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Pilot study of the antiplatelet effect of increased clopidogrel maintenance dosing and its relationship to cyp2c19 genotype in patients with high on-treatment reactivity

Academic Article
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Overview

authors

  • Barker, C. M.
  • Murray, Sarah
  • Teirstein, P. S.
  • Kandzari, D. E.
  • Topol, Eric
  • Price, M. J.

publication date

  • October 2010

journal

  • JACC-Cardiovascular Interventions  Journal

subject areas

  • Aged
  • Aryl Hydrocarbon Hydroxylases
  • Body Mass Index
  • California
  • Chi-Square Distribution
  • Coronary Artery Disease
  • Cytochrome P-450 CYP2C19
  • Female
  • Genotype
  • Humans
  • Logistic Models
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Phenotype
  • Pilot Projects
  • Platelet Aggregation
  • Platelet Aggregation Inhibitors
  • Platelet Function Tests
  • Polymorphism, Genetic
  • Predictive Value of Tests
  • Receptors, Purinergic P2Y12
  • Risk Assessment
  • Risk Factors
  • Ticlopidine
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Research

keywords

  • CYP2C19
  • clopidogrel
  • platelet
  • thienopyridine
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Identity

International Standard Serial Number (ISSN)

  • 1936-8798

Digital Object Identifier (DOI)

  • 10.1016/j.jcin.2010.07.012

PubMed ID

  • 20965456
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Additional Document Info

start page

  • 1001

end page

  • 1007

volume

  • 3

issue

  • 10

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