Ruthenium-catalyzed cycloaddition of aryl azides and alkynes

Academic Article
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publication date

  • December 2007

abstract

  • The formation of 1,5-disubstituted 1,2,3-triazoles from aryl azides and alkynes was readily accomplished using [Cp*RuCl]4 catalyst in dimethylformamide. It was also demonstrated that the reaction provided higher yields, cleaner product, and shorter reaction times when carried out under microwave irradiation.