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Structural basis for the binding of an anti-cytochrome c antibody to its antigen: Crystal structures of FabE8 cytochrome c complex to 1.8 Å resolution and FabE8 to 2.26 Å resolution

Academic Article
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Overview

authors

  • Mylvaganam, S. E.
  • Paterson, Y.
  • Getzoff, Elizabeth

publication date

  • August 1998

journal

  • Journal of Molecular Biology  Journal

subject areas

  • Animals
  • Antibodies, Monoclonal
  • Antigen-Antibody Reactions
  • Binding Sites, Antibody
  • Crystallography, X-Ray
  • Cytochrome c Group
  • Epitope Mapping
  • Epitopes
  • Immunoglobulin Fab Fragments
  • Mice
  • Models, Molecular
  • Protein Conformation
  • Protein Structure, Secondary
  • Water
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Research

keywords

  • Fab complex
  • X-ray structures
  • antibody-antigen interactions
  • conformational change
  • cytochrome c
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Identity

International Standard Serial Number (ISSN)

  • 0022-2836

Digital Object Identifier (DOI)

  • 10.1006/jmbi.1998.1942

PubMed ID

  • 9698550
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Additional Document Info

start page

  • 301

end page

  • 322

volume

  • 281

issue

  • 2

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