neale, B. M., Faraone, S. V., Purcell, S. M., Perlis, R. H., Mowry, B. J., Thapar, A., Goddard, M. E., Witte, J. S., Absher, D., Agartz, I., et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs Nature Genetics  2013 45:984-994  DOI:10.1038/ng.2711  PMID:23933821  PMCID:PMC3800159
  • Wu, R., Gu, M., Wilton, R., Babnigg, G., Kim, Y., Pokkuluri, P. R., Szurmant, H., Joachimiak, A., Schiffer, M. Insight into the sporulation phosphorelay: Crystal structure of the sensor domain of Bacillus subtilis histidine kinase, KinD Protein Science  2013 22:564-576  DOI:10.1002/pro.2237  PMID:23436677  PMCID:PMC3649258
  • Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., Ahn, H. J., Ait-Mohamed, O., et al. Guidelines for the use and interpretation of assays for monitoring autophagy Autophagy  2012 8:445-544  DOI:10.4161/auto.19496  PMID:22966490  PMCID:PMC3404883
  • Ripke, S., Sanders, A. R., Kendler, K. S., Levinson, D. F., Sklar, P., Holmans, P. A., Lin, D. Y., Duan, J., Ophoff, R. A., Andreassen, O. A., Scolnick, E., Cichon, S., et al. Genome-wide association study identifies five new schizophrenia loci Nature Genetics  2011 43:969-76  DOI:10.1038/ng.940  PMID:21926974  PMCID:PMC3303194
  • Hwang, J., Kim, Y., Kang, H. B., Jaroszewski, L., Deacon, A. M., Lee, H., Choi, W. C., Kim, K. J., Kim, C. H., Kang, B. S., Lee, J. O., Oh, T. K., et al. Crystal structure of the human n-myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor Journal of Biological Chemistry  2011 286  DOI:10.1074/jbc.M110.170803  PMID:21247902  PMCID:PMC3069448
  • Kim, S., Takahashi, H., Lin, W. W., Descargues, P., Grivennikov, S., Kim, Y., Luo, J. L., Karin, M. Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis Nature  2009 457:102-106  DOI:10.1038/nature07623  PMID:19122641  PMCID:PMC2746432
  • Graslund, S., Nordlund, P., Weigelt, J., Bray, J., Hallberg, B. M., Gileadi, O., Knapp, S., Oppermann, U., Arrowsmith, C., Hui, R., Ming, J., Dhe-Paganon, S., et al. Protein production and purification Nature Methods  2008 5:135-146  DOI:10.1038/nmeth.f.202  PMID:18235434  PMCID:PMC3178102
  • Nettles, K. W., Bruning, J. B., Gil, G., Nowak, J., Sharma, S. K., Hahm, J. B., Kulp, K., Hochberg, R. B., Zhou, H., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Kim, Y., et al. NF kappa B selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses Nature Chemical Biology  2008 4:241-247  DOI:10.1038/nchembio.76  PMID:18344977  PMCID:PMC2659626
  • Zhou, H. B., Nettles, K. W., Bruning, J. B., Kim, Y., Joachimiak, A., Sharma, S., Carlson, K. E., Stossi, F., Katzenellenbogen, B. S., Greene, G. L., Katzenellenbogen, J. A. Elemental isomerism: A boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands Chemistry & Biology  2007 14:659-669  DOI:10.1016/j.chembiol.2007.04.009  PMID:17584613
  • Zhou, H. B., Sheng, S. B., Compton, D. R., Kim, Y., Joachimiak, A., Sharma, S., Carlson, K. E., Katzenellenbogen, B. S., Nettles, K. W., Greene, G. L., Katzenellenbogen, J. A. Structure-guided optimization of estrogen receptor binding affinity and antagonist potency of pyrazolopyrimidines with basic side chains Journal of Medicinal Chemistry  2007 50:399-403  DOI:10.1021/jm061035y  PMID:17228884
  • Nettles, K. W., Bruning, J. B., Gil, G., O'Neill, E. E., Nowak, J., Guo, Y., Kim, Y., DeSombre, E. R., Dilis, R., Hanson, R. N., Joachimiak, A., Greene, G. L. Structural plasticity in the oestrogen receptor ligand-binding domain EMBO Reports  2007 8:563-568  DOI:10.1038/sj.embor.7400963  PMID:17468738  PMCID:PMC2002528
  • Baek, M. C., Kim, S. J., Yea, K., Kim, Y., Lee, B. D., Kim, J., Lee, H. J., Kang, M. H., Choi, S. K., Kim, J. I., Lee, T. G., Suh, P. G., et al. Ligand profiling and identification technology for searching bioactive ligands Proteomics  2006 6:1741-1749  DOI:10.1002/pmic.200500511  PMID:16526000
  • Kim, Y., Leconte, A. M., Hari, Y., Romesberg, F. E. Stability and polymerase recognition of pyridine nucleobase analogues: Role of minor-groove h-bond acceptors Angewandte Chemie-International Edition  2006 45:7809-7812  DOI:10.1002/anie.200602579  PMID:17075934
  • Kops, G. J. P. L, Kim, Y., Weaver, B. A. A., Mao, Y. H., McLeod, I., Yates, J. R., Tagaya, M., Cleveland, D. W. ZW10 links mitotic checkpoint signaling to the structural kinetochore Journal of Cell Biology  2005 169:49-60  DOI:10.1083/jcb.200411118  PMID:15824131  PMCID:PMC1351127
  • Tasic, B., Nabholz, C. E., Baldwin, K. K., Kim, Y., Rueckert, E. H., Ribich, S. A., Cramer, P., Wu, Q., Axel, R., Maniatis, T. Promoter choice determines splice site selection in protocadherin alpha and -gamma pre-mRNA splicing Molecular Cell  2002 10:21-33  DOI:10.1016/s1097-2765(02)00578-6  PMID:12150904
  • Conti, B., Sugama, S., Kim, Y., Tinti, C., Kim, H., Baker, H., Volpe, B., Attardi, B., Joh, T. Modulation of IL-18 production in the adrenal cortex following acute ACTH or chronic corticosterone treatment Neuroimmunomodulation  2000 8:1-7  DOI:10.1159/000026445  PMID:10859481
  • Conti, B., Park, L. C. H., Calingasan, N. Y., Kim, Y., Kim, H., Bae, Y., Gibson, G. E., Joh, T. H. Cultures of astrocytes and microglia express interleukin 18 Molecular Brain Research  1999 67:46-52  DOI:10.1016/s0169-328x(99)00034-0  PMID:10101231
  • Kim, Y., Babcock, G. T., Surerus, K. K., Fee, J. A., Dyer, R. B., Woodruff, W. H., Oertling, W. A. Cyanide binding and active site structure in heme-copper oxidases: Normal coordinate analysis of iron-cyanide vibrations of a(3)(2+)cn(-) complexes of cytochromes ba(3) and aa(3) Biospectroscopy  1998 4:1-15  DOI:10.1002/(sici)1520-6343(1998)4:1<1::aid-bspy1>3.0.co;2-a  PMID:9547010