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B cell memory and the long-lived plasma cell

Academic Article
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Overview

authors

  • McHeyzer-Williams, Michael G.
  • Ahmed, R.

publication date

  • April 1999

journal

  • Current Opinion in Immunology  Journal

abstract

  • The germinal center reaction is pivotal to the induction of B cell memory. The signals that regulate this complex microenvironment, with their cellular and molecular consequences, underpin long-term protective immunity. Recent studies have identified many key regulators of the germinal center cycle and have revealed an array of cellular outcomes that further define the memory B cell compartment.

subject areas

  • Animals
  • B-Lymphocytes
  • Germinal Center
  • Humans
  • Immunoglobulin G
  • Immunologic Memory
  • Plasma Cells
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Identity

International Standard Serial Number (ISSN)

  • 0952-7915

Digital Object Identifier (DOI)

  • 10.1016/s0952-7915(99)80029-6

PubMed ID

  • 10322151
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Additional Document Info

start page

  • 172

end page

  • 179

volume

  • 11

issue

  • 2

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