Calcitonin gene-related peptide (CGRP) levels and alcohol

Academic Article

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• Research
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Overview

authors

• Ehlers, Cindy
• Somes, C.
• Li, T. K.
• Lumeng, L.
• Hwang, B. H.
• Jimenez, P.
• Mathe, A. A.

publication date

• 1999

journal

• International Journal of Neuropsychopharmacology  Journal

abstract

• The present paper is a continuation of studies for establishing the optimal schedule of blood-donor immunization for obtaining of plasma suitable for production of anti-RhD immunoglobulin. After 3 years of observation of 12 immunized subjects it was found that stimulation of the secondary immune response should be done with small doses (0.5-1 ml) of blood injected intravenously at long time intervals, that is 1-3 times in a year. This method leads to a high and long-term rise in the titre of antibodies exceeding in all cases the value of 1/128 in indirect antiglobulin test, that is suitable for production of the preparation Gamma anti-D 150.

subject areas

• Antibody Formation
• Blood Donors
• Humans
• Immunization, Secondary
• Rh-Hr Blood-Group System
• Time Factors

Research

keywords

• alcohol-preferring rats
• alcoholism
• amygdala
• calcitonin gene-related peptide (CGRP)
• chronic ethanol exposure
• frontal cortex
• hippocampus

Identity

International Standard Serial Number (ISSN)

• 1461-1457

Digital Object Identifier (DOI)

• 10.1017/s1461145799001558

PubMed ID

• 112819
• 11281986

Additional Document Info

start page

• 173

end page

• 179

volume

• 2

issue

• 3