recent publications

• academic article

  • Lee, P., Hsu, M. H., Welser-Alves, J., Peng, H. F. Severe microcytic anemia but increased erythropoiesis in mice lacking hfe or tfr2 and tmprss6 Blood Cells Molecules and Diseases  2012 48:173-178  DOI:10.1016/j.bcmd.2011.12.005  PMID:22244935  PMCID:PMC3294186
  • Truksa, J., Gelbart, T., Peng, H. F., Beutler, E., Beutler, B., Lee, P. Suppression of the hepcidin-encoding gene hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/tmprss6 British Journal of Haematology  2009 147:571-581  DOI:10.1111/j.1365-2141.2009.07873.x  PMID:19751239
  • Truksa, J., Lee, P., Peng, H. F., Flanagan, J., Beutler, E. The distal location of the iron responsive region of the hepcidin promoter Blood  2007 110:3436-3437  DOI:10.1182/blood-2007-05-091108  PMID:17644736  PMCID:PMC2200907
  • Truksa, J., Peng, H. F., Lee, P., Beutler, E. Different regulatory elements are required for response of hepcidin to interleukin-6 and bone morphogenetic proteins 4 and 9 British Journal of Haematology  2007 139:138-147  DOI:10.1111/j.1365-2141.2007.06728.x  PMID:17854319
  • Flanagan, J. M., Truksa, J., Peng, H. F., Lee, P., Beutler, E. In vivo imaging of hepcidin promoter stimulation by iron and inflammation Blood Cells Molecules and Diseases  2007 38:253-257  DOI:10.1016/j.bcmd.2007.01.004  PMID:17331760  PMCID:PMC1924465
  • Truksa, J., Peng, H. F., Lee, P., Beutler, E. Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of hfe, transferrin receptor 2 (tfr2), and il-6 Proceedings of the National Academy of Sciences of the United States of America  2006 103:10289-10293  DOI:10.1073/pnas.0603124103  PMID:16801541  PMCID:PMC1502450
  • Flanagan, J. M., Peng, H. F., Wang, L., Gelbart, T., Lee, P., Sasu, B. J., Beutler, E. Soluble transferrin receptor-1 levels in mice do not affect iron absorption Acta Haematologica  2006 116:249-254  DOI:10.1159/000095875  PMID:17119325
  • Lee, P., Peng, H. F., Gelbart, T., Wang, L., Beutler, E. Regulation of hepcidin transcription by interleukin-1 and interleukin-6 Proceedings of the National Academy of Sciences of the United States of America  2005 102:1906-1910  DOI:10.1073/pnas.0409808102  PMID:15684062  PMCID:PMC548537
  • Lee, P., Peng, H. F., Gelbart, T., Beutler, E. The il-6- and lipopolysaccharide-induced transcription of hepcidin in hfe-, transferrin receptor 2-, and beta(2)-microglobulin-deficient hepatocytes Proceedings of the National Academy of Sciences of the United States of America  2004 101:9263-9265  DOI:10.1073/pnas.0403108101  PMID:15192150  PMCID:PMC438964