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Jones, J. E.

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    • Dreyton, C. J., Knuckley, B., Jones, J. E., Lewallen, D. M., Thompson, P. R. Mechanistic studies of protein arginine deiminase 2: evidence for a substrate-assisted mechanism Biochemistry  2014 53:4426-4433  DOI:10.1021/bi500554b  PMID:24989433  PMCID:PMC4100781
    • Foyn, H., Jones, J. E., Lewallen, D., Narawane, R., Varhaug, J. E., Thompson, P. R., Arnesen, T. Design, synthesis, and kinetic characterization of protein N-terminal acetyltransferase inhibitors ACS Chemical Biology  2013 8:1121-1127  DOI:10.1021/cb400136s  PMID:23557624
    • Jones, J. E., Slack, J. L., Fang, P. F., Zhang, X. S., Subramanian, V., Causey, C. P., Coonrod, S. A., Guo, M., Thompson, P. R. Synthesis and screening of a haloacetamidine containing library to identify PAD4 selective inhibitors ACS Chemical Biology  2012 7:160-165  DOI:10.1021/cb200258q  PMID:22004374  PMCID:PMC3262960
    • Obianyo, O., Causey, C. P., Jones, J. E., Thompson, P. R. Activity-based protein profiling of protein arginine methyltransferase 1 ACS Chemical Biology  2011 6:1127-1135  DOI:10.1021/cb2001473  PMID:21838253  PMCID:PMC3199286
    • Chumanevich, A. A., Causey, C. P., Knuckley, B. A., Jones, J. E., Poudyal, D., Chumanevich, A. P., Davis, T., Matesic, L. E., Thompson, P. R., Hofseth, L. J. Suppression of colitis in mice by cl-amidine: A novel peptidylarginine deiminase inhibitor American Journal of Physiology-Gastrointestinal and Liver Physiology  2011 300:G929-G938  DOI:10.1152/ajpgi.00435.2010  PMID:21415415  PMCID:PMC3119113
    • Causey, C. P., Jones, J. E., Slack, J. L., Kamei, D., Jones, L. E., Subramanian, V., Knuckley, B., Ebrahimi, P., Chumanevich, A. A., Luo, Y., Hashimoto, H., Sato, M., et al. The development of n-alpha-(2-carboxyl)benzoyl-n(5)-(2-fluoro-1-iminoethyl)-l-ornithine amide (o-f-amidine) and n-alpha-(2-carboxyl)benzoyl-n(5)-(2-chloro-1-iminoethyl)-l-ornithine amide (o-cl-amidine) as second generation protein arginine deiminase (pad) inhibitors Journal of Medicinal Chemistry  2011 54:6919-6935  DOI:10.1021/jm2008985  PMID:21882827  PMCID:PMC3196593
    • Jones, J. E., Dreyton, C. J., Flick, H., Causey, C. P., Thompson, P. R. Mechanistic studies of agmatine deiminase from multiple bacterial species Biochemistry  2010 49:9413-9423  DOI:10.1021/bi101405y  PMID:20939536  PMCID:PMC2964429
    • Knuckley, B., Causey, C. P., Jones, J. E., Bhatia, M., Dreyton, C. J., Osborne, T. C., Takahara, H., Thompson, P. R. Substrate specificity and kinetic studies of pads 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3 Biochemistry  2010 49:4852-4863  DOI:10.1021/bi100363t  PMID:20469888  PMCID:PMC2884139
    • Obianyo, O., Causey, C. P., Osborne, T. C., Jones, J. E., Lee, Y. H., Stallcup, M. R., Thompson, P. R. A chloroacetamidine-based inactivator of protein arginine methyltransferase 1: Design, synthesis, and in vitro and in vivo evaluation ChemBioChem  2010 11:1219-1223  DOI:10.1002/cbic.201000209  PMID:20480486  PMCID:PMC3060404
    • Jones, J. E., Causey, C. P., Lovelace, L., Knuckley, B., Flick, H., Lebioda, L., Thompson, P. R. Characterization and inactivation of an agmatine deiminase from helicobacter pylori Bioorganic Chemistry  2010 38:62-73  DOI:10.1016/j.bioorg.2009.11.004  PMID:20036411  PMCID:PMC2823940
    • Knuckley, B., Jones, J. E., Bachovchin, D. A., Slack, J., Causey, C. P., Brown, S. J., Rosen, H., Cravatt, B. F., Thompson, P. R. A fluopol-ABPP HTS assay to identify PAD inhibitors Chemical Communications  2010 46:7175-7177  DOI:10.1039/c0cc02634d  PMID:20740228  PMCID:PMC2943038
    • Jones, J. E., Causey, C. P., Knuckley, B., Slack-Noyes, J. L., Thompson, P. R. Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential Current Opinion in Drug Discovery & Development  2009 12:616-627  PMID:19736621  PMCID:PMC3771078
    • Pollard, K. M., Jones, J. E., Tan, E. M., Theofilopoulos, A. N., Dixon, F. J., Rubin, R. L. Polynucleotide specificities of murine monoclonal anti-DNA antibodies Clinical Immunology and Immunopathology  1986 40:197-208  DOI:10.1016/0090-1229(86)90022-x  PMID:3487402
  • report

    • Dreyton, C. J., Jones, J. E., Knuckley, B. A., Subramanian, V., Anderson, E. D., Brown, S. J., Fernandez-Vega, V., Eberhart, C., Spicer, T., Zuhl, A. M., Ferguson, J., Speers, A. E., et al. Optimization and characterization of a pan protein arginine deiminase (PAD) inhibitor Probe Reports from the NIH Molecular Libraries Program. 2010  PMID:23833800

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