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Structural basis for drug and substrate specificity exhibited by FIV encoding a chimeric FIV/HIV protease

Academic Article
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Overview

authors

  • Lin, Y. C.
  • Perryman, A. L.
  • Olson, Arthur
  • Torbett, Bruce
  • Elder, John
  • Stout, C. David

publication date

  • June 2011

journal

  • Acta Crystallographica Section D-Biological Crystallography  Journal

subject areas

  • Aspartic Acid Endopeptidases
  • Crystallography, X-Ray
  • HIV
  • HIV Protease
  • Immunodeficiency Virus, Feline
  • Models, Molecular
  • Protein Structure, Quaternary
  • Protein Structure, Tertiary
  • Recombinant Proteins
  • Substrate Specificity
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Research

keywords

  • HIV protease
  • chimeric FIV
  • darunavir
  • feline immunodeficiency virus
  • lopinavir
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Identity

PubMed Central ID

  • PMC3107052

International Standard Serial Number (ISSN)

  • 0907-4449

Digital Object Identifier (DOI)

  • 10.1107/s0907444911011681

PubMed ID

  • 21636894
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Additional Document Info

start page

  • 540

end page

  • 548

volume

  • 67

issue

  • Pt 6

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