recent publications

• academic article

  • Guttman, M., Cupo, A., Julien, J. P., Sanders, R. W., Wilson, I. A., Moore, J. P., Lee, K. K. Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env Nature Communications  2015 6:6144  DOI:10.1038/ncomms7144  PMID:25652336  PMCID:PMC4338595
  • Sanders, R. W., van Gils, M. J., Derking, R., Sok, D., Ketas, T. J., Burger, J. A., Ozorowski, G., Cupo, A., Simonich, C., Goo, L., Arendt, H., Kim, H. J., et al. HIV-1 neutralizing antibodies induced by native-like envelope trimers Science  2015 349:aac4223  DOI:10.1126/science.aac4223  PMID:26089353  PMCID:PMC4498988
  • Guttman, M., Garcia, N. K., Cupo, A., Matsui, T., Julien, J. P., Sanders, R. W., Wilson, I. A., Moore, J. P., Lee, K. K. CD4-induced activation in a soluble HIV-1 Env trimer Structure  2014 22:974-984  DOI:10.1016/j.str.2014.05.001  PMID:24931470  PMCID:PMC4231881
  • Huang, R. K., Khayat, R., Lee, K. K., Gertsman, I., Duda, R. L., Hendrix, R. W., Johnson, J. E. The prohead-i structure of bacteriophage hk97: Implications for scaffold-mediated control of particle assembly and maturation Journal of Molecular Biology  2011 408:541-554  DOI:10.1016/j.jmb.2011.01.016  PMID:21276801  PMCID:PMC3075369
  • Tang, J. H., Lee, K. K., Bothner, B., Baker, T. S., Yeager, M., Johnson, J. E. Dynamics and stability in maturation of a T = 4 virus Journal of Molecular Biology  2009 392:803-812  DOI:10.1016/j.jmb.2009.07.038  PMID:19627990  PMCID:PMC2766526
  • Lee, K. K., Gan, L., Tsuruta, H., Moyer, C., Conway, J. F., Duda, R. L., Hendrix, R. W., Steven, A. C., Johnson, J. E. Virus capsid expansion driven by the capture of mobile surface loops Structure  2008 16:1491-1502  DOI:10.1016/j.str.2008.06.014  PMID:18940605  PMCID:PMC2586091
  • Wikoff, W. R., Conway, J. F., Tang, J. H., Lee, K. K., Gan, L., Cheng, N. Q., Duda, R. L., Hendrix, R. W., Steven, A. C., Johnson, J. E. Time-resolved molecular dynamics of bacteriophage hk97 capsid maturation interpreted by electron cryo-microscopy and x-ray crystallography Journal of Structural Biology  2006 153:300-306  DOI:10.1016/j.jsb.2005.11.009  PMID:16427314
  • Lee, K. K., Tsuruta, H., Hendrix, R. W., Duda, R. L., Johnson, J. E. Cooperative reorganization of a 420 subunit virus capsid Journal of Molecular Biology  2005 352:723-735  DOI:10.1016/j.jmb.2005.07.024  PMID:16095623
  • Carrozza, M. J., Li, B., Florens, L., Suganuma, T., Swanson, S. K., Lee, K. K., Shia, W. J., Anderson, S., Yates, J., Washburn, M. P., Workman, J. L. Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription Cell  2005 123:581-592  DOI:10.1016/j.cell.2005.10.023  PMID:16286007
  • Bothner, B., Taylor, D., Jun, B., Lee, K. K., Siuzdak, G., Schlutz, C. P., Johnson, J. E. Maturation of a tetravirus capsid alters the dynamic properties and creates a metastable complex Virology  2005 334:17-27  DOI:10.1016/j.virol.2005.01.017  PMID:15749119
  • Lee, K. K., Gan, L., Tsuruta, H., Hendrix, R. W., Duda, R. L., Johnson, J. E. Evidence that a local refolding event triggers maturation of hk97 bacteriophage capsid Journal of Molecular Biology  2004 340:419-433  DOI:10.1016/j.jmc.2004.05.008  PMID:15210344
  • Lee, K. K., Tang, J. H., Taylor, D., Bothner, B., Johnson, J. E. Small compounds targeted to subunit interfaces arrest maturation in a nonenveloped, icosahedral animal virus Journal of Virology  2004 78:7208-7216  DOI:10.1128/jvi.78.13.7208.7216.2004  PMID:15194797
  • Lee, K. K., Johnson, J. E. Complementary approaches to structure determination of icosahedral viruses Current Opinion in Structural Biology  2003 13:558-569  DOI:10.1016/j.sbi.2003.09.007  PMID:14568610