recent publications

• academic article

  • Menichelli, E., Edgcomb, S. P., Recht, M. I., Williamson, J. R. The structure of Aquifex aeolicus ribosomal protein S8 reveals a unique subdomain that contributes to an extremely tight association with 16S rRNA Journal of Molecular Biology  2012 415:489-502  DOI:10.1016/j.jmb.2011.10.046  PMID:22079365  PMCID:PMC3259246
  • Edgcomb, S. P., Carmel, A. B., Naji, S., Ambrus-Aikelin, G., Reyes, J. R., Saphire, A. C. S., Gerace, L., Williamson, J. R. DDX1 is an RNA-dependent ATPase involved in HIV-1 Rev function and virus replication Journal of Molecular Biology  2012 415:61-74  DOI:10.1016/j.jmb.2011.10.032  PMID:22051512  PMCID:PMC3249508
  • Robertson-Anderson, R. M., Wang, J., Edgcomb, S. P., Carmel, A. B., Williamson, J. R., Millar, D. P. Single-molecule studies reveal that dead box protein DDX1 promotes oligomerization of HIV-1 Rev on the Rev response element Journal of Molecular Biology  2011 410:959-971  DOI:10.1016/j.jmb.2011.04.026  PMID:21763499  PMCID:PMC3140434
  • Edgcomb, S. P., Aschrafi, A., Kompfner, E., Williamson, J. R., Gerace, L., Hennig, M. Protein structure and oligomerization are important for the formation of export-competent HIV-1 Rev-RRE complexes Protein Science  2008 17:420-430  DOI:10.1110/ps.073246608  PMID:18218716  PMCID:PMC2248316