recent publications
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academic article
- Berk, J. L., Suhr, O. B., Obici, L., Sekijima, Y., Zeldenrust, S. R., Yamashita, T., Heneghan, M. A., Gorevic, P. D., Litchy, W. J., Wiesman, J. F., Nordh, E., Corato, M., et al. Repurposing diflunisal for familial amyloid polyneuropathy: a randomized clinical trial JAMA-Journal of the American Medical Association 2013 310:2658-2667 DOI:10.1001/jama.2013.283815 PMID:24368466 PMCID:PMC4139164
- Iwata, M., Lee, Y., Yamashita, T., Yagi, T., Iwata, S., Cameron, A. D., Maher, M. J. The structure of the yeast nadh dehydrogenase (ndi1) reveals overlapping binding sites for water- and lipid-soluble substrates Proceedings of the National Academy of Sciences of the United States of America 2012 109:15247-15252 DOI:10.1073/pnas.1210059109 PMID:22949654 PMCID:PMC3458368
- Berk, J. L., Suhr, O. B., Sekijima, Y., Yamashita, T., Heneghan, M., Zeldenrust, S. R., Ando, Y., Ikeda, S., Gorevic, P., Merlini, G., Kelly, J. W., Skinner, M., et al. The Diflunisal Trial: Study accrual and drug tolerance Amyloid-Journal of Protein Folding Disorders 2012 19:37-38 DOI:10.3109/13506129.2012.678509 PMID:22551208
- Yang, Y., Yamashita, T., Nakamaru-Ogiso, E., Hashimoto, T., Murai, M., Igarashi, J., Miyoshi, H., Mori, N., Matsuno-Yagi, A., Yagi, T., Kosaka, H. Reaction mechanism of single subunit nadh-ubiquinone oxidoreductase (ndi1) from saccharomyces cerevisiae evidence for a ternary complex mechanism Journal of Biological Chemistry 2011 286:9287-9297 DOI:10.1074/jbc.M110.175547 PMID:21220430 PMCID:PMC3059053
- Murai, M., Yamashita, T., Senoh, M., Mashimo, Y., Kataoka, M., Kosaka, H., Matsuno-Yagi, A., Yagi, T., Miyoshi, H. Characterization of the ubiquinone binding site in the alternative nadh-quinone oxidoreductase of saccharomyces cerevisiae by photoaffinity labeling Biochemistry 2010 49:2973-2980 DOI:10.1021/bi100005j PMID:20192260 PMCID:PMC2847623
- Yamashita, T., Nakamaru-Ogiso, E., Miyoshi, H., Matsuno-Yagi, A., Yagi, T. Roles of bound quinone in the single subunit nadh-quinone oxidoreductase (ndi1) from saccharomyces cerevisiae Journal of Biological Chemistry 2007 282:6012-6020 DOI:10.1074/jbc.M610646200 PMID:17200125
- Yagi, T., Seo, B. B., Nakamaru-Ogiso, E., Marella, M., Barber-Singh, J., Yamashita, T., Matsuno-Yagi, A. Possibility of transkingdom gene therapy for complex i diseases Biochimica et Biophysica Acta-Bioenergetics 2006 1757:708-714 DOI:10.1016/j.bbabio.2006.01.011
- Yagi, T., Seo, B. B., Nakamaru-Ogiso, E., Marella, M., Barber-Singh, J., Yamashita, T., Kao, M. C., Matsuno-Yagi, A. Can a single subunit yeast nadh dehydrogenase (ndi1) remedy diseases caused by respiratory complex i defects? Rejuvenation Research 2006 9:191-197 DOI:10.1089/rej.2006.9.191 PMID:16706641
- Zhou, D. P., Mattner, J., Cantu, C., Schrantz, N., Yin, N., Gao, Y., Sagiv, Y., Hudspeth, K., Wu, Y. P., Yamashita, T., Teneberg, S., Wang, D. C., et al. Lysosomal glycosphingolipid recognition by NKT cells Science 2004 306:1786-1789 DOI:10.1126/science/1103440 PMID:15539565