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Nuclear pore complexes: Dynamics in unexpected places

Academic Article
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Overview

authors

  • Lyman, S. K.
  • Gerace, Larry

publication date

  • July 2001

journal

  • Journal of Cell Biology  Journal

abstract

  • In vivo studies on the dynamics of the nuclear pore complex (NPC) in yeast suggested that NPCs are highly mobile in the nuclear envelope. However, new evidence indicates that in mammalian cells NPCs are stably attached to a flexible lamina framework, but a peripheral component can exchange rapidly with an intranuclear pool.

subject areas

  • Active Transport, Cell Nucleus
  • Animals
  • Basement Membrane
  • Cell Nucleus
  • Models, Biological
  • Nuclear Envelope
  • Nuclear Pore
  • Nuclear Pore Complex Proteins
  • Nuclear Proteins
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Identity

PubMed Central ID

  • PMC2196851

International Standard Serial Number (ISSN)

  • 0021-9525

Digital Object Identifier (DOI)

  • 10.1083/jcb.200106071

PubMed ID

  • 11448985
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Additional Document Info

start page

  • 17

end page

  • 20

volume

  • 154

issue

  • 1

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