recent publications

• academic article

  • Cohen, A., Soleiman, M. T., Talia, R., Koob, G. F., George, O., Mandyam, C. D. Extended access nicotine self-administration with periodic deprivation increases immature neurons in the hippocampus Psychopharmacology  2015 232:453-463  DOI:10.1007/s00213-014-3685-0  PMID:25059540  PMCID:PMC4297709
  • Cohen, A., Treweek, J., Edwards, S., Leao, R. M., Schulteis, G., Koob, G. F., George, O. Extended access to nicotine leads to a CRF1 receptor dependent increase in anxiety-like behavior and hyperalgesia in rats Addiction Biology  2015 20:56-68  DOI:10.1111/adb.12077  PMID:23869743  PMCID:PMC3859819
  • Rock, E. M., Limebeer, C. L., Ward, J. M., Cohen, A., Grove, K., Niphakis, M. J., Cravatt, B. F., Parker, L. A. Interference with acute nausea and anticipatory nausea in rats by fatty acid amide hydrolase (FAAH) inhibition through a PPARα and CB1 receptor mechanism, respectively: a double dissociation Psychopharmacology  2015 232:3841-3848  DOI:10.1007/s00213-015-4050-7  PMID:26297326
  • Koob, G. F., Buck, C. L., Cohen, A., Edwards, S., Park, P. E., Schlosburg, J. E., Schmeichel, B., Vendruscolo, L. F., Wade, C. L., Whitfield, T. W., George, O. Addiction as a stress surfeit disorder Neuropharmacology  2014 76:370-382  DOI:10.1016/j.neuropharm2013.05.024  PMID:23747571  PMCID:PMC3830720
  • Grieder, T. E., Herman, M. A., Contet, C., Tan, L. A., Vargas-Perez, H., Cohen, A., Chwalek, M., Maal-Bared, G., Freiling, J., Schlosburg, J. E., Clarke, L., Crawford, E., et al. VTA CRF neurons mediate the aversive effects of nicotine withdrawal and promote intake escalation Nature Neuroscience  2014 17:1751-1758  DOI:10.1038/nn.3872  PMID:25402857  PMCID:PMC4241147
  • Cohen, A., Whitfield, T. W., Kreifeldt, M., Koebel, P., Kieffer, B. L., Contet, C., George, O., Koob, G. F. Virus-mediated shRNA knockdown of prodynorphin in the rat nucleus accumbens attenuates depression-like behavior and cocaine locomotor sensitization PLoS One  2014 9:e97216  DOI:10.1371/journal.pone.0097216  PMID:24816773  PMCID:PMC4016270
  • Cohen, A., George, O. Animal models of nicotine exposure: relevance to second-hand smoking, electronic cigarette use, and compulsive smoking Frontiers in Psychiatry  2013 4:41  DOI:10.3389/fpsyt.2013.00041  PMID:23761766  PMCID:PMC3671664
  • Goeders, N. E., Cohen, A., Fox, B. S., Azar, M. R., George, O., Koob, G. F. Effects of the combination of metyrapone and oxazepam on intravenous nicotine self-administration in rats Psychopharmacology  2012 223:17-25  DOI:10.1007/s00213-012-2682-4  PMID:22418732  PMCID:PMC3464482
  • Cohen, A., Koob, G. F., George, O. Robust escalation of nicotine intake with extended access to nicotine self-administration and intermittent periods of abstinence Neuropsychopharmacology  2012 37:2153-2160  DOI:10.1038/npp.2012.67  PMID:22549121  PMCID:PMC3398720
  • Fallin, D., Cohen, A., Essioux, L., Chumakov, I., Blumenfeld, M., Cohen, D., Schork, N. J. Genetic analysis of case/control data using estimated haplotype frequencies: Application to apoe locus variation and alzheimer's disease Genome Research  2001 11:143-151  DOI:10.1101/gr.148401  PMID:11156623
  • Topol, E. J., Califf, R., Granger, C., VandeWerf, F., Aylward, P., Simes, J., Col, J., Armstrong, P., Vahanian, A., Neuhaus, K., Rutsch, W., Ardissino, D., et al. A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes New England Journal of Medicine  1996 335:775-782  DOI:10.1056/NEJM199609123351103  PMID:8778585