Synthesis of the C(43)-C(67) fragment of amphidinol 3

Academic Article
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publication date

  • November 2005

abstract

  • [reaction: see text] A synthesis of the C(43)-C(67) fragment of amphidinol 3 (AM3) has been accomplished by a route that features the use of a double allylboration reaction for synthesis of 1,5-diol 4b, which serves as a precursor to dihydropyran 11.