recent publications

• academic article

  • Schreiber, R. E., Prossnitz, E. R., Ye, R. D., Cochrane, C. G., Jesaitis, A. J., Bokoch, G. M. Reconstitution of recombinant N-formyl chemotactic peptide receptor with G protein Journal of Leukocyte Biology  1993 53:470-474  PMID:8482927
  • Parkos, C. A., Allen, R. A., Cochrane, C. G., Jesaitis, A. J. The quaternary structure of the plasma membrane b-type cytochrome of human granulocytes Biochimica et Biophysica Acta  1988 932:71-83  DOI:10.1016/0005-2728(88)90140-5  PMID:3337799
  • Schmitt, M., Painter, R. G., Vontscharner, V., Sklar, L. A., Jesaitis, A. J., Fayle, D. H., Cochrane, C. G. Monoclonal antibody NMS-1 increases N-formyl chemotactic peptide-mediated oxidative burst generation in human neutrophils Journal of Immunology  1987 139:4178-4185  PMID:3693902
  • Allen, R. A., Jesaitis, A. J., Cochrane, C. G. Photoaffinity labelling of N-formyl peptide receptors Pharmacology & Therapeutics  1987 33:333-348  DOI:10.1016/0163-7258(87)90070-2  PMID:3310037
  • Parkos, C. A., Allen, R. A., Cochrane, C. G., Jesaitis, A. J. Purified cytochrome b from human granulocyte plasma membrane is comprised of two polypeptides with relative molecular weights of 91,000 and 22,000 Journal of Clinical Investigation  1987 80:732-742  DOI:10.1172/jci113128  PMID:3305576  PMCID:PMC442297
  • Allen, R. A., Jesaitis, A. J., Sklar, L. A., Cochrane, C. G., Painter, R. G. Physicochemical properties of the N-formyl peptide receptor on human neutrophils Journal of Biological Chemistry  1986 261:1854-1857  PMID:3944114
  • Jesaitis, A. J., Tolley, J. O., Painter, R. G., Sklar, L. A., Cochrane, C. G. Membrane-cytoskeleton interactions and the regulation of chemotactic peptide-induced activation of human granulocytes: the effects of dihydrocytochalasin B Journal of Cellular Biochemistry  1985 27:241-253  DOI:10.1002/jcb.240270306  PMID:3838753
  • Ross, M. I., Deems, R. A., Jesaitis, A. J., Dennis, E. A., Ulevitch, R. J. Phospholipase activities of the p388d1 macrophage-like cell-line Archives of Biochemistry and Biophysics  1985 238:247-258  DOI:10.1016/0003-9861(85)90162-6  PMID:3985620
  • Parkos, C. A., Cochrane, C. G., Schmitt, M., Jesaitis, A. J. Regulation of the oxidative response of human granulocytes to chemoattractants. No evidence for stimulated traffic of redox enzymes between endo and plasma membranes Journal of Biological Chemistry  1985 260:6541-6547  PMID:2987226
  • Sklar, L. A., Hyslop, P. A., Oades, Z. G., Omann, G. M., Jesaitis, A. J., Painter, R. G., Cochrane, C. G. Signal transduction and ligand-receptor dynamics in the human neutrophil. Transient responses and occupancy-response relations at the formyl peptide receptor Journal of Biological Chemistry  1985 260:1461-1467  PMID:2995337
  • Painter, R. G., Sklar, L. A., Jesaitis, A. J., Schmitt, M., Cochrane, C. G. Activation of neutrophils by N-formyl chemotactic peptides Federation Proceedings  1984 43:2737-2742  PMID:6088297
  • Hyslop, P. A., Oades, Z. G., Jesaitis, A. J., Painter, R. G., Cochrane, C. G., Sklar, L. A. Evidence for N-formyl chemotactic peptide-stimulated GTPase activity in human neutrophil homogenates FEBS Letters  1984 166:165-169  DOI:10.1016/0014-5793(84)80065-4  PMID:6141069
