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Calcitonin gene-related peptide (CGRP) levels and alcohol

Academic Article
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Overview

authors

  • Ehlers, Cindy
  • Somes, C.
  • Li, T. K.
  • Lumeng, L.
  • Hwang, B. H.
  • Jimenez, P.
  • Mathe, A. A.

publication date

  • September 1999

journal

  • International Journal of Neuropsychopharmacology  Journal

abstract

  • The present paper is a continuation of studies for establishing the optimal schedule of blood-donor immunization for obtaining of plasma suitable for production of anti-RhD immunoglobulin. After 3 years of observation of 12 immunized subjects it was found that stimulation of the secondary immune response should be done with small doses (0.5-1 ml) of blood injected intravenously at long time intervals, that is 1-3 times in a year. This method leads to a high and long-term rise in the titre of antibodies exceeding in all cases the value of 1/128 in indirect antiglobulin test, that is suitable for production of the preparation Gamma anti-D 150.

subject areas

  • Antibody Formation
  • Blood Donors
  • Humans
  • Immunization, Secondary
  • Rh-Hr Blood-Group System
  • Time Factors
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Research

keywords

  • alcohol-preferring rats
  • alcoholism
  • amygdala
  • calcitonin gene-related peptide (CGRP)
  • chronic ethanol exposure
  • frontal cortex
  • hippocampus
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Identity

International Standard Serial Number (ISSN)

  • 1461-1457

Digital Object Identifier (DOI)

  • 10.1017/s1461145799001558

PubMed ID

  • 112819
  • 11281986
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Additional Document Info

start page

  • 173

end page

  • 179

volume

  • 2

issue

  • 3

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