recent publications
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academic article
- Sehrawat, S., Koenig, P. A., Kirak, O., Schlieker, C., Fankhauser, M., Ploegh, H. L. A catalytically inactive mutant of the deubiquitylase YOD-1 enhances antigen cross-presentation Blood 2013 121:1145-1156 DOI:10.1182/blood-2012-08-447409 PMID:23243279 PMCID:PMC3575758
- Avalos, A. M., Kirak, O., Oelkers, J. M., Pils, M. C., Kim, Y. M., Ottinger, M., Jaenisch, R., Ploegh, H. L., Brinkmann, M. M. Cell-specific TLR9 trafficking in primary APCs of transgenic TLR9-GFP mice Journal of Immunology 2013 190:695-702 DOI:10.4049/jimmunol.1202342 PMID:23241879 PMCID:PMC3539690
- Sehrawat, S., Kirak, O., Koenig, P. A., Isaacson, M. K., Marques, S., Bozkurt, G., Simas, J. P., Jaenisch, R., Ploegh, H. L. CD8(+) T cells from mice transnuclear for a TCR that recognizes a single H-2K(b)-restricted MHV68 epitope derived from gB-ORF8 help control infection Cell Reports 2012 1:461-471 DOI:10.1016/j.celrep.2012.03.009 PMID:22832272 PMCID:PMC3406328
- McGehee, A. M., Strijbis, K., Guillen, E., Eng, T., Kirak, O., Ploegh, H. L. Ubiquitin-dependent control of class II MHC localization is dispensable for antigen presentation and antibody production PLoS One 2011 6:e18817 DOI:10.1371/journal.pone.0018817 PMID:21533087 PMCID:PMC3080378
- Ernst, R., Claessen, J. H. L., Mueller, B., Sanyal, S., Spooner, E., van der Veen, A. G., Kirak, O., Schlieker, C. D., Weihofen, W. A., Ploegh, H. L. Enzymatic blockade of the ubiquitin-proteasome pathway PLoS Biology 2011 9:e1000605 DOI:10.1371/journal.pbio.1000605 PMID:21468303 PMCID:PMC3066133
- Kirak, O., Frickel, E. M., Grotenbreg, G. M., Suh, H., Jaenisch, R., Ploegh, H. L. Transnuclear mice with pre-defined T cell receptor specificities against Toxoplasma gondii obtained via SCNT Journal of Visualized Experiments : JoVE 2010 DOI:10.3791/2168 PMID:20972401 PMCID:PMC3157875
- Kirak, O., Frickel, E. M., Grotenbreg, G. M., Suh, H., Jaenisch, R., Ploegh, H. L. Transnuclear mice with predefined T cell receptor specificities against Toxoplasma gondii obtained via SCNT Science 2010 328:243-248 DOI:10.1126/science.1178590 PMID:20378817 PMCID:PMC2940321
- Brinkmann, M. M., Spooner, E., Hoebe, K., Beutler, B., Ploegh, H. L., Kim, Y. M. The interaction between the er membrane protein unc93b and tlr3, 7, and 9 is crucial for tlr signaling Journal of Cell Biology 2007 177:265-275 DOI:10.1083/jcb.200612056 PMID:17452530 PMCID:PMC2064135
- Wang, E. W., Kessler, B. M., Borodovsky, A., Cravatt, B. F., Bogyo, M., Ploegh, H. L., Glas, R. Integration of the ubiquitin-proteasome pathway with a cytosolic oligopeptidase activity Proceedings of the National Academy of Sciences of the United States of America 2000 97:9990-9995 DOI:10.1073/pnas.180328897 PMID:10954757 PMCID:PMC27648