recent publications
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academic article
- Avalos, A. M., Kirak, O., Oelkers, J. M., Pils, M. C., Kim, Y. M., Ottinger, M., Jaenisch, R., Ploegh, H. L., Brinkmann, M. M. Cell-specific TLR9 trafficking in primary APCs of transgenic TLR9-GFP mice Journal of Immunology 2013 190:695-702 DOI:10.4049/jimmunol.1202342 PMID:23241879 PMCID:PMC3539690
- Ryan, S. D., Dolatabadi, N., Chan, S. F., Zhang, X., Akhtar, M. W., Parker, J., Soldner, F., Sunico, C. R., Nagar, S., Talantova, M., Lee, B., Lopez, K., et al. Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1 alpha transcription Cell 2013 155:1351-1364 DOI:10.1016/j.cell.2013.11.009 PMID:24290359 PMCID:PMC4028128
- Sehrawat, S., Kirak, O., Koenig, P. A., Isaacson, M. K., Marques, S., Bozkurt, G., Simas, J. P., Jaenisch, R., Ploegh, H. L. CD8(+) T cells from mice transnuclear for a TCR that recognizes a single H-2K(b)-restricted MHV68 epitope derived from gB-ORF8 help control infection Cell Reports 2012 1:461-471 DOI:10.1016/j.celrep.2012.03.009 PMID:22832272 PMCID:PMC3406328
- Zheng, G. X. Y., Ravi, A., Calabrese, J. M., Medeiros, L. A., Kirak, O., Dennis, L. M., Jaenisch, R., Burge, C. B., Sharp, P. A. A latent pro-survival function for the mir-290-295 cluster in mouse embryonic stem cells PLoS Genetics 2011 7:e1002054 DOI:10.1371/journal.pgen.1002054 PMID:21573140 PMCID:PMC3088722
- Medeiros, L. A., Dennis, L. M., Gill, M. E., Houbaviy, H., Markoulaki, S., Fu, D. D., White, A. C., Kirak, O., Sharp, P. A., Page, D. C., Jaenisch, R. Mir-290-295 deficiency in mice results in partially penetrant embryonic lethality and germ cell defects Proceedings of the National Academy of Sciences of the United States of America 2011 108:14163-14168 DOI:10.1073/pnas.1111241108 PMID:21844366 PMCID:PMC3161528
- Staerk, J., Lyssiotis, C. A., Medeiro, L. A., Bollong, M., Foreman, R. K., Zhu, S. T., Garcia, M., Gao, Q., Bouchez, L. C., Lairson, L. L., Charette, B. D., Supekova, L. Pan-Src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells Angewandte Chemie-International Edition 2011 50:5733-5735 DOI:10.1002/anie.201101042 PMID:21547985 PMCID:PMC3409461
- Kim, J., Lengner, C. J., Kirak, O., Hanna, J., Cassady, J. P., Lodato, M. A., Wu, S., Faddah, D. A., Steine, E. J., Gao, Q., Fu, D. D., Dawlaty, M., et al. Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors Stem Cells 2011 29:992-1000 DOI:10.1002/stem.641 PMID:21563275 PMCID:PMC3409465
- Kirak, O., Frickel, E. M., Grotenbreg, G. M., Suh, H., Jaenisch, R., Ploegh, H. L. Transnuclear mice with pre-defined T cell receptor specificities against Toxoplasma gondii obtained via SCNT Journal of Visualized Experiments : JoVE 2010 DOI:10.3791/2168 PMID:20972401 PMCID:PMC3157875
- Kirak, O., Frickel, E. M., Grotenbreg, G. M., Suh, H., Jaenisch, R., Ploegh, H. L. Transnuclear mice with predefined T cell receptor specificities against Toxoplasma gondii obtained via SCNT Science 2010 328:243-248 DOI:10.1126/science.1178590 PMID:20378817 PMCID:PMC2940321
- Skelley, A. M., Kirak, O., Suh, H., Jaenisch, R., Voldman, J. Microfluidic control of cell pairing and fusion Nature Methods 2009 6:147-152 DOI:10.1038/nmeth.1290 PMID:19122668 PMCID:PMC3251011
- Lyssiotis, C. A., Foreman, R. K., Staerk, J., Garcia, M., Mathur, D., Markoulaki, S., Hanna, J., Lairson, L. L., Charette, B. D., Bouchez, L. C., Bollong, M., Kunick, C., et al. Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4 Proceedings of the National Academy of Sciences of the United States of America 2009 106:8912-8917 DOI:10.1073/pnas.0903860106 PMID:19447925 PMCID:PMC2690053
- Kim, K., Ng, K., Rugg-Gunn, P. J., Shieh, J. H., Kirak, O., Jaenisch, R., Wakayama, T., Moore, M. A., Pedersen, R. A., Daley, G. Q. Recombination signatures distinguish embryonic stem cells derived by parthenogenesis and somatic cell nuclear transfer Cell Stem Cell 2007 1:346-352 DOI:10.1016/j.stem.2007.07.001 PMID:18371368
- Eggan, E., Baldwin, K., Tackett, M., Osborne, J., Gogos, J., Chess, A., Axel, R., Jaenisch, R. Mice cloned from olfactory sensory neurons Nature 2004 428:44-49 DOI:10.1038/nature02375 PMID:14990966
- Jaenisch, R., Hochedlinger, K., Blelloch, R., Yamada, Y., Baldwin, K., Eggan, K. Nuclear cloning, epigenetic reprogramming, and cellular differentiation Cold Spring Harbor Symposia on Quantitative Biology 2004 69:19-27 DOI:10.1101/sqb.2004.69.19 PMID:16117629
- Chun, J., Jaenisch, R. Clonal cell lines produced by infection of neocortical neuroblasts using multiple oncogenes transduced by retroviruses Molecular and Cellular Neuroscience 1996 7:304-321 DOI:10.1006/mcne.1996.0023 PMID:8793865
- Chun, J. J. M., Schatz, D. G., Oettinger, M. A., Jaenisch, R., Baltimore, D. The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system Cell 1991 64:189-200 DOI:10.1016/0092-8674(91)90220-s PMID:1986864