  • Jesaitis, A. J., Naemura, J. R., Sklar, L. A., Cochrane, C. G., Painter, R. G. Rapid modulation of N-formyl chemotactic peptide receptors on the surface of human granulocytes: formation of high-affinity ligand-receptor complexes in transient association with cytoskeleton Journal of Cell Biology  1984 98:1378-1387  DOI:10.1083/jcb.98.4.1378  PMID:6325470  PMCID:PMC2113208
  • Sklar, L. A., Finney, D. A., Oades, Z. G., Jesaitis, A. J., Painter, R. G., Cochrane, C. G. The dynamics of ligand-receptor interactions. Real-time analyses of association, dissociation, and internalization of an N-formyl peptide and its receptors on the human neutrophil Journal of Biological Chemistry  1984 259:5661-5669  PMID:6715364
  • Schmitt, M., Painter, R. G., Jesaitis, A. J., Preissner, K., Sklar, L. A., Cochrane, C. G. Photoaffinity labeling of the N-formyl peptide receptor binding site of intact human polymorphonuclear leukocytes. A label suitable for following the fate of the receptor-ligand complex Journal of Biological Chemistry  1983 258:649-654  PMID:6294117
  • Jesaitis, A. J., Cochrane, C. G. Receptor-mediated endocytosis, host defense, and inflammation Laboratory Investigation  1983 48:117-119  PMID:6823095
  • Jesaitis, A. J., Naemura, J. R., Painter, R. G., Sklar, L. A., Cochrane, C. G. The fate of an N-formylated chemotactic peptide in stimulated human granulocytes. Subcellular fractionation studies Journal of Biological Chemistry  1983 258:1968-1977  PMID:6822545
  • Sklar, L. A., McNeil, V. M., Jesaitis, A. J., Painter, R. G., Cochrane, C. G. A continuous, spectroscopic analysis of the kinetics of elastase secretion by neutrophils. The dependence of secretion upon receptor occupancy Journal of Biological Chemistry  1982 257:5471-5475  PMID:6917847
  • Jesaitis, A. J., Naemura, J. R., Painter, R. G., Sklar, L. A., Cochrane, C. G. Intracellular localization of N-formyl chemotactic receptor and Mg2+ dependent ATPase in human granulocytes Biochimica et Biophysica Acta  1982 719:556-568  DOI:10.1016/0304-4165(82)90246-x  PMID:6129903
  • Sklar, L. A., Jesaitis, A. J., Painter, R. G., Cochrane, C. G. Ligand/receptor internalization: a spectroscopic analysis and a comparison of ligand binding, cellular response, and internalization by human neutrophils Journal of Cellular Biochemistry  1982 20:193-202  DOI:10.1002/jcb.240200210  PMID:6302116
  • Painter, R. G., Schmitt, M., Jesaitis, A. J., Sklar, L. A., Preissner, K., Cochrane, C. G. Photoaffinity labeling of the N-formyl peptide receptor of human polymorphonuclear leukocytes Journal of Cellular Biochemistry  1982 20:203-214  DOI:10.1002/jcb.240200211  PMID:6302117
  • Jesaitis, A. J., Naemura, J. R., Painter, R. G., Schmitt, M., Sklar, L. A., Cochrane, C. G. The fate of the N-formyl-chemotactic peptide receptor in stimulated human granulocytes: subcellular fractionation studies Journal of Cellular Biochemistry  1982 20:177-191  DOI:10.1002/jcb.240200209  PMID:6302115
  • Sklar, L. A., Oades, Z. G., Jesaitis, A. J., Painter, R. G., Cochrane, C. G. Fluoresceinated chemotactic peptide and high-affinity anti-fluorescein antibody as a probe of the temporal characteristics of neutrophil stimulation Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences  1981 78:7540-7544  DOI:10.1073/pnas.78.12.7540  PMID:7038681  PMCID:PMC349304
  • Sklar, L. A., Jesaitis, A. J., Painter, R. G., Cochrane, C. G. The kinetics of neutrophil activation. The response to chemotactic peptides depends upon whether ligand-receptor interaction is rate-limiting Journal of Biological Chemistry  1981 256:9909-9914  PMID:6268635