recent publications

• academic article

  • Yea, K., Xie, J., Zhang, H., Zhang, W., Lerner, R. A. Selection of multiple agonist antibodies from intracellular combinatorial libraries reveals that cellular receptors are functionally pleiotropic Current Opinion in Chemical Biology  2015 26:1-7  DOI:10.1016/j.cbpa.2015.01.002  PMID:25621729
  • Zhang, J., Zhang, K., Gao, Z. G., Paoletta, S., Zhang, D., Han, G. W., Li, T., Ma, L., Zhang, W., Muller, C. E., Yang, H., Jiang, H., et al. Agonist-bound structure of the human P2Y(12) receptor Nature  2014 509:119-122  DOI:10.1038/nature13288  PMID:24784220  PMCID:PMC4128917
  • Zhang, K., Zhang, J., Gao, Z. G., Zhang, D., Zhu, L., Han, G. W., Moss, S. M., Paoletta, S., Kiselev, E., Lu, W., Fenalti, G., Zhang, W., et al. Structure of the human P2Y(12) receptor in complex with an antithrombotic drug Nature  2014 509:115-118  DOI:10.1038/nature13083  PMID:24670650  PMCID:PMC4174307
  • Tan, Q., Zhu, Y., Li, J., Chen, Z., Han, G. W., Kufareva, I., Li, T., Ma, L., Fenalti, G., Li, J., Zhang, W., Xie, X., et al. Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex Science  2013 341:1387-1390  DOI:10.1126/science.1241475  PMID:24030490  PMCID:PMC3819204
  • Nangle, L. A., Zhang, W., Xie, W., Yang, X. L., Schimmel, P. Charcot-Marie-Tooth disease-associated mutant tRNA synthetases linked to altered dimer interface and neurite distribution defect Proceedings of the National Academy of Sciences of the United States of America  2007 104:11239-11244  DOI:10.1073/pnas.0705055104  PMID:17595294  PMCID:PMC2040883
  • Xie, W., Nangle, L. A., Zhang, W., Schimmel, P., Yang, X. L. Long-range structural effects of a Charcot-Marie-Tooth disease-causing mutation in human glycyl-tRNA synthetase Proceedings of the National Academy of Sciences of the United States of America  2007 104:9976-9981  DOI:10.1073/pnas.0703908104  PMID:17545306  PMCID:PMC1891255
  • Hao, X. S., Sun, B. C., Hu, L. M., Lahdesmaki, H., Dunmire, V., Feng, Y. M., Zhang, S. W., Wang, H. M., Wu, C. L., Wang, H., Fuller, G. N., Symmans, W. F., et al. Differential gene and protein expression in primary breast malignancies and their lymph node metastases as revealed by combined cdna microarray and tissue microarray analysis Cancer  2004 100:1110-1122  DOI:10.1002/cncr.20095  PMID:15022276
  • Dunmire, V., Wu, C. L., Symmans, W. F., Zhang, W. Increased yield of total rna from fine-needle aspirates for use in expression microarray analysis Biotechniques  2002 33:890-892, 894, 866  PMID:12398198
  • Petra, P. H., Griffin, P. R., Yates, J. R., Moore, K., Zhang, W. Complete enzymatic deglycosylation of native sex steroid-binding protein (SBP or SHBG) of human and rabbit plasma: effect on the steroid-binding activity Protein Science  1992 1:902-909  DOI:10.1002/pro.5560010708  PMID:1304375  PMCID:PMC2142156