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Ruthenium-catalyzed cycloaddition of aryl azides and alkynes

Academic Article
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Overview

authors

  • Rasmussen, L. K.
  • Boren, B. C.
  • Fokin, Valery

publication date

  • December 2007

journal

  • Organic Letters  Journal

abstract

  • The formation of 1,5-disubstituted 1,2,3-triazoles from aryl azides and alkynes was readily accomplished using [Cp*RuCl]4 catalyst in dimethylformamide. It was also demonstrated that the reaction provided higher yields, cleaner product, and shorter reaction times when carried out under microwave irradiation.

subject areas

  • Alkynes
  • Azides
  • Catalysis
  • Cyclization
  • Ruthenium
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Identity

International Standard Serial Number (ISSN)

  • 1523-7060

Digital Object Identifier (DOI)

  • 10.1021/ol701912s

PubMed ID

  • 18052070
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Additional Document Info

start page

  • 5337

end page

  • 5339

volume

  • 9

issue

  • 26

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