Enzyme-catalyzed oligosaccharide synthesis

Academic Article

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Overview

authors

• Ichikawa, Y.
• Look, G. C.
• Wong, Chi-Huey

publication date

• May 1992

journal

• Analytical Biochemistry  Journal

abstract

• Cell-surface carbohydrates and their conjugates are involved in many types of molecular recognition. This review describes recent developments in enzyme-catalyzed oligosaccharide synthesis, with particular focus on glycosyltransferase and glycosidase reactions. With the increasing availability of glycosyltransferases via recombinant DNA technology, glycosyltransferase-catalyzed glycosylation with in situ regeneration of sugar nucleotides appears to be the most effective method for large-scale stereocontrolled oligosaccharide synthesis.

subject areas

• Carbohydrate Sequence
• Glycoside Hydrolases
• Glycosyltransferases
• Molecular Sequence Data
• Oligosaccharides

Identity

International Standard Serial Number (ISSN)

• 0003-2697

Digital Object Identifier (DOI)

• 10.1016/0003-2697(92)90099-s

PubMed ID

• 1519746

Additional Document Info

start page

• 215

end page

• 238

volume

• 202

issue

• 2