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Enzyme-catalyzed oligosaccharide synthesis

Academic Article
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Overview

authors

  • Ichikawa, Y.
  • Look, G. C.
  • Wong, Chi-Huey

publication date

  • May 1992

journal

  • Analytical Biochemistry  Journal

abstract

  • Cell-surface carbohydrates and their conjugates are involved in many types of molecular recognition. This review describes recent developments in enzyme-catalyzed oligosaccharide synthesis, with particular focus on glycosyltransferase and glycosidase reactions. With the increasing availability of glycosyltransferases via recombinant DNA technology, glycosyltransferase-catalyzed glycosylation with in situ regeneration of sugar nucleotides appears to be the most effective method for large-scale stereocontrolled oligosaccharide synthesis.

subject areas

  • Carbohydrate Sequence
  • Glycoside Hydrolases
  • Glycosyltransferases
  • Molecular Sequence Data
  • Oligosaccharides
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Identity

International Standard Serial Number (ISSN)

  • 0003-2697

Digital Object Identifier (DOI)

  • 10.1016/0003-2697(92)90099-s

PubMed ID

  • 1519746
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Additional Document Info

start page

  • 215

end page

  • 238

volume

  • 202

issue

  • 2

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