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Encoded reaction cassette for the highly sensitive detection of the making and breaking of chemical-bonds

Academic Article
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Overview

authors

  • Fenniri, H.
  • Janda, Kim
  • Lerner, Richard

publication date

  • March 1995

journal

  • Proceedings of the National Academy of Sciences of the United States of America  Journal

abstract

  • A reaction cassette has been designed for the highly sensitive detection of the making and breaking of chemical bonds. The system is envisioned as a companion device to be used in the search for antibody and other novel catalysts. The cassette also may have important clinical applications in the design of diagnostic reagents. In its fully encoded format, this methodology is capable of both detecting and decoding chemical events.

subject areas

  • Antibodies
  • Base Sequence
  • Catalysis
  • Chemistry
  • DNA
  • DNA Primers
  • Endopeptidases
  • Enzyme-Linked Immunosorbent Assay
  • Molecular Sequence Data
  • Mutagenesis, Insertional
  • Oligodeoxyribonucleotides
  • Peptides
  • Polymerase Chain Reaction
  • Sensitivity and Specificity
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Identity

International Standard Serial Number (ISSN)

  • 0027-8424

Digital Object Identifier (DOI)

  • 10.1073/pnas.92.6.2278

PubMed ID

  • 7892261
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Additional Document Info

start page

  • 2278

end page

  • 2282

volume

  • 92

issue

  • 6

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