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Leptin enhances the potency of circulating angiogenic cells via src kinase and integrin alpha v beta 5: implications for angiogenesis in human obesity

Academic Article
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Overview

authors

  • Heida, N. M.
  • Leifheit-Nestler, M.
  • Schroeter, M. R.
  • Muller, J. P.
  • Cheng, I. F.
  • Henkel, S.
  • Limbourg, A.
  • Limbourg, F. P.
  • Alves, F.
  • Quigley, James
  • Ruggeri, Zaverio
  • Hasenfuss, G.
  • Konstantinides, S.
  • Schafer, K.

publication date

  • 2010

journal

  • Arteriosclerosis, Thrombosis, and Vascular Biology  Journal

subject areas

  • Animals
  • Antigens, CD31
  • Antigens, CD34
  • Antigens, CD45
  • Case-Control Studies
  • Cell Adhesion
  • Cell Movement
  • Chick Embryo
  • Chorioallantoic Membrane
  • Disease Models, Animal
  • Endothelial Cells
  • Enzyme Activation
  • Hindlimb
  • Humans
  • Ischemia
  • Janus Kinase 2
  • Leptin
  • Leukocytes, Mononuclear
  • Male
  • Mice
  • Mice, Nude
  • Muscle, Skeletal
  • Neovascularization, Physiologic
  • Obesity
  • Phospholipase C gamma
  • Phosphorylation
  • Protein Tyrosine Phosphatase, Non-Receptor Type 1
  • Receptors, Leptin
  • Receptors, Vitronectin
  • Recombinant Proteins
  • Signal Transduction
  • Spheroids, Cellular
  • Transfection
  • Up-Regulation
  • Weight Loss
  • src-Family Kinases
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Research

keywords

  • PTP1B
  • Src kinase
  • angiogenesis
  • circulating angiogenic cells
  • leptin
  • obesity
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Identity

PubMed Central ID

  • PMC2824857

International Standard Serial Number (ISSN)

  • 1079-5642

Digital Object Identifier (DOI)

  • 10.1161/atvbaha.109.192807

PubMed ID

  • 19910644
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Additional Document Info

start page

  • 200

end page

  • 206

volume

  • 30

issue

  • 2

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