Scripps VIVO scripps research logo

  • Index
  • Log in
  • Home
  • People
  • Organizations
  • Research
  • Events
Search form
As of April 1st VIVO Scientific Profiles will no longer updated for faculty, and the link to VIVO will be removed from the library website. Faculty profile pages will continue to be updated via Interfolio. VIVO will continue being used behind the scenes to update graduate student profiles. Please contact helplib@scripps.edu if you have questions.
How to download citations from VIVO | Alternative profile options

The role of Drosophila mushroom body signaling in olfactory memory

Academic Article
uri icon
  • Overview
  • Identity
  • Additional Document Info
  • View All
scroll to property group menus

Overview

authors

  • McGuire, S. E.
  • Le, P. T.
  • Davis, Ronald

publication date

  • August 2001

journal

  • Science  Journal

abstract

  • The mushroom bodies of the Drosophila brain are important for olfactory learning and memory. To investigate the requirement for mushroom body signaling during the different phases of memory processing, we transiently inactivated neurotransmission through this region of the brain by expressing a temperature-sensitive allele of the shibire dynamin guanosine triphosphatase, which is required for synaptic transmission. Inactivation of mushroom body signaling through alpha/beta neurons during different phases of memory processing revealed a requirement for mushroom body signaling during memory retrieval, but not during acquisition or consolidation.

subject areas

  • Afferent Pathways
  • Animals
  • Brain
  • Conditioning, Classical
  • Drosophila
  • Drosophila Proteins
  • Dynamins
  • Electroshock
  • GTP Phosphohydrolases
  • Gene Targeting
  • Genes, Insect
  • Memory
  • Mental Recall
  • Mutation
  • Neurons
  • Odorants
  • Signal Transduction
  • Synaptic Transmission
  • Temperature
  • Transgenes
scroll to property group menus

Identity

International Standard Serial Number (ISSN)

  • 0036-8075

Digital Object Identifier (DOI)

  • 10.1126/science.1062622

PubMed ID

  • 11397912
scroll to property group menus

Additional Document Info

start page

  • 1330

end page

  • 1333

volume

  • 293

issue

  • 5533

©2022 The Scripps Research Institute | Terms of Use | Powered by VIVO

  • About
  • Contact Us
  • Support