recent publications

• academic article

  • Berk, J. L., Suhr, O. B., Obici, L., Sekijima, Y., Zeldenrust, S. R., Yamashita, T., Heneghan, M. A., Gorevic, P. D., Litchy, W. J., Wiesman, J. F., Nordh, E., Corato, M., et al. Repurposing diflunisal for familial amyloid polyneuropathy: a randomized clinical trial JAMA-Journal of the American Medical Association  2013 310:2658-2667  DOI:10.1001/jama.2013.283815  PMID:24368466  PMCID:PMC4139164
  • Iwata, M., Lee, Y., Yamashita, T., Yagi, T., Iwata, S., Cameron, A. D., Maher, M. J. The structure of the yeast nadh dehydrogenase (ndi1) reveals overlapping binding sites for water- and lipid-soluble substrates Proceedings of the National Academy of Sciences of the United States of America  2012 109:15247-15252  DOI:10.1073/pnas.1210059109  PMID:22949654  PMCID:PMC3458368
  • Berk, J. L., Suhr, O. B., Sekijima, Y., Yamashita, T., Heneghan, M., Zeldenrust, S. R., Ando, Y., Ikeda, S., Gorevic, P., Merlini, G., Kelly, J. W., Skinner, M., et al. The Diflunisal Trial: Study accrual and drug tolerance Amyloid-Journal of Protein Folding Disorders  2012 19:37-38  DOI:10.3109/13506129.2012.678509  PMID:22551208
  • Yang, Y., Yamashita, T., Nakamaru-Ogiso, E., Hashimoto, T., Murai, M., Igarashi, J., Miyoshi, H., Mori, N., Matsuno-Yagi, A., Yagi, T., Kosaka, H. Reaction mechanism of single subunit nadh-ubiquinone oxidoreductase (ndi1) from saccharomyces cerevisiae evidence for a ternary complex mechanism Journal of Biological Chemistry  2011 286:9287-9297  DOI:10.1074/jbc.M110.175547  PMID:21220430  PMCID:PMC3059053
  • Murai, M., Yamashita, T., Senoh, M., Mashimo, Y., Kataoka, M., Kosaka, H., Matsuno-Yagi, A., Yagi, T., Miyoshi, H. Characterization of the ubiquinone binding site in the alternative nadh-quinone oxidoreductase of saccharomyces cerevisiae by photoaffinity labeling Biochemistry  2010 49:2973-2980  DOI:10.1021/bi100005j  PMID:20192260  PMCID:PMC2847623
  • Yamashita, T., Nakamaru-Ogiso, E., Miyoshi, H., Matsuno-Yagi, A., Yagi, T. Roles of bound quinone in the single subunit nadh-quinone oxidoreductase (ndi1) from saccharomyces cerevisiae Journal of Biological Chemistry  2007 282:6012-6020  DOI:10.1074/jbc.M610646200  PMID:17200125
  • Yagi, T., Seo, B. B., Nakamaru-Ogiso, E., Marella, M., Barber-Singh, J., Yamashita, T., Matsuno-Yagi, A. Possibility of transkingdom gene therapy for complex i diseases Biochimica et Biophysica Acta-Bioenergetics  2006 1757:708-714  DOI:10.1016/j.bbabio.2006.01.011
  • Yagi, T., Seo, B. B., Nakamaru-Ogiso, E., Marella, M., Barber-Singh, J., Yamashita, T., Kao, M. C., Matsuno-Yagi, A. Can a single subunit yeast nadh dehydrogenase (ndi1) remedy diseases caused by respiratory complex i defects? Rejuvenation Research  2006 9:191-197  DOI:10.1089/rej.2006.9.191  PMID:16706641
  • Zhou, D. P., Mattner, J., Cantu, C., Schrantz, N., Yin, N., Gao, Y., Sagiv, Y., Hudspeth, K., Wu, Y. P., Yamashita, T., Teneberg, S., Wang, D. C., et al. Lysosomal glycosphingolipid recognition by NKT cells Science  2004 306:1786-1789  DOI:10.1126/science/1103440  PMID:15539565