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Pan-Src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells

Academic Article
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Overview

related to degree

  • Bollong, Michael Joseph, Ph.D. in Chemical Biology, Scripps Research 2010 - 2016
  • Lyssiotis, Costas A, Ph.D. in Chemical Biology, Scripps Research 2005 - 2010

authors

  • Staerk, J.
  • Lyssiotis, Costas A
  • Medeiro, L. A.
  • Bollong, Michael Joseph
  • Foreman, R. K.
  • Zhu, S.
  • Garcia, M.
  • Gao, Q.
  • Bouchez, L. C.
  • Lairson, Luke
  • Charette, B. D.
  • Supekova, L.
  • Janes, J.
  • Brinker, A.
  • Cho, C. Y.
  • Jaenisch, R.
  • Schultz, Peter

publication date

  • 2011

journal

  • Angewandte Chemie-International Edition  Journal

subject areas

  • Animals
  • Cellular Reprogramming
  • Dasatinib
  • Doxycycline
  • Fibroblasts
  • High-Throughput Screening Assays
  • Induced Pluripotent Stem Cells
  • Mice
  • Protein Kinase Inhibitors
  • Pyrimidines
  • SOXB1 Transcription Factors
  • Thiazoles
  • Transforming Growth Factor beta
  • src-Family Kinases
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Research

keywords

  • Sox2
  • Src family kinases
  • cell-based screening
  • dasatinib
  • iPS cells
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Identity

PubMed Central ID

  • PMC3409461

International Standard Serial Number (ISSN)

  • 1433-7851

Digital Object Identifier (DOI)

  • 10.1002/anie.201101042

PubMed ID

  • 21547985
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Additional Document Info

start page

  • 5733

end page

  • 5735

volume

  • 50

issue

  • 25

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