recent publications

• academic article

  • Chin, R. M., Fu, X., Pai, M. Y., Vergnes, L., Hwang, H., Deng, G., Diep, S., Lomenick, B., Meli, V. S., Monsalve, G. C., Hu, E., Whelan, S. A., et al. The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR Nature  2014 510:397-401  DOI:10.1038/nature13264  PMID:24828042  PMCID:PMC4263271
  • Gillespie, E. J., Ho, C. L. C., Balaji, K., Clemens, D. L., Deng, G., Wang, Y. E., Elsaesser, H. J., Tamilselvam, B., Gargi, A., Dixon, S. D., France, B., Chamberlain, B. T., et al. Selective inhibitor of endosomal trafficking pathways exploited by multiple toxins and viruses Proceedings of the National Academy of Sciences of the United States of America  2013 110:E4904-E4912  DOI:10.1073/pnas.1302334110  PMID:24191014  PMCID:PMC3864319
  • Deng, G., Curriden, S. A., Hu, G., Czekay, R. P., Loskutoff, D. J. Plasminogen activator inhibitor-1 regulates cell adhesion by binding to the somatomedin B domain of vitronectin Journal of Cellular Physiology  2001 189:23-33  DOI:10.1002/jcp.1133  PMID:11573201
  • Royle, G., Deng, G., Seiffert, D., Loskutoff, D. J. A method for defining binding sites involved in protein-protein interactions: analysis of the binding of plasminogen activator inhibitor 1 to the somatomedin domain of vitronectin Analytical Biochemistry  2001 296:245-253  DOI:10.1006/agio.2001.5316  PMID:11554720
  • Loskutoff, D. J., Curriden, S. A., Hu, G., Deng, G. Regulation of cell adhesion by PAI-1 APMIS  1999 107:54-61  PMID:10190280
  • Deng, G., Curriden, S. A., Wang, S., Rosenberg, S., Loskutoff, D. J. Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release? Journal of Cell Biology  1996 134:1563-1571  DOI:10.1083/jcb.134.6.1563  PMID:8830783  PMCID:PMC2120994
  • Deng, G., Royle, G., Wang, S., Crain, K., Loskutoff, D. J. Structural and functional analysis of the plasminogen activator inhibitor-1 binding motif in the somatomedin B domain of vitronectin Journal of Biological Chemistry  1996 271:12716-12723  PMID:8662688
  • Deng, G., Royle, G., Seiffert, D., Loskutoff, D. J. The PAI-1/vitronectin interaction: two cats in a bag? Thrombosis and Haemostasis  1995 74:66-70  PMID:8578527
  • Deng, H. X., Hentati, A., Tainer, J. A., Iqbal, Z., Cayabyab, A., Hung, W. Y., Getzoff, E. D., Hu, P., Herzfeldt, B., Roos, R. P., Warner, C., Deng, G., et al. Amyotrophic-lateral-sclerosis and structural defects in Cu,Zn superoxide-dismutase Science  1993 261:1047-1051  DOI:10.1126/science.8351519  PMID:8351519