Triazolyl tryptoline derivatives as beta-secretase inhibitors

Academic Article

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• Research
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Overview

authors

• Jiaranaikulwanitch, J.
• Boonyarat, C.
• Fokin, Valery
• Vajragupta, O.

publication date

• 2010

journal

• Bioorganic & Medicinal Chemistry Letters  Journal

subject areas

• Amyloid Precursor Protein Secretases
• Carbolines
• Enzyme Inhibitors
• Triazoles

Research

keywords

• BACE1
• BACE1 inhibitor
• Binding mode
• Cathepsin-D
• Docking
• Enzyme assay
• JJCA-140
• Tryptoline

Identity

PubMed Central ID

• PMC3055559

International Standard Serial Number (ISSN)

• 0960-894X

Digital Object Identifier (DOI)

• 10.1016/j.bmcl.2010.09.043

PubMed ID

• 20943389

Additional Document Info

start page

• 6572

end page

• 6576

volume

• 20

issue

• 22