recent publications
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academic article
- Savas, U., Machemer, D. E. W., Hsu, M. H., Gaynor, P., Lasker, J. M., Tukey, R. H., Johnson, E. F. Opposing roles of peroxisome proliferator-activated receptor alpha and growth hormone in the regulation of CYP4A11 expression in a transgenic mouse model Journal of Biological Chemistry 2009 284:16541-16552 DOI:10.1074/jbc.M902074200 PMID:19366684 PMCID:PMC2713544
- Guengerich, F. P., Parikh, A., Johnson, E. F., Richardson, T. H., von Wachenfeldt, C., Cosme, J., Jung, F., Strassburg, C. P., Manns, M. P., Tukey, R. H., Pritchard, M., Fournel-Gigleux, S., et al. Heterologous expression of human drug-metabolizing enzymes Drug Metabolism and Disposition 1997 25:1234-1241 PMID:9351898
- Philipp, T., Durazzo, M., Trautwein, C., Alex, B., Straub, P., Lamb, J. G., Johnson, E. F., Tukey, R. H., Manns, M. P. Recognition of uridine diphosphate glucuronosyl transferases by LKM-3 antibodies in chronic hepatitis D Lancet 1994 344:578-581 DOI:10.1016/s0140-6736(94)91966-6 PMID:7914961
- Hapgood, J., Cuthill, S., Soderkvist, P., Wilhelmsson, A., Pongratz, I., Tukey, R. H., Johnson, E. F., Gustafsson, J. A., Poellinger, L. Liver-cells contain constitutive DNase I-hypersensitive sites at the xenobiotic response element-1 and element-2 (XRE1 and XRE2) of the rat cytochrome-P-450IA1 gene and a constitutive, nuclear XRE-bindingfactor that is distinct from the dioxin receptor Molecular and Cellular Biology 1991 11:4314-4323 PMID:1652054 PMCID:PMC361292
- Johnson, E. F., Kronbach, T., Muerhoff, A. S., Griffin, K. J., Pendurthi, U. R., Tukey, R. H. Multiple forms of rabbit cytochrome P450: comparison of chemical physical, immunological and biocatalytic properties NATO ASI Series, Series A Life Sciences 1991 202:23-54
- Pendurthi, U. R., Lamb, J. G., Nguyen, N., Johnson, E. F., Tukey, R. H. Characterization of the CYP2C5 gene in 21L III/J rabbits. Allelic variation affects the expression of P450IIC5 Journal of Biological Chemistry 1990 265:14662-14668 PMID:2387874
- Manns, M. P., Griffin, K. J., Quattrochi, L. C., Sacher, M., Thaler, H., Tukey, R. H., Johnson, E. F. Identification of cytochrome P450IA2 as a human autoantigen Archives of Biochemistry and Biophysics 1990 280:229-232 DOI:10.1016/0003-9861(90)90541-6 PMID:2353823
- Potenza, C. L., Pendurthi, U. R., Strom, D. K., Tukey, R. H., Griffin, K. J., Schwab, G. E., Johnson, E. F. Regulation of the rabbit cytochrome-P-450 3C gene - age-dependent expression and transcriptional activation by rifampicin Journal of Biological Chemistry 1989 264:16222-16228 PMID:2777787
- Johnson, E. F., Finlayson, M., Hujsak, C. M., Pendurthi, U. R., Tukey, R. H. Genetic contributions to the variation among rabbits of liver microsomal deoxycorticosterone synthesis Archives of Biochemistry and Biophysics 1989 273:273-280 DOI:10.1016/0003-9861(89)90484-0 PMID:2570549
- Johnson, E. F., Barnes, H. J., Griffin, K. J., Okino, S., Tukey, R. H. Characterization of a second gene product related to rabbit cytochrome P-450 1 Journal of Biological Chemistry 1987 262:5918-5923 PMID:3032948
- Johnson, E. F., Finlayson, M., Raucy, J., Barnes, H., Schwab, G. E., Griffin, K. J., Tukey, R. H. Intraspecies individuality for the metabolism of steroids Xenobiotica 1987 17:275-285 PMID:3577205
- Okino, S. T., Quattrochi, L. C., Barnes, H. J., Osanto, S., Griffin, K. J., Johnson, E. F., Tukey, R. H. Cloning and characterization of cDNAs encoding 2,3,7,8-tetrachlorodibenzo-para-dioxin-inducible rabbit messenger-RNAs for cytochrome-P-450 isozyme-4 and isozyme-6 Proceedings of the National Academy of Sciences of the United States of America 1985 82:5310-5314 DOI:10.1073/pnas.82.16.5310 PMID:2991917
- Tukey, R. H., Okino, S., Barnes, H., Griffin, K. J., Johnson, E. F. Multiple gene-like sequences related to the rabbit hepatic progesterone 21-hydroxylase cytochrome P-450 1 Journal of Biological Chemistry 1985 260:3347-3354 PMID:3902818