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Elevated platelet-associated igg in thrombotic thrombocytopenic purpura

Academic Article
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Overview

authors

  • Morrison, J.
  • Mc Millan, Robert

publication date

  • 1977

journal

  • JAMA-Journal of the American Medical Association  Journal

abstract

  • A 41-year--old woman with thrombotic thrombocytopenic purpura (TTP) was treated with prednisone and splenectomy with complete recovery from her illness. Analysis of the patient's platelets for immunoglobulins showed abnormally elevated levels in the range of those seen in thrombocytopenic patients with systemic lupus erythematosus, immune vasculitis, and infectious mononucleosis. This finding is consistent with the concept that the immune system may play a role in the pathogenesis of TTP.

subject areas

  • Adult
  • Blood Platelets
  • Female
  • Humans
  • Immunoglobulin G
  • Prednisone
  • Purpura, Thrombotic Thrombocytopenic
  • Splenectomy
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Identity

International Standard Serial Number (ISSN)

  • 0098-7484

Digital Object Identifier (DOI)

  • 10.1001/jama.238.18.1944

PubMed ID

  • 578556
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Additional Document Info

start page

  • 1944

end page

  • 1945

volume

  • 238

issue

  • 18

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