related to degree

• Halvorsen, Geoff, Ph.D. in Chemistry, Scripps Research , Transferred from University of Michigan 2005 - 2012

authors

• Halvorsen, Geoff
• Roush, William

publication date

• May 2007

journal

• Organic Letters  Journal

abstract

• The synthesis of siloxacyclopentene-constrained trienes 7 and 10 and studies of their IMDA cycloadditions are described. The use of appropriately chosen thermal or Lewis acid conditions allows for cycloadducts 3-6 to be obtained with high levels of diastereoselectivity. These adducts possess trans-relationships between the hydroxyl group and the adjacent ring fusion proton, a stereochemical relationship not previously attainable in IMDA reactions.

subject areas

• Cyclopentanes
• Molecular Structure
• Siloxanes

PubMed Central ID

• PMC2504012

International Standard Serial Number (ISSN)

• 1523-7060

Digital Object Identifier (DOI)

• 10.1021/ol070858u

PubMed ID

• 17480094

start page

• 2243

end page

• 2246

volume

• 9

issue

• 11