recent publications

• academic article

  • Sehrawat, S., Koenig, P. A., Kirak, O., Schlieker, C., Fankhauser, M., Ploegh, H. L. A catalytically inactive mutant of the deubiquitylase YOD-1 enhances antigen cross-presentation Blood  2013 121:1145-1156  DOI:10.1182/blood-2012-08-447409  PMID:23243279  PMCID:PMC3575758
  • Avalos, A. M., Kirak, O., Oelkers, J. M., Pils, M. C., Kim, Y. M., Ottinger, M., Jaenisch, R., Ploegh, H. L., Brinkmann, M. M. Cell-specific TLR9 trafficking in primary APCs of transgenic TLR9-GFP mice Journal of Immunology  2013 190:695-702  DOI:10.4049/jimmunol.1202342  PMID:23241879  PMCID:PMC3539690
  • Sehrawat, S., Kirak, O., Koenig, P. A., Isaacson, M. K., Marques, S., Bozkurt, G., Simas, J. P., Jaenisch, R., Ploegh, H. L. CD8(+) T cells from mice transnuclear for a TCR that recognizes a single H-2K(b)-restricted MHV68 epitope derived from gB-ORF8 help control infection Cell Reports  2012 1:461-471  DOI:10.1016/j.celrep.2012.03.009  PMID:22832272  PMCID:PMC3406328
  • Ernst, R., Claessen, J. H. L., Mueller, B., Sanyal, S., Spooner, E., van der Veen, A. G., Kirak, O., Schlieker, C. D., Weihofen, W. A., Ploegh, H. L. Enzymatic blockade of the ubiquitin-proteasome pathway PLoS Biology  2011 9:e1000605  DOI:10.1371/journal.pbio.1000605  PMID:21468303  PMCID:PMC3066133
  • McGehee, A. M., Strijbis, K., Guillen, E., Eng, T., Kirak, O., Ploegh, H. L. Ubiquitin-dependent control of class II MHC localization is dispensable for antigen presentation and antibody production PLoS One  2011 6:e18817  DOI:10.1371/journal.pone.0018817  PMID:21533087  PMCID:PMC3080378
  • Kirak, O., Frickel, E. M., Grotenbreg, G. M., Suh, H., Jaenisch, R., Ploegh, H. L. Transnuclear mice with pre-defined T cell receptor specificities against Toxoplasma gondii obtained via SCNT Journal of Visualized Experiments : JoVE  2010  DOI:10.3791/2168  PMID:20972401  PMCID:PMC3157875
  • Kirak, O., Frickel, E. M., Grotenbreg, G. M., Suh, H., Jaenisch, R., Ploegh, H. L. Transnuclear mice with predefined T cell receptor specificities against Toxoplasma gondii obtained via SCNT Science  2010 328:243-248  DOI:10.1126/science.1178590  PMID:20378817  PMCID:PMC2940321
  • Brinkmann, M. M., Spooner, E., Hoebe, K., Beutler, B., Ploegh, H. L., Kim, Y. M. The interaction between the er membrane protein unc93b and tlr3, 7, and 9 is crucial for tlr signaling Journal of Cell Biology  2007 177:265-275  DOI:10.1083/jcb.200612056  PMID:17452530  PMCID:PMC2064135
  • Wang, E. W., Kessler, B. M., Borodovsky, A., Cravatt, B. F., Bogyo, M., Ploegh, H. L., Glas, R. Integration of the ubiquitin-proteasome pathway with a cytosolic oligopeptidase activity Proceedings of the National Academy of Sciences of the United States of America  2000 97:9990-9995  DOI:10.1073/pnas.180328897  PMID:10954757  PMCID:PMC27648